2FAM
 
 | X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES | Descriptor: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION | Authors: | Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M. | Deposit date: | 1993-07-20 | Release date: | 1993-10-31 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states. J.Mol.Biol., 233, 1993
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2FAL
 
 | X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES | Descriptor: | CYANIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M. | Deposit date: | 1993-06-14 | Release date: | 1993-10-31 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states. J.Mol.Biol., 233, 1993
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1BCU
 
 | ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN | Descriptor: | ALPHA-THROMBIN, HIRUGEN, PROFLAVIN | Authors: | Conti, E, Rivetti, C, Wonacott, A, Brick, P. | Deposit date: | 1998-05-02 | Release date: | 1998-10-14 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin. FEBS Lett., 425, 1998
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1AMU
 
 | PHENYLALANINE ACTIVATING DOMAIN OF GRAMICIDIN SYNTHETASE 1 IN A COMPLEX WITH AMP AND PHENYLALANINE | Descriptor: | ADENOSINE MONOPHOSPHATE, GRAMICIDIN SYNTHETASE 1, MAGNESIUM ION, ... | Authors: | Conti, E, Stachelhaus, T, Marahiel, M.A, Brick, P. | Deposit date: | 1997-06-18 | Release date: | 1998-07-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S. EMBO J., 16, 1997
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1EE5
 
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1EE4
 
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1BK6
 
 | KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS | Descriptor: | KARYOPHERIN ALPHA, LARGE T ANTIGEN | Authors: | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | Deposit date: | 1998-07-14 | Release date: | 1999-01-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell(Cambridge,Mass.), 94, 1998
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1BK5
 
 | KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE | Descriptor: | COBALT (II) ION, KARYOPHERIN ALPHA | Authors: | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | Deposit date: | 1998-07-14 | Release date: | 1999-01-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell(Cambridge,Mass.), 94, 1998
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1LCI
 
 | FIREFLY LUCIFERASE | Descriptor: | LUCIFERASE | Authors: | Conti, E, Franks, N.P, Brick, P. | Deposit date: | 1996-06-01 | Release date: | 1997-03-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes. Structure, 4, 1996
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4W8Z
 
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4U4C
 
 | The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities | Descriptor: | 1,2-ETHANEDIOL, ATP-dependent RNA helicase DOB1, CHLORIDE ION, ... | Authors: | Falk, S, Weir, J.R, Hentschel, J, Reichelt, P, Bonneau, F, Conti, E. | Deposit date: | 2014-07-23 | Release date: | 2014-09-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities. Mol.Cell, 55, 2014
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1BA3
 
 | FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM | Descriptor: | LUCIFERASE, TRIBROMOMETHANE | Authors: | Franks, N.P, Jenkins, A, Conti, E, Lieb, W.R, Brick, P. | Deposit date: | 1998-04-21 | Release date: | 1998-11-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the inhibition of firefly luciferase by a general anesthetic. Biophys.J., 75, 1998
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8RXB
 
 | Human UPF1 CH domain in complex with SMG6 peptide | Descriptor: | Regulator of nonsense transcripts 1, Telomerase-binding protein EST1A, ZINC ION | Authors: | Langer, L, Basquin, J, Conti, E. | Deposit date: | 2024-02-06 | Release date: | 2024-05-15 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2. Nucleic Acids Res., 52, 2024
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5AJD
 
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6YVH
 
 | CWC22-CWC27-EIF4A3 Complex | Descriptor: | Eukaryotic initiation factor 4A-III, Pre-mRNA-splicing factor CWC22 homolog, Spliceosome-associated protein CWC27 homolog | Authors: | Basquin, J, Busetto, V, LeHir, H, Conti, E. | Deposit date: | 2020-04-28 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes. Nucleic Acids Res., 48, 2020
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2BR2
 
 | RNase PH core of the archaeal exosome | Descriptor: | CHLORIDE ION, EXOSOME COMPLEX EXONUCLEASE 1, EXOSOME COMPLEX EXONUCLEASE 2 | Authors: | lorentzen, E, Fribourg, S, Conti, E. | Deposit date: | 2005-04-30 | Release date: | 2005-06-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Archaeal Exosome Core is a Hexameric Ring Structure with Three Catalytic Subunits. Nat.Struct.Mol.Biol., 12, 2005
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4UM2
 
 | Crystal structure of the TPR domain of SMG6 | Descriptor: | GLYCEROL, TELOMERASE-BINDING PROTEIN EST1A | Authors: | Chakrabarti, S, Bonneau, F, Schuessler, S, Eppinger, E, Conti, E. | Deposit date: | 2014-05-14 | Release date: | 2014-07-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Phospho-Dependent and Phospho-Independent Interactions of the Helicase Upf1 with the Nmd Factors Smg5-Smg7 and Smg6. Nucleic Acids Res., 42, 2014
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1W3B
 
 | The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. | Descriptor: | CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 | Authors: | Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E. | Deposit date: | 2004-07-14 | Release date: | 2004-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha Nat.Struct.Mol.Biol., 11, 2004
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2C37
 
 | RNASE PH CORE OF THE ARCHAEAL EXOSOME IN COMPLEX WITH U8 RNA | Descriptor: | 5-O-phosphono-beta-D-ribofuranose, CHLORIDE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ... | Authors: | Lorentzen, E, Conti, E. | Deposit date: | 2005-10-04 | Release date: | 2005-11-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core. Mol.Cell, 20, 2005
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2C38
 
 | RNase PH core of the archaeal exosome in complex with A5 RNA | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ... | Authors: | Lorentzen, E, Conti, E. | Deposit date: | 2005-10-04 | Release date: | 2005-11-23 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core. Mol.Cell, 20, 2005
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6R5K
 
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4W8W
 
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3N89
 
 | KH domains | Descriptor: | Defective in germ line development protein 3, isoform a | Authors: | Nakel, K, Hartung, S.A, Bonneau, F, Eckmann, C.R, Conti, E. | Deposit date: | 2010-05-28 | Release date: | 2010-09-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.789 Å) | Cite: | Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform. Rna, 16, 2010
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5JEA
 
 | Structure of a cytoplasmic 11-subunit RNA exosome complex including Ski7, bound to RNA | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Exosome complex component CSL4, Exosome complex component MTR3, ... | Authors: | Kowalinski, E, Ebert, J, Stegmann, E, Conti, E. | Deposit date: | 2016-04-18 | Release date: | 2016-07-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex. Mol.Cell, 63, 2016
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4N0L
 
 | Methanopyrus kandleri Csm3 crystal structure | Descriptor: | Predicted component of a thermophile-specific DNA repair system, contains a RAMP domain, ZINC ION | Authors: | Hrle, A, Su, A.A, Ebert, J, Benda, C, Conti, E, Randau, L. | Deposit date: | 2013-10-02 | Release date: | 2013-11-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structure and RNA-binding properties of the Type III-A CRISPR-associated protein Csm3. Rna Biol., 10, 2013
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