Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4JTA
DownloadVisualize
BU of 4jta by Molmil
Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ...
Authors:MacKinnon, R, Banerjee, A, Lee, A, Campbell, E.
Deposit date:2013-03-23
Release date:2013-06-12
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
6V00
DownloadVisualize
BU of 6v00 by Molmil
structure of human KCNQ1-KCNE3-CaM complex
Descriptor: CALCIUM ION, Calmodulin-1, MCherry fluorescent protein,Potassium voltage-gated channel subfamily E member 3, ...
Authors:Mackinnon, R, Sun, J.
Deposit date:2019-11-16
Release date:2019-12-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Basis of Human KCNQ1 Modulation and Gating.
Cell, 180, 2020
6V01
DownloadVisualize
BU of 6v01 by Molmil
structure of human KCNQ1-KCNE3-CaM complex with PIP2
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily E member 3, ...
Authors:Mackinnon, R, Sun, J.
Deposit date:2019-11-18
Release date:2019-12-04
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis of Human KCNQ1 Modulation and Gating.
Cell, 180, 2020
6UZZ
DownloadVisualize
BU of 6uzz by Molmil
structure of human KCNQ1-CaM complex
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1
Authors:Mackinnon, R, Sun, J.
Deposit date:2019-11-16
Release date:2019-12-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Basis of Human KCNQ1 Modulation and Gating.
Cell, 180, 2020
5VMS
DownloadVisualize
BU of 5vms by Molmil
CryoEM structure of Xenopus KCNQ1 channel
Descriptor: CALCIUM ION, Calmodulin, Potassium voltage-gated channel subfamily KQT member 1
Authors:Mackinnon, R, Sun, J.
Deposit date:2017-04-28
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.
Cell, 169, 2017
5TJ6
DownloadVisualize
BU of 5tj6 by Molmil
Ca2+ bound aplysia Slo1
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, High conductance calcium-activated potassium channel, ...
Authors:MacKinnon, R, Tao, X, Hite, R.K.
Deposit date:2016-10-03
Release date:2016-12-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of the open high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
5TJI
DownloadVisualize
BU of 5tji by Molmil
Ca2+ bound aplysia Slo1
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, High conductance calcium-activated potassium channel
Authors:MacKinnon, R, Tao, X, Hite, R.K.
Deposit date:2016-10-04
Release date:2016-12-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for gating the high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
1S5H
DownloadVisualize
BU of 1s5h by Molmil
Potassium Channel Kcsa-Fab Complex T75C mutant in K+
Descriptor: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, DIACYL GLYCEROL, ...
Authors:Mackinnon, R, Zhou, M.
Deposit date:2004-01-20
Release date:2004-05-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution.
J.Mol.Biol., 338, 2004
6PBY
DownloadVisualize
BU of 6pby by Molmil
Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound to calmodulin (conformation 1)
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
Authors:Whicher, J.R, MacKinnon, R.
Deposit date:2019-06-14
Release date:2019-09-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Regulation of Eag1 gating by its intracellular domains.
Elife, 8, 2019
1N9P
DownloadVisualize
BU of 1n9p by Molmil
Crystal Structure of the Cytoplasmic Domain of G-protein Activated Inward Rectifier Potassium Channel 1
Descriptor: G protein-activated inward rectifier potassium channel 1
Authors:Nishida, M, MacKinnon, R.
Deposit date:2002-11-26
Release date:2003-01-07
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Inward Rectification: Cytoplasmic Pore of the G Protein-Gated Inward Rectifier GIRK1 at 1.8 A Resolution
Cell(Cambridge,Mass.), 111, 2002
3LNM
DownloadVisualize
BU of 3lnm by Molmil
F233W mutant of the Kv2.1 paddle-Kv1.2 chimera channel
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, F233W mutant of the Kv2.1 paddle-Kv1.2 chimera, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Tao, X, Lee, A, Limapichat, W, Dougherty, D.A, MacKinnon, R.
Deposit date:2010-02-02
Release date:2010-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A gating charge transfer center in voltage sensors.
Science, 328, 2010
5K7L
DownloadVisualize
BU of 5k7l by Molmil
Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calmodulin, ...
Authors:Whicher, J.R, MacKinnon, R.
Deposit date:2016-05-26
Release date:2016-08-17
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structure of the voltage-gated K+ channel Eag1 reveals an alternative voltage sensing mechanism.
Science, 353, 2016
6CNN
DownloadVisualize
BU of 6cnn by Molmil
Cryo-EM structure of the human SK4/calmodulin channel complex in the Ca2+ bound state I
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, Calmodulin-1, ...
Authors:Lee, C.H, MacKinnon, R.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.
Science, 360, 2018
5A6E
DownloadVisualize
BU of 5a6e by Molmil
Cryo-EM structure of the Slo2.2 Na-activated K channel
Descriptor: GATING RING OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, ...
Authors:Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R.
Deposit date:2015-06-25
Release date:2015-10-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel
Nature, 527, 2015
6COY
DownloadVisualize
BU of 6coy by Molmil
Human CLC-1 chloride ion channel, transmembrane domain
Descriptor: CHLORIDE ION, Chloride channel protein 1
Authors:Park, E, MacKinnon, R.
Deposit date:2018-03-13
Release date:2018-06-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structure of the CLC-1 chloride channel fromHomo sapiens.
Elife, 7, 2018
6CNO
DownloadVisualize
BU of 6cno by Molmil
Cryo-EM structure of the human SK4/calmodulin channel complex in the Ca2+ bound state II
Descriptor: CALCIUM ION, Calmodulin-1, Intermediate conductance calcium-activated potassium channel protein 4
Authors:Lee, C.H, MacKinnon, R.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.
Science, 360, 2018
6CNM
DownloadVisualize
BU of 6cnm by Molmil
Cryo-EM structure of the human SK4/calmodulin channel complex
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calmodulin-1, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Lee, C.H, MacKinnon, R.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.
Science, 360, 2018
6COZ
DownloadVisualize
BU of 6coz by Molmil
Human CLC-1 chloride ion channel, C-terminal cytosolic domain
Descriptor: Chloride channel protein 1
Authors:Park, E, MacKinnon, R.
Deposit date:2018-03-13
Release date:2018-06-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structure of the CLC-1 chloride channel fromHomo sapiens.
Elife, 7, 2018
5A6G
DownloadVisualize
BU of 5a6g by Molmil
Cryo-EM structure of the Slo2.2 Na-activated K channel
Descriptor: PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, S1-S4 DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1
Authors:Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R.
Deposit date:2015-06-25
Release date:2015-10-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel
Nature, 527, 2015
5A6F
DownloadVisualize
BU of 5a6f by Molmil
Cryo-EM structure of the Slo2.2 Na-activated K channel
Descriptor: GATING RING OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1
Authors:Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R.
Deposit date:2015-06-25
Release date:2015-10-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel
Nature, 527, 2015
8UQO
DownloadVisualize
BU of 8uqo by Molmil
PLCb3-Gbg-Gaq complex on membranes
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Falzone, M.E, MacKinnon, R.
Deposit date:2023-10-24
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:The mechanism of G alpha q regulation of PLC beta 3 -catalyzed PIP2 hydrolysis.
Proc.Natl.Acad.Sci.USA, 120, 2023
8UQN
DownloadVisualize
BU of 8uqn by Molmil
PLCb3-Gaq complex on membranes
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Falzone, M.E, MacKinnon, R.
Deposit date:2023-10-24
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The mechanism of G alpha q regulation of PLC beta 3 -catalyzed PIP2 hydrolysis.
Proc.Natl.Acad.Sci.USA, 120, 2023
4WFH
DownloadVisualize
BU of 4wfh by Molmil
Human TRAAK K+ channel in a Tl+ bound nonconductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Brohawn, S.G, MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFE
DownloadVisualize
BU of 4wfe by Molmil
Human TRAAK K+ channel in a K+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Brohawn, S.G, MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFG
DownloadVisualize
BU of 4wfg by Molmil
Human TRAAK K+ channel in a Tl+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Brohawn, S.G, MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014

225399

PDB entries from 2024-09-25

PDB statisticsPDBj update infoContact PDBjnumon