2AR9
Crystal structure of a dimeric caspase-9
Summary for 2AR9
Entry DOI | 10.2210/pdb2ar9/pdb |
Descriptor | Caspase-9, D-MALATE (3 entities in total) |
Functional Keywords | caspase, caspase activation, initiator caspase, cysteine protease, engineered caspase-9, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 122349.34 |
Authors | Chao, Y.,Shiozaki, E.N.,Srinivassula, S.M.,Rigotti, D.J.,Fairman, R.,Shi, Y. (deposition date: 2005-08-19, release date: 2005-10-11, Last modification date: 2023-08-23) |
Primary citation | Chao, Y.,Shiozaki, E.N.,Srinivassula, S.M.,Rigotti, D.J.,Fairman, R.,Shi, Y. Engineering a Dimeric Caspase-9: A Re-Evaluation of the Induced Proximity Model for Caspase Activation PLOS BIOL., 3:1079-1087, 2005 Cited by PubMed: 15941357DOI: 10.1371/journal.pbio.0030183 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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