3F5C
| Structure of Dax-1:LRH-1 complex | Descriptor: | Nuclear receptor subfamily 0 group B member 1, Nuclear receptor subfamily 5 group A member 2 | Authors: | Fletterick, R.J, Sablin, E.P. | Deposit date: | 2008-11-03 | Release date: | 2008-12-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1. Proc.Natl.Acad.Sci.USA, 105, 2008
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1ANC
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1ANB
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1AND
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1ANE
| ANIONIC TRYPSIN WILD TYPE | Descriptor: | ANIONIC TRYPSIN, BENZAMIDINE | Authors: | Fletterick, R.J, Mcgrath, M.E. | Deposit date: | 1994-12-21 | Release date: | 1997-04-01 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of an engineered, metal-actuated switch in trypsin. Biochemistry, 32, 1993
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1EWM
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3CNZ
| Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin heavy chain-like protein, MAGNESIUM ION | Authors: | Vinogradova, M.V, Malanina, G.G, Reddy, V, Reddy, A.S.N, Fletterick, R.J. | Deposit date: | 2008-03-26 | Release date: | 2008-06-17 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein. J.Struct.Biol., 163, 2008
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3LVG
| Crystal structure of a clathrin heavy chain and clathrin light chain complex | Descriptor: | Clathrin heavy chain 1, Clathrin light chain B | Authors: | Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M. | Deposit date: | 2010-02-20 | Release date: | 2010-06-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (7.94 Å) | Cite: | Conformation switching of clathrin light chain regulates clathrin lattice assembly. Dev.Cell, 18, 2010
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3LVH
| Crystal structure of a clathrin heavy chain and clathrin light chain complex | Descriptor: | Clathrin heavy chain 1, Clathrin light chain B | Authors: | Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M. | Deposit date: | 2010-02-20 | Release date: | 2010-06-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (9 Å) | Cite: | Conformation switching of clathrin light chain regulates clathrin lattice assembly. Dev.Cell, 18, 2010
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1NQ0
| TR Receptor Mutations Conferring Hormone Resistance and Reduced Corepressor Release Exhibit Decreased Stability in the Nterminal LBD | Descriptor: | ARSENIC, Thyroid hormone receptor beta-1, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID | Authors: | Huber, B.R, Desclozeaux, M, West, B.L, Cunha-Lima, S.T, Nguyen, H.T, Baxter, J.D, Ingraham, H.A, Fletterick, R.J. | Deposit date: | 2003-01-20 | Release date: | 2003-04-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain Mol.Endocrinol., 17, 2003
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1NQ2
| Two RTH Mutants with Impaired Hormone Binding | Descriptor: | ARSENIC, SODIUM ION, Thyroid hormone receptor beta-1, ... | Authors: | Huber, B.R, Sandler, B, West, B.L, Cunha-Lima, S.T, Nguyen, H.T, Apriletti, J.W, Baxter, J.D, Fletterick, R.J. | Deposit date: | 2003-01-21 | Release date: | 2003-04-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Two resistance to thyroid hormone mutants with impaired hormone binding Mol.Endocrinol., 17, 2003
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1NT3
| HUMAN NEUROTROPHIN-3 | Descriptor: | PROTEIN (NEUROTROPHIN-3) | Authors: | Butte, M.J, Hwang, P.K, Mobley, W.C, Fletterick, R.J. | Deposit date: | 1999-05-17 | Release date: | 1999-06-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors. Biochemistry, 37, 1998
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6DDA
| Nurr1 Covalently Modified by a Dopamine Metabolite | Descriptor: | 5-hydroxy-1,2-dihydro-6H-indol-6-one, BROMIDE ION, Nuclear receptor subfamily 4 group A member 2, ... | Authors: | Bruning, J.M, Wang, Y, Otrabella, F, Boxue, T, Liu, H, Bhattacharya, P, Guo, S, Holton, J.M, Fletterick, R.J, Jacobson, M.P, England, P.M. | Deposit date: | 2018-05-09 | Release date: | 2019-03-20 | Last modified: | 2019-11-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite. Cell Chem Biol, 26, 2019
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2Z4J
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3COB
| Structural Dynamics of the Microtubule binding and regulatory elements in the Kinesin-like Calmodulin binding protein | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin heavy chain-like protein, MAGNESIUM ION | Authors: | Vinogradova, M.V, Malanina, G.G, Reddy, V, Reddy, A.S.N, Fletterick, R.J. | Deposit date: | 2008-03-27 | Release date: | 2008-06-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein. J.Struct.Biol., 163, 2008
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3I00
| Crystal Structure of the huntingtin interacting protein 1 coiled coil domain | Descriptor: | Huntingtin-interacting protein 1 | Authors: | Wilbur, J.D, Hwang, P.K, Brodsky, F.M, Fletterick, R.J. | Deposit date: | 2009-06-24 | Release date: | 2010-02-23 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain. Acta Crystallogr.,Sect.D, 66, 2010
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1YGP
| PHOSPHORYLATED FORM OF YEAST GLYCOGEN PHOSPHORYLASE WITH PHOSPHATE BOUND IN THE ACTIVE SITE. | Descriptor: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, YEAST GLYCOGEN PHOSPHORYLASE | Authors: | Lin, K, Rath, V.L, Dai, S.C, Fletterick, R.J, Hwang, P.K. | Deposit date: | 1996-05-30 | Release date: | 1996-12-23 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A protein phosphorylation switch at the conserved allosteric site in GP. Science, 273, 1996
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2AIM
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3F7D
| SF-1 LBD bound by phosphatidylcholine | Descriptor: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, nuclear receptor SF-1 | Authors: | Sablin, E.P, Fletterick, R.J. | Deposit date: | 2008-11-07 | Release date: | 2008-12-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands. Mol.Endocrinol., 23, 2009
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1SLW
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1SLX
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1SLU
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1SLV
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1YMT
| Mouse SF-1 LBD | Descriptor: | 1-CIS-9-OCTADECANOYL-2-CIS-9-HEXADECANOYL PHOSPHATIDYL GLYCEROL, Nuclear receptor 0B2, Steroidogenic factor 1 | Authors: | Krylova, I.N, Sablin, E.P, Moore, J, Xu, R.X, Waitt, G.M, Juzumiene, D, Bynum, J.M, Fletterick, R.J, Willson, T.M, Ingraham, H.A. | Deposit date: | 2005-01-21 | Release date: | 2005-03-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 Cell(Cambridge,Mass.), 120, 2005
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1XJ7
| Complex Androgen Receptor LBD and RAC3 peptide | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, RAC3 derived peptide | Authors: | Estebanez-Perpina, E, Moore, J.M.R, Mar, E, Nguyen, P, Delgado-Rodrigues, E, Baxter, J.D, Buehrer, B.M, Webb, P, Fletterick, R.J, Guy, R.K. | Deposit date: | 2004-09-22 | Release date: | 2005-01-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor J.Biol.Chem., 280, 2005
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