2DGL
| Crystal structure of Escherichia coli GadB in complex with bromide | Descriptor: | ACETIC ACID, BROMIDE ION, Glutamate decarboxylase beta, ... | Authors: | Gruetter, M.G, Capitani, G, Gut, H. | Deposit date: | 2006-03-14 | Release date: | 2006-06-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB Embo J., 25, 2006
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2DGM
| Crystal structure of Escherichia coli GadB in complex with iodide | Descriptor: | ACETIC ACID, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... | Authors: | Gruetter, M.G, Capitani, G, Gut, H. | Deposit date: | 2006-03-14 | Release date: | 2006-06-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB Embo J., 25, 2006
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2DGK
| Crystal structure of an N-terminal deletion mutant of Escherichia coli GadB in an autoinhibited state (aldamine) | Descriptor: | 1,2-ETHANEDIOL, Glutamate decarboxylase beta, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Gruetter, M.G, Capitani, G, Gut, H. | Deposit date: | 2006-03-14 | Release date: | 2006-06-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Escherichia coli acid resistance: pH-sensing, activation by chloride and autoinhibition in GadB Embo J., 25, 2006
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1RNE
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1SBN
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1SIB
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2K7Z
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1HII
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2AXI
| HDM2 in complex with a beta-hairpin | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, SULFATE ION, Ubiquitin-protein ligase E3 Mdm2, ... | Authors: | Mittl, P.R.E, Fasan, R, Robinson, J, Gruetter, M.G. | Deposit date: | 2005-09-05 | Release date: | 2006-03-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure-Activity Studies in a Family of beta-Hairpin Protein Epitope Mimetic Inhibitors of the p53-HDM2 Protein-Protein Interaction. Chembiochem, 7, 2006
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4BS0
| Crystal Structure of Kemp Eliminase HG3.17 E47N,N300D Complexed with Transition State Analog 6-Nitrobenzotriazole | Descriptor: | 6-NITROBENZOTRIAZOLE, KEMP ELIMINASE HG3.17, SULFATE ION | Authors: | Blomberg, R, Kries, H, Pinkas, D.M, Mittl, P.R.E, Gruetter, M.G, Privett, H.K, Mayo, S, Hilvert, D. | Deposit date: | 2013-06-06 | Release date: | 2013-10-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Precision is Essential for Efficient Catalysis in an Evolved Kemp Eliminase Nature, 503, 2013
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4CDL
| Crystal Structure of Retro-aldolase RA110.4-6 Complexed with Inhibitor 1-(6-methoxy-2-naphthalenyl)-1,3-butanedione | Descriptor: | (2E)-1-(6-methoxynaphthalen-2-yl)but-2-en-1-one, STEROID DELTA-ISOMERASE | Authors: | Pinkas, D.M, Studer, S, Obexer, R, Giger, L, Gruetter, M.G, Baker, D, Hilvert, D. | Deposit date: | 2013-11-01 | Release date: | 2014-11-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Active Site Plasticity of a Computationally Designed Retro-Aldolase Enzyme To be Published
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4CG4
| Crystal structure of the CHS-B30.2 domains of TRIM20 | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, PYRIN, ... | Authors: | Weinert, C, Morger, D, Djekic, A, Mittl, P.R.E, Gruetter, M.G. | Deposit date: | 2013-11-20 | Release date: | 2015-04-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Trim20 C-Terminal Coiled-Coil/B30.2 Fragment: Implications for the Recognition of Higher Order Oligomers Sci.Rep., 5, 2015
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1AIE
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4LSZ
| Caspase-7 in Complex with DARPin D7.18 | Descriptor: | Caspase-7 subunit p10, Caspase-7 subunit p20, DARPin D7.18 | Authors: | Fluetsch, A, Lukarska, M, Gruetter, M.G. | Deposit date: | 2013-07-23 | Release date: | 2014-07-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise. Biochem.J., 461, 2014
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3EO1
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3EO0
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2FBE
| Crystal Structure of the PRYSPRY-domain | Descriptor: | PREDICTED: similar to ret finger protein-like 1 | Authors: | Gruetter, C, Briand, C, Capitani, G, Mittl, P.R, Gruetter, M.G. | Deposit date: | 2005-12-09 | Release date: | 2006-01-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Structure of the PRYSPRY-domain: Implications for autoinflammatory diseases Febs Lett., 580, 2006
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2MIB
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2P2C
| Inhibition of caspase-2 by a designed ankyrin repeat protein (DARPin) | Descriptor: | Caspase-2 | Authors: | Roschitzki Voser, H, Briand, C, Capitani, G, Gruetter, M.G. | Deposit date: | 2007-03-07 | Release date: | 2007-05-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism. Structure, 15, 2007
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4BPQ
| Structure and substrate induced conformational changes of the secondary citrate-sodium symporter CitS revealed by electron crystallography | Descriptor: | CITRATE:SODIUM SYMPORTER | Authors: | Kebbel, F, Kurz, M, Arheit, M, Gruetter, M.G, Stahlberg, H. | Deposit date: | 2013-05-27 | Release date: | 2013-07-17 | Last modified: | 2024-05-08 | Method: | ELECTRON CRYSTALLOGRAPHY (6 Å) | Cite: | Structure and Substrate-Induced Conformational Changes of the Secondary Citrate/Sodium Symporter Cits Revealed by Electron Crystallography. Structure, 21, 2013
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2I1B
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154L
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153L
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1C94
| REVERSING THE SEQUENCE OF THE GCN4 LEUCINE ZIPPER DOES NOT AFFECT ITS FOLD. | Descriptor: | RETRO-GCN4 LEUCINE ZIPPER | Authors: | Mittl, P.R.E, Deillon, C.A, Sargent, D, Liu, N, Klauser, S, Thomas, R.M, Gutte, B, Gruetter, M.G. | Deposit date: | 1999-07-30 | Release date: | 2000-03-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | The retro-GCN4 leucine zipper sequence forms a stable three-dimensional structure. Proc.Natl.Acad.Sci.USA, 97, 2000
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4Q4A
| Improved model of AMP-PNP bound TM287/288 | Descriptor: | ABC transporter, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Hohl, M, Gruetter, M.G, Seeger, M.A. | Deposit date: | 2014-04-14 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proc.Natl.Acad.Sci.USA, 111, 2014
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