Author results

2F23
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CRYSTAL STRUCTURE OF GREA FACTOR HOMOLOG 1 (GFH1) PROTEIN OF THERMUS THERMOPHILUS
Descriptor:Anti-cleavage anti-greA transcription factor gfh1
Authors:Kong, X.P., Kim, S.-S.
Deposit date:2005-11-15
Release date:2006-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:pH-dependent conformational switch activates the inhibitor of transcription elongation.
Embo J., 25, 2006
3GHB
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CRYSTAL STRUCTURE OF ANTI-HIV-1 FAB 447-52D IN COMPLEX WITH V3 PEPTIDE W2RW020
Descriptor:Fab 447-52D, light chain, heavy chain, ...
Authors:Kong, X.P., Burke, V.J.
Deposit date:2009-03-03
Release date:2009-12-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of the cross-reactivity of genetically related human anti-HIV-1 mAbs: implications for design of V3-based immunogens
Structure, 17, 2009
3GHE
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CRYSTAL STRUCTURE OF ANTI-HIV-1 FAB 537-10D IN COMPLEX WITH V3 PEPTIDE MN
Descriptor:Fab 537-10D, light chain, heavy chain, ...
Authors:Kong, X.P., Burke, V.J.
Deposit date:2009-03-03
Release date:2009-12-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of the cross-reactivity of genetically related human anti-HIV-1 mAbs: implications for design of V3-based immunogens
Structure, 17, 2009
3GO1
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CRYSTAL STRUCTURE OF ANTI-HIV-1 FAB 268-D IN COMPLEX WITH V3 PEPTIDE MN
Descriptor:Fab 268-D, light chain, heavy chain, ...
Authors:Kong, X.P., Burke, V.J.
Deposit date:2009-03-18
Release date:2010-06-23
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
3UJI
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CRYSTAL STRUCTURE OF ANTI-HIV-1 V3 FAB 2558 IN COMPLEX WITH MN PEPTIDE
Descriptor:Light chain of anti-HIV-1 V3 monoclonal antibody 2558, Fab region of the heavy chain of anti-HIV-1 V3 monoclonal antibody 2558, Envelope glycoprotein gp160, ...
Authors:Kong, X.P.
Deposit date:2011-11-07
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure.
Plos One, 6, 2011
3UJJ
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CRYSTAL STRUCTURE OF ANTI-HIV-1 V3 FAB 4025 IN COMPLEX WITH CON A PEPTIDE
Descriptor:Light chain of anti-HIV-1 V3 monoclonal antibody 4025, Fab region of the heavy chain of anti-HIV-1 V3 monoclonal antibody 4025, Gp120, ...
Authors:Kong, X.P., Sampson, J.
Deposit date:2011-11-07
Release date:2011-12-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure.
Plos One, 6, 2011
1HXW
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HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538
Descriptor:HIV-1 PROTEASE, RITONAVIR
Authors:Park, C.H., Nienaber, V., Kong, X.P.
Deposit date:1997-01-24
Release date:1998-02-04
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.
Proc.Natl.Acad.Sci.USA, 92, 1995
1PRO
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HIV-1 PROTEASE DIMER COMPLEXED WITH A-98881
Descriptor:HIV-1 PROTEASE, (5R,6R)-2,4-BIS-(4-HYDROXY-3-METHOXYBENZYL)-1,5-DIBENZYL-3-OXO-6-HYDROXY-1,2,4-TRIAZACYCLOHEPTANE
Authors:Park, C.H., Kong, X.P., Dealwis, C.G.
Deposit date:1995-07-18
Release date:1996-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease.
J.Med.Chem., 39, 1996
3Q6F
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CRYSTAL STRUCTURE OF FAB OF HUMAN MAB 2909 SPECIFIC FOR QUATERNARY NEUTRALIZING EPITOPE OF HIV-1 GP120
Descriptor:Light chain of Fab of human mAb 2909, Heavy chain of Fab of human mAb 2909, DI(HYDROXYETHYL)ETHER
Authors:Spurrier, B., Sampson, J., Totrov, M., Li, H., O'Neal, T., William, C., Robinson, J., Gorny, M.K., Zolla-Pazner, S., Kong, X.P.
Deposit date:2010-12-31
Release date:2011-05-25
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (3.192 Å)
Cite:Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
3Q6G
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CRYSTAL STRUCTURE OF FAB OF RHESUS MAB 2.5B SPECIFIC FOR QUATERNARY NEUTRALIZING EPITOPE OF HIV-1 GP120
Descriptor:Light chain of Fab of rhesus mAb 2.5B, Heavy chain of Fab of rhesus mAb 2.5B
Authors:Spurrier, B., Sampson, J., Totrov, M., Li, H., O'Neal, T., William, C., Robinson, J., Gorny, M.K., Zolla-Pazner, S., Kong, X.P.
Deposit date:2010-12-31
Release date:2011-05-25
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
3RQU
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CRYSTAL STRUCTURE OF A PROKARYOTIC PENTAMERIC LIGAND-GATED ION CHANNEL, ELIC
Descriptor:ELIC Pentameric Ligand Gated Ion Channel from Erwinia Chrysanthemi, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL
Authors:Pan, J.J., Chen, Q., Yoshida, K., Cohen, A., Kong, X.P., Xu, Y., Tang, P.
Deposit date:2011-04-28
Release date:2012-03-07
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (3.089 Å)
Cite:Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine.
Nat Commun, 3, 2012
3RQW
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CRYSTAL STRUCTURE OF ACETYLCHOLINE BOUND TO A PROKARYOTIC PENTAMERIC LIGAND-GATED ION CHANNEL, ELIC
Descriptor:ELIC Pentameric Ligand Gated Ion Channel from Erwinia Chrysanthemi, ACETYLCHOLINE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Pan, J.J., Chen, Q., Yoshida, K., Cohen, A., Kong, X.P., Xu, Y., Tang, P.
Deposit date:2011-04-28
Release date:2012-03-07
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.913 Å)
Cite:Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine.
Nat Commun, 3, 2012
4D9L
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FAB STRUCTURE OF ANTI-HIV-1 GP120 V2 MAB 697
Descriptor:Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697, Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697
Authors:Pan, R.M., Kong, X.P.
Deposit date:2012-01-11
Release date:2012-03-21
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2.485 Å)
Cite:Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals.
Virology, 427, 2012
4F57
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FAB STRUCTURE OF A NEUTRALIZING ANTIBODY L1 FROM AN EARLY SUBTYPE A HIV-1 INFECTED PATIENT
Descriptor:Light chain of Fab of a neutralizing antibody L1, Heavy chain of Fab of a neutralizing antibody L1, GLYCEROL
Authors:Pan, R.M., Kong, X.P.
Deposit date:2012-05-12
Release date:2013-03-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth.
Plos Pathog., 9, 2013
4F58
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FAB STRUCTURE OF A NEUTRALIZING ANTIBODY L3 FROM AN EARLY SUBTYPE A HIV-1 INFECTED PATIENT
Descriptor:Light chain of Fab of a neutralizing antibody L3, Heavy chain of Fab of a neutralizing antibody L3, SULFATE ION
Authors:Pan, R.M., Kong, X.P.
Deposit date:2012-05-12
Release date:2013-03-27
Method:X-RAY DIFFRACTION (2.488 Å)
Cite:Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth.
Plos Pathog., 9, 2013
4F8H
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X-RAY STRUCTURE OF THE ANESTHETIC KETAMINE BOUND TO THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL
Descriptor:Proton-gated ion channel, (R)-ketamine, tetradecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, ...
Authors:Pan, J.J., Chen, Q., Willenbring, D., Kong, X.P., Cohen, A., Xu, Y., Tang, P.
Deposit date:2012-05-17
Release date:2012-08-29
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine.
Structure, 20, 2012
4JO1
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CRYSTAL STRUCTURE OF RABBIT MAB R56 FAB IN COMPLEX WITH V3 CROWN OF HIV-1 JR-FL GP120
Descriptor:monoclonal anti-HIV-1 gp120 V3 antibody R56 light chain, monoclonal anti-HIV-1 gp120 V3 antibody R56 heavy chain, gp120, ...
Authors:Pan, R.M., Kong, X.P.
Deposit date:2013-03-16
Release date:2013-07-31
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (2.033 Å)
Cite:Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
4JO2
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CRYSTAL STRUCTURE OF RABBIT MAB R56 FAB IN COMPLEX WITH V3 CROWN OF HIV-1 CONSENSUS A GP120
Descriptor:monoclonal anti-HIV-1 gp120 V3 antibody R56 light chain, monoclonal anti-HIV-1 gp120 V3 antibody R56 heavy chain, gp120, ...
Authors:Pan, R.M., Kong, X.P.
Deposit date:2013-03-16
Release date:2013-07-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
4JO3
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CRYSTAL STRUCTURE OF RABBIT MAB R20 FAB IN COMPLEX WITH V3 C-TERMINUS OF HIV-1 CONSENSUS B GP120
Descriptor:monoclonal anti-HIV-1 gp120 V3 antibody R20 light chain, monoclonal anti-HIV-1 gp120 V3 antibody R20 heavy chain, gp120, ...
Authors:Pan, R.M., Kong, X.P.
Deposit date:2013-03-16
Release date:2013-07-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
4JO4
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CRYSTAL STRUCTURE OF RABBIT MAB R20 FAB
Descriptor:monoclonal anti-HIV-1 gp120 V3 antibody R20 light chain, monoclonal anti-HIV-1 gp120 V3 antibody R20 heavy chain, PENTAETHYLENE GLYCOL, ...
Authors:Pan, R.M., Kong, X.P.
Deposit date:2013-03-16
Release date:2013-07-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
4M1D
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CRYSTAL STRUCTURE OF ANTI-HIV-1 FAB 447-52D IN COMPLEX WITH V3 CYCLIC PEPTIDE MN
Descriptor:Fab mAb 447-52D Light Chain, Fab mAb 447-52D Heavy Chain, Cyclic V3 Arch Peptide, ...
Authors:Killikelly, A., Kong, X.P.
Deposit date:2013-08-02
Release date:2013-09-04
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Thermodynamic Signatures of the Antigen Binding Site of mAb 447-52D Targeting the Third Variable Region of HIV-1 gp120.
Biochemistry, 52, 2013
4OAW
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FAB STRUCTURE OF ANTI-HIV GP120 V2 MAB 2158
Descriptor:Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 2158, Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 2158, SULFATE ION, ...
Authors:Spurrier, B.R., Kong, X.P.
Deposit date:2014-01-06
Release date:2014-03-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Functional Implications of the Binding Mode of a Human Conformation-Dependent V2 Monoclonal Antibody against HIV.
J.Virol., 88, 2014
2POL
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THREE-DIMENSIONAL STRUCTURE OF THE BETA SUBUNIT OF ESCHERICHIA COLI DNA POLYMERASE III HOLOENZYME: A SLIDING DNA CLAMP
Descriptor:DNA POLYMERASE III (BETA SUBUNIT)
Authors:Kong, X.-P., Kuriyan, J.
Deposit date:1992-11-13
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of the beta subunit of E. coli DNA polymerase III holoenzyme: a sliding DNA clamp.
Cell(Cambridge,Mass.), 69, 1992
1PLQ
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CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA
Descriptor:PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA), MERCURY (II) ION
Authors:Krishna, T.S.R., Kong, X.-P., Gary, S., Burgers, P.M., Kuriyan, J.
Deposit date:1995-01-02
Release date:1995-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
Cell(Cambridge,Mass.), 79, 1994
1PLR
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CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA
Descriptor:PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
Authors:Krishna, T.S.R., Kong, X.-P., Gary, S., Burgers, P.M., Kuriyan, J.
Deposit date:1995-01-02
Release date:1995-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
Cell(Cambridge,Mass.), 79, 1994
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