6X5Z
 
 | | Bovine Cardiac Myosin in Complex with Chicken Skeletal Actin and Human Cardiac Tropomyosin in the Rigor State | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J, Bullitt, E. | | Deposit date: | 2020-05-27 | | Release date: | 2020-07-22 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.24 Å) | | Cite: | Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments.
Biophys.J., 119, 2020
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8EFI
 | | Helical reconstruction of the human cardiac actin-tropomyosin-myosin complex in the rigor form | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | | Deposit date: | 2022-09-08 | | Release date: | 2022-11-23 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation.
J.Gen.Physiol., 155, 2023
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8ENC
 | | Helical reconstruction of the human cardiac actin-tropomyosin-myosin loop 4 7G mutant complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | | Deposit date: | 2022-09-29 | | Release date: | 2022-11-23 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation.
J.Gen.Physiol., 155, 2023
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8EFE
 | | Human beta-cardiac myosin II bound to ADP-MG2+ and the associated essential light chain | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Beta-cardiac myosin II, MAGNESIUM ION, ... | | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | | Deposit date: | 2022-09-08 | | Release date: | 2023-01-11 | | Last modified: | 2023-01-25 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin.
J.Gen.Physiol., 155, 2023
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8EFD
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8EFH
 | | Helical reconstruction of the human cardiac actin-tropomyosin-myosin complex in complex with ADP-Mg2+ | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | | Deposit date: | 2022-09-08 | | Release date: | 2023-01-11 | | Last modified: | 2023-01-25 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin.
J.Gen.Physiol., 155, 2023
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8EHS
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8EHR
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8EHT
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7M7C
 | | Crystal Structure of Hip1 (Rv2224c) mutant - T466A/S228DHA (dehydroalanine) | | Descriptor: | Carboxylesterase A | | Authors: | Naffin-Olivos, J.L, Daab, A, Goldfarb, N.E, Doran, M.H, Baikovitz, J, Liu, D, Sun, S, White, A, Dunn, B.M, Rengarajan, J, Petsko, G.A, Ringe, D. | | Deposit date: | 2021-03-27 | | Release date: | 2022-03-30 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Inhibitors and Inactivators of Mycobacterium tuberculosis serine protease Hip1 (Rv2224c)
To Be Published
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5BKM
 | | Crystal Structure of Hip1 (Rv2224c) mutant - S228DHA (dehydroalanine) | | Descriptor: | Carboxylesterase A | | Authors: | Naffin-Olivos, J.L, Daab, A, Goldfarb, N.E, Doran, M.H, Baikovitz, J, Liu, D, Sun, S, White, A, Dunn, B.M, Rengarajan, J, Petsko, G.A, Ringe, D. | | Deposit date: | 2021-03-20 | | Release date: | 2022-03-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Crystal Structure of Hip1 (Rv2224c) mutant - S228DHA (dehydroalanine)
To Be Published
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