8A53
 
 | | Crystal structure of AtMCA-IIf C147A (metacaspase 9) from Arabidopsis thaliana | | 分子名称: | Metacaspase-9, NITRATE ION | | 著者 | Sabljic, I, Stael, S, Stahlberg, J, Bozhkov, P. | | 登録日 | 2022-06-14 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure-function study of a Ca 2+ -independent metacaspase involved in lateral root emergence.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7JL7
 | | Zebrafish Caspase N213T | | 分子名称: | ASP-GLU-VAL-ASP peptide, Caspase 3, apoptosis-related cysteine protease a | | 著者 | Clark, A.C, Swartz, P.D. | | 登録日 | 2020-07-29 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Remodeling hydrogen bond interactions results in relaxed specificity of Caspase-3.
Biosci.Rep., 41, 2021
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2AR9
 | | Crystal structure of a dimeric caspase-9 | | 分子名称: | Caspase-9, D-MALATE | | 著者 | Chao, Y, Shiozaki, E.N, Srinivassula, S.M, Rigotti, D.J, Fairman, R, Shi, Y. | | 登録日 | 2005-08-19 | | 公開日 | 2005-10-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Engineering a Dimeric Caspase-9: A Re-Evaluation of the Induced Proximity Model for Caspase Activation
PLOS BIOL., 3, 2005
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6PZP
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6PX9
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1BMQ
 | | CRYSTAL STRUCTURE OF THE COMPLEX OF INTERLEUKIN-1BETA CONVERTING ENZYME (ICE) WITH A PEPTIDE BASED INHIBITOR, (3S )-N-METHANESULFONYL-3-({1-[N-(2-NAPHTOYL)-L-VALYL]-L-PROLYL }AMINO)-4-OXOBUTANAMIDE | | 分子名称: | (3S)-N-METHANESULFONYL-3-({1-[N-(2-NAPHTOYL)-L-VALYL]-L-PROLYL}AMINO)-4-OXOBUTANAMIDE, PROTEIN (INTERLEUKIN-1 BETA CONVERTASE) | | 著者 | Okamoto, Y, Anan, H, Nakai, E, Morihira, K, Yonetoku, Y, Kurihara, H, Katayama, N, Sakashita, H, Terai, Y, Takeuchi, M, Shibanuma, T, Isomura, Y. | | 登録日 | 1998-07-24 | | 公開日 | 1998-07-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Peptide based interleukin-1 beta converting enzyme (ICE) inhibitors: synthesis, structure activity relationships and crystallographic study of the ICE-inhibitor complex.
Chem.Pharm.Bull., 47, 1999
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8WRA
 | | The Crystal Structure of CASP1 from Biortus | | 分子名称: | 1,2-ETHANEDIOL, Caspase-1 | | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Guo, S. | | 登録日 | 2023-10-13 | | 公開日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The Crystal Structure of CASP1 from Biortus.
To Be Published
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1CP3
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5V6Z
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5V6U
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5JFT
 | | Zebra Fish Caspase-3 | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACE-ASP-GLU-VAL-ASK, ... | | 著者 | Tucker, M.B, MacKenzie, S.H, Maciag, J.J, Dirscherl, H, Swartz, P.D, Yoder, J.A, Hamilton, P.T, Clark, A.C. | | 登録日 | 2016-04-19 | | 公開日 | 2016-10-26 | | 最終更新日 | 2016-11-02 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish.
Protein Sci., 25, 2016
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5K20
 | | Caspase-7 S239E Phosphomimetic | | 分子名称: | Caspase-7 large subunit, Caspase-7 small subunit, FORMIC ACID | | 著者 | Eron, S.J, Hardy, J.A. | | 登録日 | 2016-05-18 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | PAK2 Phosphorylation Inhibits Caspase-7 by Two Divergent Mechanisms: Slowing Activation and Blocking Substrate Binding
To Be Published
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6W8S
 | | Crystal structure of metacaspase 4 from Arabidopsis | | 分子名称: | Metacaspase-4, SULFATE ION | | 著者 | Zhu, P, Yu, X.H, Wang, C, Zhang, Q, Liu, W, McSweeney, S, Shanklin, J, Lam, E, Liu, Q. | | 登録日 | 2020-03-21 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.484 Å) | | 主引用文献 | Structural basis for Ca2+-dependent activation of a plant metacaspase.
Nat Commun, 11, 2020
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5MTK
 | | Crystal structure of human Caspase-1 with (3S,6S,10aS)-N-((2S,3S)-2-hydroxy-5-oxotetrahydrofuran-3-yl)-6-(isoquinoline-1-carboxamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide (PGE-3935199) | | 分子名称: | (3~{S})-3-[[(3~{S},6~{S},10~{a}~{S})-6-(isoquinolin-1-ylcarbonylamino)-5-oxidanylidene-2,3,6,7,8,9,10,10~{a}-octahydro-1~{H}-pyrrolo[1,2-a]azocin-3-yl]carbonylamino]-4-oxidanyl-butanoic acid, Caspase-1 | | 著者 | Brethon, A, Chantalat, L, Christin, O, Clary, L, Fournier, J.F, Gastreich, M, Harris, C, Pascau, J, Isabet, T, Rodeschin, V, Thoreau, E, Roche, D. | | 登録日 | 2017-01-09 | | 公開日 | 2018-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Playing against the odds: scaffold hopping from 3D-fragments
To Be Published
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6W8T
 | | Crystal structure of metacaspase 4 from Arabidopsis (microcrystals treated with calcium) | | 分子名称: | Metacaspase-4, SULFATE ION | | 著者 | Zhu, P, Yu, X.H, Wang, C, Zhang, Q, Liu, W, McSweeney, S, Shanklin, J, Lam, E, Liu, Q. | | 登録日 | 2020-03-21 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for Ca2+-dependent activation of a plant metacaspase.
Nat Commun, 11, 2020
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5MMV
 | | Crystal structure of human Caspase-1 with 2-((2-naphthoyl)-L-valyl)-4-hydroxy-N-((3S)-2-hydroxy-5-oxotetrahydrofuran-3-yl)-2-azabicyclo[2.2.2]octane-3-carboxamide (Compound 1) | | 分子名称: | (3~{S})-3-[[(3~{S})-2-[(2~{S})-3-methyl-2-(naphthalen-2-ylcarbonylamino)butanoyl]-4-oxidanyl-2-azabicyclo[2.2.2]octan-3-yl]carbonylamino]-4-oxidanyl-butanoic acid, Caspase-1 | | 著者 | Brethon, A, Chantalat, L, Christin, O, Clary, L, Fournier, J.F, Gastreich, M, Harris, C, Pascau, J, Isabet, T, Rodeschin, V, Thoreau, E, Roche, D. | | 登録日 | 2016-12-12 | | 公開日 | 2017-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of human Caspase-1 with 2-((2-naphthoyl)-L-valyl)-4-hydroxy-N-((3S)-2-hydroxy-5-oxotetrahydrofuran-3-yl)-2-azabicyclo[2.2.2]octane-3-carboxamide (Compound 1)
To Be Published
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6W8R
 | | Crystal structure of metacaspase 4 C139A from Arabidopsis | | 分子名称: | Metacaspase-4, SULFATE ION | | 著者 | Zhu, P, Yu, X.H, Wang, C, Zhang, Q, Liu, W, McSweeney, S, Shanklin, J, Lam, E, Liu, Q. | | 登録日 | 2020-03-21 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | Structural basis for Ca2+-dependent activation of a plant metacaspase.
Nat Commun, 11, 2020
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2J31
 | | The Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of(Pro)caspase-3 | | 分子名称: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, CASPASE-3 | | 著者 | Feeney, B, Pop, C, Swartz, P, Mattos, C, Clark, A.C. | | 登録日 | 2006-08-17 | | 公開日 | 2006-11-08 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)Caspase-3.
Biochemistry, 45, 2006
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2J32
 | | The Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of(Pro)caspase-3 | | 分子名称: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, CASPASE-3 | | 著者 | Feeney, B, Pop, C, Swartz, P, Mattos, C, Clark, A.C. | | 登録日 | 2006-08-17 | | 公開日 | 2006-11-08 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)Caspase-3.
Biochemistry, 45, 2006
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2J30
 | | The Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)caspase-3 | | 分子名称: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, CASPASE-3 | | 著者 | Feeney, B, Pop, C, Swartz, P, Mattos, C, Clark, A.C. | | 登録日 | 2006-08-17 | | 公開日 | 2006-11-08 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)Caspase-3.
Biochemistry, 45, 2006
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2J33
 | | The Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)caspase-3 | | 分子名称: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, CASPASE-3 | | 著者 | Feeney, B, Pop, C, Swartz, P, Mattos, C, Clark, A.C. | | 登録日 | 2006-08-17 | | 公開日 | 2006-11-08 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)Caspase-3.
Biochemistry, 45, 2006
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2K7Z
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2NN3
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4ZVR
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4ZVT
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