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2FAM
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BU of 2fam by Molmil
X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, THIOCYANATE ION
Authors:Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M.
Deposit date:1993-07-20
Release date:1993-10-31
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
J.Mol.Biol., 233, 1993
2FAL
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BU of 2fal by Molmil
X-RAY CRYSTAL STRUCTURE OF FERRIC APLYSIA LIMACINA MYOGLOBIN IN DIFFERENT LIGANDED STATES
Descriptor: CYANIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Conti, E, Moser, C, Rizzi, M, Mattevi, A, Lionetti, C, Coda, A, Ascenzi, P, Brunori, M, Bolognesi, M.
Deposit date:1993-06-14
Release date:1993-10-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
J.Mol.Biol., 233, 1993
1BCU
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BU of 1bcu by Molmil
ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN
Descriptor: ALPHA-THROMBIN, HIRUGEN, PROFLAVIN
Authors:Conti, E, Rivetti, C, Wonacott, A, Brick, P.
Deposit date:1998-05-02
Release date:1998-10-14
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.
FEBS Lett., 425, 1998
1AMU
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BU of 1amu by Molmil
PHENYLALANINE ACTIVATING DOMAIN OF GRAMICIDIN SYNTHETASE 1 IN A COMPLEX WITH AMP AND PHENYLALANINE
Descriptor: ADENOSINE MONOPHOSPHATE, GRAMICIDIN SYNTHETASE 1, MAGNESIUM ION, ...
Authors:Conti, E, Stachelhaus, T, Marahiel, M.A, Brick, P.
Deposit date:1997-06-18
Release date:1998-07-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S.
EMBO J., 16, 1997
1EE5
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BU of 1ee5 by Molmil
YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A NUCLEOPLASMIN NLS PEPTIDE
Descriptor: KARYOPHERIN ALPHA, NUCLEOPLASMIN
Authors:Conti, E.
Deposit date:2000-01-30
Release date:2000-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure Fold.Des., 8, 2000
1EE4
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BU of 1ee4 by Molmil
CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE
Descriptor: KARYOPHERIN ALPHA, MYC PROTO-ONCOGENE PROTEIN
Authors:Conti, E.
Deposit date:2000-01-30
Release date:2000-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure Fold.Des., 8, 2000
1BK6
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BU of 1bk6 by Molmil
KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS
Descriptor: KARYOPHERIN ALPHA, LARGE T ANTIGEN
Authors:Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
Deposit date:1998-07-14
Release date:1999-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1BK5
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BU of 1bk5 by Molmil
KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE
Descriptor: COBALT (II) ION, KARYOPHERIN ALPHA
Authors:Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
Deposit date:1998-07-14
Release date:1999-01-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1LCI
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BU of 1lci by Molmil
FIREFLY LUCIFERASE
Descriptor: LUCIFERASE
Authors:Conti, E, Franks, N.P, Brick, P.
Deposit date:1996-06-01
Release date:1997-03-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes.
Structure, 4, 1996
4W8Z
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BU of 4w8z by Molmil
Crystal structure of Cmr1 from Pyrococcus furiosus (apo form)
Descriptor: CRISPR system Cmr subunit Cmr1-1
Authors:Benda, C, Ebert, J, Baumgaertner, M, Conti, E.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4.
Mol.Cell, 56, 2014
4U4C
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BU of 4u4c by Molmil
The molecular architecture of the TRAMP complex reveals the organization and interplay of its two catalytic activities
Descriptor: 1,2-ETHANEDIOL, ATP-dependent RNA helicase DOB1, CHLORIDE ION, ...
Authors:Falk, S, Weir, J.R, Hentschel, J, Reichelt, P, Bonneau, F, Conti, E.
Deposit date:2014-07-23
Release date:2014-09-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Molecular Architecture of the TRAMP Complex Reveals the Organization and Interplay of Its Two Catalytic Activities.
Mol.Cell, 55, 2014
1BA3
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BU of 1ba3 by Molmil
FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Descriptor: LUCIFERASE, TRIBROMOMETHANE
Authors:Franks, N.P, Jenkins, A, Conti, E, Lieb, W.R, Brick, P.
Deposit date:1998-04-21
Release date:1998-11-11
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the inhibition of firefly luciferase by a general anesthetic.
Biophys.J., 75, 1998
8RXB
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BU of 8rxb by Molmil
Human UPF1 CH domain in complex with SMG6 peptide
Descriptor: Regulator of nonsense transcripts 1, Telomerase-binding protein EST1A, ZINC ION
Authors:Langer, L, Basquin, J, Conti, E.
Deposit date:2024-02-06
Release date:2024-05-15
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:UPF1 helicase orchestrates mutually exclusive interactions with the SMG6 endonuclease and UPF2.
Nucleic Acids Res., 52, 2024
5AJD
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BU of 5ajd by Molmil
Not1 C-terminal domain in complex with Not4
Descriptor: CDC39P, GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 4
Authors:Bhaskar, V, Basquin, J, Conti, E.
Deposit date:2015-02-23
Release date:2015-04-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.62 Å)
Cite:Architecture of the Ubiquitylation Module of the Yeast Ccr4-not Complex.
Structure, 23, 2015
6YVH
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BU of 6yvh by Molmil
CWC22-CWC27-EIF4A3 Complex
Descriptor: Eukaryotic initiation factor 4A-III, Pre-mRNA-splicing factor CWC22 homolog, Spliceosome-associated protein CWC27 homolog
Authors:Basquin, J, Busetto, V, LeHir, H, Conti, E.
Deposit date:2020-04-28
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.
Nucleic Acids Res., 48, 2020
2BR2
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BU of 2br2 by Molmil
RNase PH core of the archaeal exosome
Descriptor: CHLORIDE ION, EXOSOME COMPLEX EXONUCLEASE 1, EXOSOME COMPLEX EXONUCLEASE 2
Authors:lorentzen, E, Fribourg, S, Conti, E.
Deposit date:2005-04-30
Release date:2005-06-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Archaeal Exosome Core is a Hexameric Ring Structure with Three Catalytic Subunits.
Nat.Struct.Mol.Biol., 12, 2005
4UM2
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BU of 4um2 by Molmil
Crystal structure of the TPR domain of SMG6
Descriptor: GLYCEROL, TELOMERASE-BINDING PROTEIN EST1A
Authors:Chakrabarti, S, Bonneau, F, Schuessler, S, Eppinger, E, Conti, E.
Deposit date:2014-05-14
Release date:2014-07-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Phospho-Dependent and Phospho-Independent Interactions of the Helicase Upf1 with the Nmd Factors Smg5-Smg7 and Smg6.
Nucleic Acids Res., 42, 2014
1W3B
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BU of 1w3b by Molmil
The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Descriptor: CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110
Authors:Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E.
Deposit date:2004-07-14
Release date:2004-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
2C37
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BU of 2c37 by Molmil
RNASE PH CORE OF THE ARCHAEAL EXOSOME IN COMPLEX WITH U8 RNA
Descriptor: 5-O-phosphono-beta-D-ribofuranose, CHLORIDE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ...
Authors:Lorentzen, E, Conti, E.
Deposit date:2005-10-04
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20, 2005
2C38
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BU of 2c38 by Molmil
RNase PH core of the archaeal exosome in complex with A5 RNA
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, PROBABLE EXOSOME COMPLEX EXONUCLEASE 1, ...
Authors:Lorentzen, E, Conti, E.
Deposit date:2005-10-04
Release date:2005-11-23
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of 3' End RNA Recognition and Exoribonucleolytic Cleavage by an Exosome Rnase Ph Core.
Mol.Cell, 20, 2005
6R5K
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BU of 6r5k by Molmil
Cryo-EM structure of a poly(A) RNP bound to the Pan2-Pan3 deadenylase
Descriptor: MAGNESIUM ION, PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAN2-PAN3 deadenylation complex subunit PAN3, ...
Authors:Schaefer, I.B, Conti, E.
Deposit date:2019-03-25
Release date:2019-05-29
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular Basis for poly(A) RNP Architecture and Recognition by the Pan2-Pan3 Deadenylase.
Cell, 177, 2019
4W8W
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BU of 4w8w by Molmil
Crystal structure of oligomeric Cmr4 from Pyrococcus furiosus
Descriptor: CRISPR system Cmr subunit Cmr4
Authors:Benda, C, Ebert, J, Baumgaertner, M, Conti, E.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4.
Mol.Cell, 56, 2014
3N89
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BU of 3n89 by Molmil
KH domains
Descriptor: Defective in germ line development protein 3, isoform a
Authors:Nakel, K, Hartung, S.A, Bonneau, F, Eckmann, C.R, Conti, E.
Deposit date:2010-05-28
Release date:2010-09-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Four KH domains of the C. elegans Bicaudal-C ortholog GLD-3 form a globular structural platform.
Rna, 16, 2010
5JEA
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BU of 5jea by Molmil
Structure of a cytoplasmic 11-subunit RNA exosome complex including Ski7, bound to RNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Exosome complex component CSL4, Exosome complex component MTR3, ...
Authors:Kowalinski, E, Ebert, J, Stegmann, E, Conti, E.
Deposit date:2016-04-18
Release date:2016-07-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex.
Mol.Cell, 63, 2016
4N0L
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BU of 4n0l by Molmil
Methanopyrus kandleri Csm3 crystal structure
Descriptor: Predicted component of a thermophile-specific DNA repair system, contains a RAMP domain, ZINC ION
Authors:Hrle, A, Su, A.A, Ebert, J, Benda, C, Conti, E, Randau, L.
Deposit date:2013-10-02
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure and RNA-binding properties of the Type III-A CRISPR-associated protein Csm3.
Rna Biol., 10, 2013

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