Author results

3T3M
  • Download 3t3m
  • View 3t3m
Molmil generated image of 3t3m
A NOVEL HIGH AFFINITY INTEGRIN ALPHAIIBBETA3 RECEPTOR ANTAGONIST THAT UNEXPECTEDLY DISPLACES MG2+ FROM THE BETA3 MIDAS
分子名称:Integrin alpha-IIb, Integrin beta-3, Monoclonal antibody 10E5 heavy chain, ...
著者Zhu, J., Zhu, J., Springer, T.A.
登録日2011-07-25
公開日2012-03-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS
Sci Transl Med, 4, 2012
3T3P
  • Download 3t3p
  • View 3t3p
Molmil generated image of 3t3p
A NOVEL HIGH AFFINITY INTEGRIN ALPHAIIBBETA3 RECEPTOR ANTAGONIST THAT UNEXPECTEDLY DISPLACES MG2+ FROM THE BETA3 MIDAS
分子名称:Integrin alpha-IIb, Integrin beta-3, Monoclonal antibody 10E5 heavy chain, ...
著者Zhu, J., Zhu, J., Springer, T.A.
登録日2011-07-25
公開日2012-03-28
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS
Sci Transl Med, 4, 2012
4UIK
  • Download 4uik
  • View 4uik
Molmil generated image of 4uik
CRYSTAL STRUCTURE OF QUININE-DEPENDENT FAB 314.1
分子名称:FAB 314.1
著者Zhu, J., Zhu, J., Bougie, D.W., Aster, R.H., Springer, T.A.
登録日2015-03-30
公開日2015-09-02
最終更新日2015-11-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin Alphaiib Beta3
Blood, 126, 2015
4UIL
  • Download 4uil
  • View 4uil
Molmil generated image of 4uil
CRYSTAL STRUCTURE OF QUININE-DEPENDENT FAB 314.1 WITH QUININE
分子名称:FAB 314.1, Quinine
著者Zhu, J., Zhu, J., Bougie, D.W., Aster, R.H., Springer, T.A.
登録日2015-03-30
公開日2015-09-02
最終更新日2015-11-11
実験手法X-RAY DIFFRACTION (2.853 Å)
主引用文献Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin Alphaiib Beta3
Blood, 126, 2015
4UIM
  • Download 4uim
  • View 4uim
Molmil generated image of 4uim
CRYSTAL STRUCTURE OF QUININE-DEPENDENT FAB 314.3
分子名称:FAB 314.3, SULFATE ION
著者Zhu, J., Zhu, J., Bougie, D.W., Aster, R.H., Springer, T.A.
登録日2015-03-30
公開日2015-09-02
最終更新日2015-11-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin Alphaiib Beta3
Blood, 126, 2015
4UIN
  • Download 4uin
  • View 4uin
Molmil generated image of 4uin
CRYSTAL STRUCTURE OF QUININE-DEPENDENT FAB 314.3 WITH QUININE
分子名称:FAB 314.3, Quinine
著者Zhu, J., Zhu, J., Bougie, D.W., Aster, R.H., Springer, T.A.
登録日2015-03-30
公開日2015-09-02
最終更新日2017-04-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Quinine-Dependent Antibody Binding to Platelet Integrin Alphaiib Beta3
Blood, 126, 2015
5YPR
  • Download 5ypr
  • View 5ypr
Molmil generated image of 5ypr
CRYSTAL STRUCTURE OF PSD-95 SH3-GK DOMAIN IN COMPLEX WITH A SYNTHESIZED INHIBITOR
分子名称:Disks large homolog 4, Synthesized GK inhibitor
著者Zhu, J., Zhou, Q., Shang, Y., Weng, Z., Zhu, R., Zhang, M.
登録日2017-11-02
公開日2018-03-14
実験手法X-RAY DIFFRACTION (2.349 Å)
主引用文献Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.
Cell Rep, 21, 2017
5EWD
  • Download 5ewd
  • View 5ewd
Molmil generated image of 5ewd
CRYSTAL STRUCTURE OF THE HUMAN BRPF1 BROMODOMAIN IN COMPLEX WITH SEED18
分子名称:Peregrin, 4-phenylpyridine, NITRATE ION
著者Zhu, J., Caflisch, A.
登録日2015-11-20
公開日2016-05-25
最終更新日2016-06-22
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59, 2016
5MME
  • Download 5mme
  • View 5mme
Molmil generated image of 5mme
CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXD WITH US46C
分子名称:CREB-binding protein, dimethyl 5-[(5-ethanoyl-2-ethoxy-phenyl)amino]benzene-1,3-dicarboxylate
著者Zhu, J., Caflisch, A.
登録日2016-12-09
公開日2017-12-20
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
2IEL
  • Download 2iel
  • View 2iel
Molmil generated image of 2iel
CRYSTAL STRUCTURE OF TT0030 FROM THERMUS THERMOPHILUS
分子名称:Hypothetical Protein TT0030
著者Zhu, J., Huang, J., Stepanyuk, G., Chen, L., Chang, J., Zhao, M., Xu, H., Liu, Z.J., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2006-09-19
公開日2006-11-14
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus AT 1.6 ANGSTROMS RESOLUTION
To be Published
2QVO
  • Download 2qvo
  • View 2qvo
Molmil generated image of 2qvo
CRYSTAL STRUCTURE OF AF1382 FROM ARCHAEOGLOBUS FULGIDUS
分子名称:Uncharacterized protein AF_1382
著者Zhu, J., Zhao, M., Fu, Z.-Q., Yang, H., Chang, J., Hao, X., Chen, L., Liu, Z.J., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
登録日2007-08-08
公開日2007-09-04
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of AF1382 from Archaeoglobus fulgidus.
To be Published
3WP0
  • Download 3wp0
  • View 3wp0
Molmil generated image of 3wp0
CRYSTAL STRUCTURE OF DLG GK IN COMPLEX WITH A PHOSPHOR-LGL2 PEPTIDE
分子名称:Disks large homolog 4, Lethal(2) giant larvae protein homolog 2, GLYCEROL
著者Zhu, J., Shang, Y., Wan, Q., Xia, Y., Chen, J., Du, Q., Zhang, M.
登録日2014-01-08
公開日2014-03-19
最終更新日2014-04-30
実験手法X-RAY DIFFRACTION (2.039 Å)
主引用文献Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
Cell Res., 24, 2014
3WP1
  • Download 3wp1
  • View 3wp1
Molmil generated image of 3wp1
PHOSPHORYLATION-DEPENDENT INTERACTION BETWEEN TUMOR SUPPRESSORS DLG AND LGL
分子名称:Disks large homolog 4, Lethal(2) giant larvae protein homolog 2, SULFATE ION
著者Zhu, J., Shang, Y., Wan, Q., Xia, Y., Chen, J., Du, Q., Zhang, M.
登録日2014-01-08
公開日2014-03-19
最終更新日2014-04-30
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
Cell Res., 24, 2014
5COD
  • Download 5cod
  • View 5cod
Molmil generated image of 5cod
BOVINE HEART COMPLEX I MEMBRANE DOMAIN
分子名称:NADH-ubiquinone oxidoreductase chain 5, NADH-ubiquinone oxidoreductase chain 4, Unknown structure, ...
著者Zhu, J., Hirst, J., King, M.S., Yu, M., Leslie, A.G.W., Klipcan, L.
登録日2015-07-20
公開日2015-09-23
最終更新日2015-10-07
実験手法X-RAY DIFFRACTION (6.74 Å)
主引用文献Structure of subcomplex I beta of mammalian respiratory complex I leads to new supernumerary subunit assignments.
Proc.Natl.Acad.Sci.USA, 112, 2015
5MMG
  • Download 5mmg
  • View 5mmg
Molmil generated image of 5mmg
CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXED WITH UT07C
分子名称:CREB-binding protein, 1-[4-ethoxy-3-[(1-methylsulfonylindol-6-yl)amino]phenyl]ethanone
著者Zhu, J., Caflisch, A.
登録日2016-12-09
公開日2017-12-20
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5MPK
  • Download 5mpk
  • View 5mpk
Molmil generated image of 5mpk
CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXED WITH DK19
分子名称:CREB-binding protein, ~{N}-(5-ethanoyl-2-ethoxy-phenyl)-3-(2~{H}-1,2,3,4-tetrazol-5-yl)-5-(1,3-thiazol-4-yl)benzamide
著者Zhu, J., Caflisch, A.
登録日2016-12-16
公開日2018-01-17
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5MPN
  • Download 5mpn
  • View 5mpn
Molmil generated image of 5mpn
CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXED WITH FA26
分子名称:CREB-binding protein, 1-[4-ethoxy-3-[3-(2~{H}-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]ethanone, 1,2-ETHANEDIOL
著者Zhu, J., Caflisch, A.
登録日2016-12-16
公開日2018-01-17
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
5OWK
  • Download 5owk
  • View 5owk
Molmil generated image of 5owk
CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXED WITH DSPB2A002
分子名称:CREB-binding protein, ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate
著者Zhu, J., Spiliotopoulos, D., Caflisch, A.
登録日2017-09-01
公開日2018-08-29
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
6FQO
  • Download 6fqo
  • View 6fqo
Molmil generated image of 6fqo
CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXD WITH DT29
分子名称:CREB-binding protein, ~{N}-[3-(2,5-dimethyl-3-oxidanylidene-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide, 1,2-ETHANEDIOL
著者Zhu, J., Caflisch, A.
登録日2018-02-14
公開日2018-08-29
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
6FQU
  • Download 6fqu
  • View 6fqu
Molmil generated image of 6fqu
CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXD WITH DR09
分子名称:CREB-binding protein, 1-[3-[3-[3,3-bis(fluoranyl)piperidin-1-yl]phenyl]-4-ethoxy-phenyl]ethanone
著者Zhu, J., Caflisch, A.
登録日2018-02-14
公開日2018-08-29
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
6FR0
  • Download 6fr0
  • View 6fr0
Molmil generated image of 6fr0
CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXD WITH PB08
分子名称:CREB-binding protein, ~{N}-[3-(5-ethanoyl-2-ethoxy-phenyl)-5-(2-ethyl-5-methyl-3-oxidanylidene-1,2-oxazol-4-yl)phenyl]furan-2-carboxamide
著者Zhu, J., Caflisch, A.
登録日2018-02-15
公開日2018-08-29
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
6FRF
  • Download 6frf
  • View 6frf
Molmil generated image of 6frf
CRYSTAL STRUCTURE OF CREBBP BROMODOMAIN COMPLEXD WITH PA10
分子名称:CREB-binding protein, ~{N}-[3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide
著者Zhu, J., Caflisch, A.
登録日2018-02-15
公開日2018-08-29
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Binding Motifs in the CBP Bromodomain: An Analysis of 20 Crystal Structures of Complexes with Small Molecules.
ACS Med Chem Lett, 9, 2018
1ZNN
  • Download 1znn
  • View 1znn
Molmil generated image of 1znn
STRUCTURE OF THE SYNTHASE SUBUNIT OF PLP SYNTHASE
分子名称:PLP SYNTHASE, SULFATE ION, (4R)-2-METHYLPENTANE-2,4-DIOL
著者Zhu, J., Burgner, J.W., Harms, E., Belitsky, B.R., Smith, J.L.
登録日2005-05-11
公開日2005-05-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A New Arrangement of (beta/alpha)8 Barrels in the Synthase Subunit of PLP Synthase.
J.Biol.Chem., 280, 2005
2KBH
  • Download 2kbh
  • View 2kbh
Molmil generated image of 2kbh
SOLUTION STRUCTURE OF BMKALPHATX11 (MAJOR CONFORMATION)
分子名称:Toxin Bmka2
著者Zhu, J., Wu, H.
登録日2008-11-28
公開日2009-12-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of BmKalphaTx11, a toxin from the venom of the Chinese scorpion Buthus martensii Karsch
Biochem.Biophys.Res.Commun., 391, 2010
2KBJ
  • Download 2kbj
  • View 2kbj
Molmil generated image of 2kbj
SOLUTION STRUCTURE OF BMKALPHATX11 (MINOR CONFORMATION)
分子名称:Toxin Bmka2
著者Zhu, J., Wu, H.
登録日2008-11-28
公開日2009-12-08
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of BmKalphaTx11, a toxin from the venom of the Chinese scorpion Buthus martensii Karsch
Biochem.Biophys.Res.Commun., 391, 2010