1RNE

THE CRYSTAL STRUCTURE OF RECOMBINANT GLYCOSYLATED HUMAN RENIN ALONE AND IN COMPLEX WITH A TRANSITION STATE ANALOG INHIBITOR

Summary for 1RNE

• Entry DOI: 10.2210/pdb1rne/pdb
• Descriptor: RENIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, [[[3-(2-METHYL-PROPANE-2-SULFONYL)-1-BENZENYL]-2-PROPYL]-CARBONYL-HISTIDYL]-AMINO-[CYCLOHEXYLMETHYL]-[2-HYDROXY-4-ISOPROPYL]-PENTAN-5-OIC ACID BUTYLAMIDE, ... (4 entities in total)
• Functional Keywords: hydrolase(acid proteinase)
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 38218.23

Authors

Gruetter, M.G.,Rahuel, J.,Priestle, J.P. (deposition date: 1991-12-12, release date: 1993-10-31, Last modification date: 2020-10-21)

• Primary citation: Rahuel, J.,Priestle, J.P.,Grutter, M.G.; The crystal structures of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor.; J.Struct.Biol., 107:227-236, 1991; PubMed: 1807356; DOI: 10.1016/1047-8477(91)90048-2

Experimental method

X-RAY DIFFRACTION (2.4 Å)