5BKM
| Crystal Structure of Hip1 (Rv2224c) mutant - S228DHA (dehydroalanine) | 分子名称: | Carboxylesterase A | 著者 | Naffin-Olivos, J.L, Daab, A, Goldfarb, N.E, Doran, M.H, Baikovitz, J, Liu, D, Sun, S, White, A, Dunn, B.M, Rengarajan, J, Petsko, G.A, Ringe, D. | 登録日 | 2021-03-20 | 公開日 | 2022-03-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Crystal Structure of Hip1 (Rv2224c) mutant - S228DHA (dehydroalanine) To Be Published
|
|
5C8X
| ZHD-Intermediate complex after ZHD crystal soaking in ZEN for 20min | 分子名称: | (1E,10S)-1-(3,5-dihydroxyphenyl)-10-hydroxyundec-1-en-6-one, GLYCEROL, POTASSIUM ION, ... | 著者 | Hu, X.-J, Qi, Q, Yang, W.-J. | 登録日 | 2015-06-26 | 公開日 | 2016-06-29 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A Case Study of Lactonase ZHD To Be Published
|
|
5C8Z
| ZHD-ZGR complex after ZHD crystal soaking in ZEN for 30min | 分子名称: | 2,4-dihydroxy-6-[(1E,10S)-10-hydroxy-6-oxoundec-1-en-1-yl]benzoic acid, FORMIC ACID, GLYCEROL, ... | 著者 | Hu, X.-J, Qi, Q, Yang, W.-J. | 登録日 | 2015-06-26 | 公開日 | 2016-06-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The structure of a complex of the lactonohydrolase zearalenone hydrolase with the hydrolysis product of zearalenone at 1.60 angstrom resolution. Acta Crystallogr F Struct Biol Commun, 73, 2017
|
|
5C7Y
| ZHD-Intermediate complex after ZHD crystal soaking in ZEN for 9min | 分子名称: | (1E,10S)-1-(3,5-dihydroxyphenyl)-10-hydroxyundec-1-en-6-one, FORMIC ACID, GLYCEROL, ... | 著者 | Hu, X.-J, Qi, Q, Yang, W.-J. | 登録日 | 2015-06-25 | 公開日 | 2016-06-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A Case Study of Lactonase ZHD To Be Published
|
|
5C81
| ZHD-Intermediate complex after ZHD crystal soaking in ZEN for 12min | 分子名称: | (1E,10S)-1-(3,5-dihydroxyphenyl)-10-hydroxyundec-1-en-6-one, FORMIC ACID, GLYCEROL, ... | 著者 | Hu, X.-J, Qi, Q, Yang, W.-J. | 登録日 | 2015-06-25 | 公開日 | 2016-06-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A Case Study of Lactonase ZHD To Be Published
|
|
5CW2
| |
5D7B
| Trigonal Crystal Structure of an acetylester hydrolase from Corynebacterium glutamicum | 分子名称: | GLYCEROL, Homoserine O-acetyltransferase | 著者 | Niefind, K, Toelzer, C, Pal, S, Altenbuchner, J, Watzlawick, H. | 登録日 | 2015-08-13 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | A novel esterase subfamily with alpha / beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases. Febs Lett., 590, 2016
|
|
5D6O
| Orthorhombic Crystal Structure of an acetylester hydrolase from Corynebacterium glutamicum | 分子名称: | CHLORIDE ION, GLYCEROL, Homoserine O-acetyltransferase, ... | 著者 | Niefind, K, Toelzer, C, Altenbuchner, J, Watzlawick, H. | 登録日 | 2015-08-12 | 公開日 | 2015-12-09 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A novel esterase subfamily with alpha / beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases. Febs Lett., 590, 2016
|
|
5E4Y
| Orthorhombic structure of the acetyl esterase MekB | 分子名称: | Homoserine O-acetyltransferase | 著者 | Niefind, K, Toelzer, C, Pal, S, Watzlawick, H, Altenbuchner, J. | 登録日 | 2015-10-07 | 公開日 | 2015-12-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A novel esterase subfamily with alpha / beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to l-homoserine O-acetyl transferases. Febs Lett., 590, 2016
|
|
5EGN
| |
3KOO
| Crystal Structure of soluble epoxide Hydrolase | 分子名称: | Epoxide hydrolase 2, N-(2,4-dichlorobenzyl)-4-(pyrimidin-2-yloxy)piperidine-1-carboxamide | 著者 | Farrow, N.A. | 登録日 | 2009-11-13 | 公開日 | 2010-04-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.791 Å) | 主引用文献 | Optimization of piperidyl-ureas as inhibitors of soluble epoxide hydrolase. Bioorg.Med.Chem.Lett., 20, 2010
|
|
8G5T
| |
8G5U
| Crystal structure of TnmK2 complexed with TNM B | 分子名称: | TnmK2, methyl (2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate | 著者 | Liu, Y.-C, Gui, C, Shen, B. | 登録日 | 2023-02-14 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.804 Å) | 主引用文献 | Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis. Nat.Chem.Biol., 20, 2024
|
|
5FP0
| ligand complex structure of soluble epoxide hydrolase | 分子名称: | BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, N-cyclopentyl-2-[4-(trifluoromethyl)phenyl]-3H-benzimidazole-4-sulfonamide | 著者 | Xue, Y, Olsson, T, Johansson, C.A, Oster, L, Beisel, H.G, Rohman, M, Karis, D, Backstrom, S. | 登録日 | 2015-11-26 | 公開日 | 2016-03-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Fragment Screening of Soluble Epoxide Hydrolase for Lead Generation-Structure-Based Hit Evaluation and Chemistry Exploration. Chemmedchem, 11, 2016
|
|
1EK1
| CRYSTAL STRUCTURE OF MURINE SOLUBLE EPOXIDE HYDROLASE COMPLEXED WITH CIU INHIBITOR | 分子名称: | EPOXIDE HYDROLASE, N-CYCLOHEXYL-N'-(4-IODOPHENYL)UREA | 著者 | Argiriadi, M.A, Morisseau, C, Goodrow, M.H, Dowdy, D.L, Hammock, B.D, Christianson, D.W. | 登録日 | 2000-03-06 | 公開日 | 2000-05-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation. J.Biol.Chem., 275, 2000
|
|
6YNX
| Cryo-EM structure of Tetrahymena thermophila mitochondrial ATP synthase - Fo-subcomplex | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Kock Flygaard, R, Muhleip, A, Amunts, A. | 登録日 | 2020-04-14 | 公開日 | 2020-09-30 | 最終更新日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization. Nat Commun, 11, 2020
|
|
4OCZ
| Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea | 分子名称: | 1-[1-(2-methylpropanoyl)piperidin-4-yl]-3-[4-(trifluoromethyl)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | 著者 | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morriseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | 登録日 | 2014-01-09 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J.Med.Chem., 57, 2014
|
|
4OD0
| Crystal structure of human soluble epoxide hydrolase complexed with 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea | 分子名称: | 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | 著者 | Lee, K.S.S, Liu, J, Wagner, K.M, Pakhomova, S, Dong, H, Morisseau, C, Fu, S.H, Yang, J, Wang, P, Ulu, A, Mate, C, Nguyen, L, Wullf, H, Eldin, M.L, Mara, A.A, Newcomer, M.E, Zeldin, D.C, Hammock, B.D. | 登録日 | 2014-01-09 | 公開日 | 2014-09-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J.Med.Chem., 57, 2014
|
|
4QF0
| |
4QES
| |
4QFF
| |
2ES4
| Crystal structure of the Burkholderia glumae lipase-specific foldase in complex with its cognate lipase | 分子名称: | CALCIUM ION, IODIDE ION, Lipase, ... | 著者 | Pauwels, K, Wyns, L, Tommassen, J, Savvides, S.N, Van Gelder, P. | 登録日 | 2005-10-25 | 公開日 | 2006-03-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of a membrane-based steric chaperone in complex with its lipase substrate. Nat.Struct.Mol.Biol., 13, 2006
|
|
8QVI
| Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. | 分子名称: | Bifunctional epoxide hydrolase 2, DI(HYDROXYETHYL)ETHER | 著者 | Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. | 登録日 | 2023-10-18 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Exploring serial crystallography for drug discovery To Be Published
|
|
8B6T
| X-ray structure of the interface optimized haloalkane dehalogenase HaloTag7 fusion to the green fluorescent protein GFP (ChemoG5-TMR) labeled with a chloroalkane tetramethylrhodamine fluorophore substrate | 分子名称: | CHLORIDE ION, Green fluorescent protein,Haloalkane dehalogenase, [9-[2-carboxy-5-[2-[2-(6-chloranylhexoxy)ethoxy]ethylcarbamoyl]phenyl]-6-(dimethylamino)xanthen-3-ylidene]-dimethyl-azanium | 著者 | Tarnawski, M, Hellweg, L, Hiblot, J. | 登録日 | 2022-09-27 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A general method for the development of multicolor biosensors with large dynamic ranges. Nat.Chem.Biol., 19, 2023
|
|
8B6S
| X-ray structure of the haloalkane dehalogenase HaloTag7 fusion to the green fluorescent protein GFP (ChemoG1) labeled with a chloroalkane tetramethylrhodamine fluorophore substrate | 分子名称: | CHLORIDE ION, GLYCEROL, Green fluorescent protein,Haloalkane dehalogenase, ... | 著者 | Tarnawski, M, Hellweg, L, Hiblot, J. | 登録日 | 2022-09-27 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A general method for the development of multicolor biosensors with large dynamic ranges. Nat.Chem.Biol., 19, 2023
|
|