6DDA
Nurr1 Covalently Modified by a Dopamine Metabolite
Summary for 6DDA
Entry DOI | 10.2210/pdb6dda/pdb |
Descriptor | Nuclear receptor subfamily 4 group A member 2, POTASSIUM ION, 5-hydroxy-1,2-dihydro-6H-indol-6-one, ... (5 entities in total) |
Functional Keywords | nurr1, dopamine, cysteine adduct, dihydroxyindole, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 93240.25 |
Authors | Bruning, J.M.,Wang, Y.,Otrabella, F.,Boxue, T.,Liu, H.,Bhattacharya, P.,Guo, S.,Holton, J.M.,Fletterick, R.J.,Jacobson, M.P.,England, P.M. (deposition date: 2018-05-09, release date: 2019-03-20, Last modification date: 2019-11-06) |
Primary citation | Bruning, J.M.,Wang, Y.,Oltrabella, F.,Tian, B.,Kholodar, S.A.,Liu, H.,Bhattacharya, P.,Guo, S.,Holton, J.M.,Fletterick, R.J.,Jacobson, M.P.,England, P.M. Covalent Modification and Regulation of the Nuclear Receptor Nurr1 by a Dopamine Metabolite. Cell Chem Biol, 26:674-685.e6, 2019 Cited by PubMed: 30853418DOI: 10.1016/j.chembiol.2019.02.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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