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1MQT
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BU of 1mqt by Molmil
Swine Vesicular Disease Virus coat protein
Descriptor: OCTANOIC ACID (2-HYDROXY-1-HYDROXYMETHYL-HEPTADEC-3-ENYL)-AMIDE, Polyprotein, Polyprotein Capsid Protein
Authors:Verdaguer, N, Jimenez-Clavero, M.A, Fita, I, Ley, V.
Deposit date:2002-09-17
Release date:2004-03-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:STRUCTURE OF SWINE VESICULAR DISEASE VIRUS: MAPPING OF CHANGES OCCURRING DURING ADAPTATION OF HUMAN COXSACKIE B5 VIRUS TO INFECT SWINE
J.Virol., 77, 2003
1DSY
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BU of 1dsy by Molmil
C2 DOMAIN FROM PROTEIN KINASE C (ALPHA) COMPLEXED WITH CA2+ AND PHOSPHATIDYLSERINE
Descriptor: 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, CALCIUM ION, PHOSPHATE ION, ...
Authors:Verdaguer, N, Corbalan-Garcia, S, Ochoa, W.F, Fita, I, Gomez-Fernandez, J.C.
Deposit date:2000-01-10
Release date:2000-01-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine.
EMBO J., 18, 1999
1V9U
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BU of 1v9u by Molmil
Human Rhinovirus 2 bound to a fragment of its cellular receptor protein
Descriptor: CALCIUM ION, Coat protein VP1, Coat protein VP2, ...
Authors:Verdaguer, N, Fita, I, Reithmayer, M, Moser, R, Blaas, D.
Deposit date:2004-02-03
Release date:2004-05-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:X-ray structure of a minor group human rhinovirus bound to a fragment of its cellular receptor protein
NAT.STRUCT.MOL.BIOL., 11, 2004
1FPN
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BU of 1fpn by Molmil
HUMAN RHINOVIRUS SEROTYPE 2 (HRV2)
Descriptor: COAT PROTEIN VP1, COAT PROTEIN VP2, COAT PROTEIN VP3, ...
Authors:Verdaguer, N, Blaas, D, Fita, I.
Deposit date:2000-08-31
Release date:2000-09-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human rhinovirus serotype 2 (HRV2).
J.Mol.Biol., 300, 2000
2D47
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BU of 2d47 by Molmil
MOLECULAR STRUCTURE OF A COMPLETE TURN OF A-DNA
Descriptor: DNA (5'-D(*CP*CP*CP*CP*CP*GP*CP*GP*GP*GP*GP*G)-3'), SPERMINE
Authors:Verdaguer, N, Aymami, J, Fernandez-Forner, D, Fita, I, Coll, M, Huynh-Dinh, T, Igolen, J, Subirana, J.A.
Deposit date:1991-10-02
Release date:1991-10-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular structure of a complete turn of A-DNA.
J.Mol.Biol., 221, 1991
5JXS
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BU of 5jxs by Molmil
Mutant GC216/7AA of 3D polymerase from Foot-and-Mouth Disease Virus
Descriptor: MAGNESIUM ION, RNA Primer, RNA Template, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2016-05-13
Release date:2016-06-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication.
J.Virol., 90, 2016
6GVY
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BU of 6gvy by Molmil
Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with an template -primer RNA
Descriptor: GLYCEROL, Genome polyprotein, RNA (5'-R(P*CP*CP*GP*GP*G)-3'), ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J. Virol., 92, 2018
6GVV
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BU of 6gvv by Molmil
Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus
Descriptor: GLYCEROL, RNA polymerase 3D
Authors:Verdaguer, N, Ferrer Orta, C.
Deposit date:2018-06-21
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.
J.Virol., 92, 2018
6S2L
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BU of 6s2l by Molmil
FMDV 3D polymerase crystallized in presence of (F)uridylylated VPg peptide
Descriptor: GLYCEROL, Genome polyprotein
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2019-06-21
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:(F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase.
Molecules, 24, 2019
4Y3C
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BU of 4y3c by Molmil
I304V 3D polymerase mutant of EMCV
Descriptor: 3D polymerase, CHLORIDE ION, GLYCEROL
Authors:Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L.
Deposit date:2015-02-10
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y2C
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BU of 4y2c by Molmil
M300V 3D polymerase mutant of EMCV
Descriptor: GLYCEROL, Genome polyprotein
Authors:Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L.
Deposit date:2015-02-09
Release date:2015-04-01
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4WZM
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BU of 4wzm by Molmil
Mutant K18E of RNA dependent RNA polymerase from Foot-and-Mouth Disease Virus complexed with RNA
Descriptor: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ...
Authors:Verdaguer, N, Ferrer-Orta, C, de la Higuera, N.
Deposit date:2014-11-20
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
5LOW
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BU of 5low by Molmil
Structure of the Ca2+-bound Rabphilin 3A C2B domain SNAP25 complex (P21 space group)
Descriptor: CALCIUM ION, GLYCEROL, Rabphilin-3A, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2016-08-10
Release date:2017-06-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural characterization of the Rabphilin-3A-SNAP25 interaction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4LT7
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BU of 4lt7 by Molmil
Crystal structure of the c2a domain of rabphilin-3a in complex with a calcium
Descriptor: CALCIUM ION, Rabphilin-3A
Authors:Verdaguer, N, Ferrer-Orta, C, Buxaderas, M, Corbalan-Garcia, S, Perez-Sanchez, D, Guerrero-Valero, M, Luengo, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Guillen, J.
Deposit date:2013-07-23
Release date:2013-12-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4WZQ
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BU of 4wzq by Molmil
Mutant K20E of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with RNA
Descriptor: MANGANESE (II) ION, RNA dependent-RNA polymerase 3D, RNA template, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2014-11-20
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
4X2B
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BU of 4x2b by Molmil
K20A RNA dependent RNA polymerase mutant from Foot-and-Mouth disease Virus complexed with an RNA
Descriptor: MAGNESIUM ION, RNA dependent RNA polymerase, RNA primer, ...
Authors:Verdaguer, N, Ferrer-Orta, C.
Deposit date:2014-11-26
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
1EJO
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BU of 1ejo by Molmil
FAB FRAGMENT OF NEUTRALISING MONOCLONAL ANTIBODY 4C4 COMPLEXED WITH G-H LOOP FROM FMDV.
Descriptor: FMDV PEPTIDE, IGG2A MONOCLONAL ANTIBODY (HEAVY CHAIN), IGG2A MONOCLONAL ANTIBODY (LIGHT CHAIN)
Authors:Ochoa, W.F, Kalko, S.G, Gomes, P, Fita, I, Verdaguer, N.
Deposit date:2000-03-03
Release date:2000-03-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A multiply substituted G-H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: a role for water molecules.
J.Gen.Virol., 81, 2000
6YDR
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BU of 6ydr by Molmil
Crystal structure of Mengla Virus VP30 C-terminal domain
Descriptor: GLYCEROL, Minor nucleoprotein VP30, SULFATE ION
Authors:Tomas Gilabert, O, Ferrero, D.S, Verdaguer, N.
Deposit date:2020-03-20
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Crystal structure of Mengla Virus VP30 C-terminal domain
To Be Published
4PDW
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BU of 4pdw by Molmil
A benzonitrile analogue inhibits rhinovirus replication
Descriptor: 4-[(4,5-dimethoxy-2-nitrophenyl)acetyl]benzonitrile, Capsid protein VP4/VP2, GLYCEROL, ...
Authors:Querol-Audi, J, Guerra, P, Lacroix, C, Roche, M, Franco, D, Froeyen, M, Terme, T, Vanelle, P, Neyts, J, Leyssen, P, Verdaguer, N.
Deposit date:2014-04-22
Release date:2014-07-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:A novel benzonitrile analogue inhibits rhinovirus replication.
J.Antimicrob.Chemother., 69, 2014
2E9R
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BU of 2e9r by Molmil
Foot-and-mouth disease virus RNA-dependent RNA polymerase in complex with a template-primer RNA and with ribavirin
Descriptor: 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*CP*CP*C*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
Authors:Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
Deposit date:2007-01-26
Release date:2007-06-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
2EC0
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BU of 2ec0 by Molmil
RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP
Descriptor: 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
Authors:Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
Deposit date:2007-02-09
Release date:2007-06-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E9T
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BU of 2e9t by Molmil
Foot-and-mouth disease virus RNA-polymerase RNA dependent in complex with a template-primer RNA and 5F-UTP
Descriptor: 5'-R(*GP*GP*GP*CP*CP*CP*(5FU))-3', 5'-R(P*UP*AP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ...
Authors:Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
Deposit date:2007-01-26
Release date:2007-06-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
3ZUE
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BU of 3zue by Molmil
Rabbit Hemorrhagic Disease Virus (RHDV)capsid protein
Descriptor: CAPSID STRUCTURAL PROTEIN VP60
Authors:Luque, D, Gonzalez, J.M, Gomez-Blanco, J, Marabini, R, Chichon, J, Mena, I, Angulo, I, Carrascosa, J.L, Verdaguer, N, Trus, B.L, Barcena, J, Caston, J.R.
Deposit date:2011-07-18
Release date:2012-05-23
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (10.3 Å)
Cite:Epitope Insertion at the N-Terminal Molecular Switch of the Rabbit Hemorrhagic Disease Virus T=3 Capsid Protein Leads to Larger T=4 Capsids.
J.Virol., 86, 2012
6I7P
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BU of 6i7p by Molmil
Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033)
Descriptor: NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N.
Deposit date:2018-11-16
Release date:2019-04-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.975 Å)
Cite:Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
5CX6
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BU of 5cx6 by Molmil
Crystal structure of Thosea asigna virus RNA-dependent RNA polymerase (RdRP) complexed with CDP
Descriptor: CYTIDINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
Authors:Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N.
Deposit date:2015-07-28
Release date:2015-11-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases.
Plos Pathog., 11, 2015

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