3URD
| T181A mutant of alpha-Lytic Protease | Descriptor: | Alpha-lytic protease, GLYCEROL, SULFATE ION | Authors: | Kelch, B.A, Agard, D.A. | Deposit date: | 2011-11-22 | Release date: | 2012-05-23 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Functional modulation of a protein folding landscape via side-chain distortion. Proc.Natl.Acad.Sci.USA, 109, 2012
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3U5Z
| Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | Authors: | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | Deposit date: | 2011-10-11 | Release date: | 2012-01-04 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
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3U60
| Structure of T4 Bacteriophage Clamp Loader Bound To Open Clamp, DNA and ATP Analog | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | Authors: | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | Deposit date: | 2011-10-11 | Release date: | 2012-01-04 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
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3U61
| Structure of T4 Bacteriophage Clamp Loader Bound To Closed Clamp, DNA and ATP Analog and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | Authors: | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | Deposit date: | 2011-10-11 | Release date: | 2012-01-04 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
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3URE
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3URC
| T181G mutant of alpha-Lytic Protease | Descriptor: | Alpha-lytic protease, GLYCEROL, SULFATE ION | Authors: | Kelch, B.A, Agard, D.A. | Deposit date: | 2011-11-22 | Release date: | 2012-05-23 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Functional modulation of a protein folding landscape via side-chain distortion. Proc.Natl.Acad.Sci.USA, 109, 2012
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2OUA
| Crystal Structure of Nocardiopsis Protease (NAPase) | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, GLYCEROL, ... | Authors: | Kelch, B.A, Agard, D.A. | Deposit date: | 2007-02-09 | Release date: | 2007-02-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and mechanistic exploration of Acid resistance: kinetic stability facilitates evolution of extremophilic behavior J.Mol.Biol., 368, 2007
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2PFE
| Crystal Structure of Thermobifida fusca Protease A (TFPA) | Descriptor: | 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, Alkaline serine protease, GLYCEROL, ... | Authors: | Kelch, B.A, Agard, D.A. | Deposit date: | 2007-04-04 | Release date: | 2007-07-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.436 Å) | Cite: | Mesophile versus Thermophile: Insights Into the Structural Mechanisms of Kinetic Stability J.Mol.Biol., 370, 2007
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6D0Q
| Structure of a DNA retention-prone PCNA variant | Descriptor: | Proliferating cell nuclear antigen | Authors: | Kelch, B.A, Gaubitz, C. | Deposit date: | 2018-04-10 | Release date: | 2019-05-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.80051017 Å) | Cite: | Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex. Nucleic Acids Res., 47, 2019
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6D0R
| Structure of a DNA retention-prone PCNA variant | Descriptor: | Proliferating cell nuclear antigen | Authors: | Kelch, B.A, Gaubitz, C. | Deposit date: | 2018-04-10 | Release date: | 2019-05-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.85856962 Å) | Cite: | Effective mismatch repair depends on timely control of PCNA retention on DNA by the Elg1 complex. Nucleic Acids Res., 47, 2019
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6VVO
| Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A. | Deposit date: | 2020-02-18 | Release date: | 2020-02-26 | Last modified: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism Biorxiv, 2020
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6BL5
| Head decoration protein from the hyperthermophilic phage P74-26 | Descriptor: | Head decoration protein | Authors: | Stone, N.P, Hilbert, B.J, Hidalgo, D, Halloran, K.T, Kelch, B.A. | Deposit date: | 2017-11-09 | Release date: | 2018-02-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | A Hyperthermophilic Phage Decoration Protein Suggests Common Evolutionary Origin with Herpesvirus Triplex Proteins and an Anti-CRISPR Protein. Structure, 26, 2018
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6O3H
| Icosahedral reconstruction of the thermophilic bacteriophage P74-26 capsid | Descriptor: | Major head protein, P74-26 Head Decoration Protein | Authors: | Stone, N.P, Demo, G, Agnello, E, Kelch, B.A. | Deposit date: | 2019-02-26 | Release date: | 2019-07-24 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure. Nat Commun, 10, 2019
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5TGE
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8E84
| Human PCNA mutant- C148S | Descriptor: | Proliferating cell nuclear antigen | Authors: | Magrino, J, Page, B, Gaubitz, C, Kelch, B.A. | Deposit date: | 2022-08-25 | Release date: | 2023-04-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder. J.Biol.Chem., 299, 2023
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6V1I
| Cryo-EM reconstruction of the thermophilic bacteriophage P74-26 small terminase- symmetric | Descriptor: | Small terminase protein | Authors: | Hayes, J.A, Hilbert, B.J, Gaubitz, C, Stone, N.P, Kelch, B.A. | Deposit date: | 2019-11-20 | Release date: | 2020-02-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | A thermophilic phage uses a small terminase protein with a fixed helix-turn-helix geometry. J.Biol.Chem., 295, 2020
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7KS4
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5E0U
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5E0V
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5E0T
| Human PCNA mutant - S228I | Descriptor: | Proliferating cell nuclear antigen | Authors: | Duffy, C.M, Hilbert, B.J, Kelch, B.A. | Deposit date: | 2015-09-29 | Release date: | 2016-04-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6653 Å) | Cite: | A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428, 2016
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8VAP
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8VAR
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8VAQ
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8VAL
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8VAS
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