6QX9
| Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Charenton, C, Wilkinson, M.E, Nagai, K. | 登録日 | 2019-03-07 | 公開日 | 2019-04-17 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Mechanism of 5' splice site transfer for human spliceosome activation. Science, 364, 2019
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2AYO
| Structure of USP14 bound to ubquitin aldehyde | 分子名称: | Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 14 | 著者 | Hu, M, Li, P, Jeffrey, P.D, Shi, Y. | 登録日 | 2005-09-07 | 公開日 | 2005-10-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14. Embo J., 24, 2005
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2Y5B
| Structure of USP21 in complex with linear diubiquitin-aldehyde | 分子名称: | SULFATE ION, UBIQUITIN, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 21, ... | 著者 | Ye, Y, Akutsu, M, Reyes-Turcu, F, Enchev, R.I, Wilkinson, K.D, Komander, D. | 登録日 | 2011-01-12 | 公開日 | 2012-01-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Polyubiquitin Binding and Cross-Reactivity in the Usp Domain Deubiquitinase Usp21. Embo Rep., 12, 2011
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8WG5
| Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | 著者 | Ai, H.S, He, Z.Z, Deng, Z.H, Liu, L. | 登録日 | 2023-09-20 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome To Be Published
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5GJQ
| Structure of the human 26S proteasome bound to USP14-UbAl | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | 著者 | Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G. | 登録日 | 2016-07-01 | 公開日 | 2016-08-17 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | An atomic structure of the human 26S proteasome. Nat. Struct. Mol. Biol., 23, 2016
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8Y6O
| Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R. | 登録日 | 2024-02-02 | 公開日 | 2024-03-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome. Science, 383, 2024
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7AY1
| Cryo-EM structure of USP1-UAF1 bound to mono-ubiquitinated FANCD2, and FANCI | 分子名称: | DNA (61-MER), Fanconi anemia group D2 protein, Fanconi anemia group I protein, ... | 著者 | Rennie, M.L, Arkinson, C, Walden, H. | 登録日 | 2020-11-10 | 公開日 | 2021-03-24 | 最終更新日 | 2022-07-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of FANCD2 deubiquitination by USP1-UAF1. Nat.Struct.Mol.Biol., 28, 2021
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7AY0
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7AY2
| Crystal structure of truncated USP1-UAF1 reacted with ubiquitin-prg | 分子名称: | Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 1, WD repeat-containing protein 48, ... | 著者 | Arkinson, C, Rennie, M.L, Walden, H. | 登録日 | 2020-11-10 | 公開日 | 2021-03-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis of FANCD2 deubiquitination by USP1-UAF1. Nat.Struct.Mol.Biol., 28, 2021
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6ML1
| Structure of the USP15 deubiquitinase domain in complex with an affinity-matured inhibitory Ubv | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. | 登録日 | 2018-09-26 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
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3I3T
| Crystal structure of covalent ubiquitin-USP21 complex | 分子名称: | ETHANAMINE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 21, ... | 著者 | Neculai, D, Avvakumov, G.V, Walker, J.R, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2009-06-30 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
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3IHP
| Covalent Ubiquitin-Usp5 Complex | 分子名称: | CHLORIDE ION, ETHANAMINE, Ubiquitin, ... | 著者 | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2009-07-30 | 公開日 | 2009-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Covalent Ubiquitin-Usp5 Complex To be Published
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3JCR
| 3D structure determination of the human*U4/U6.U5* tri-snRNP complex | 分子名称: | LSm2, LSm3, LSm4, ... | 著者 | Agafonov, D.E, Kastner, B, Dybkov, O, Hofele, R.V, Liu, W.T, Urlaub, H, Luhrmann, R, Stark, H. | 登録日 | 2016-01-21 | 公開日 | 2016-03-09 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Molecular architecture of the human U4/U6.U5 tri-snRNP. Science, 351, 2016
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3V6E
| Crystal Structure of USP2 and a mutant form of Ubiquitin | 分子名称: | CHLORIDE ION, GLYCEROL, Ubiquitin, ... | 著者 | Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2011-12-19 | 公開日 | 2012-12-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
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7QO6
| 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the s2 state | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | 著者 | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | 登録日 | 2021-12-23 | 公開日 | 2022-03-16 | 最終更新日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | 主引用文献 | Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13, 2022
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7QO5
| 26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | 著者 | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | 登録日 | 2021-12-23 | 公開日 | 2022-03-16 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13, 2022
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7QO4
| 26S proteasome WT-Ubp6-UbVS complex in the si state (ATPases, Rpn1, Ubp6, and UbVS) | 分子名称: | 26S proteasome regulatory subunit RPN1, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, C, Joshi, T, Rudack, T, Sakata, E, Finley, D. | 登録日 | 2021-12-23 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13, 2022
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6DGF
| Ubiquitin Variant bound to USP2 | 分子名称: | Polyubiquitin-B, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 2, ... | 著者 | Manczyk, N, Sicheri, F. | 登録日 | 2018-05-17 | 公開日 | 2019-02-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases. J. Mol. Biol., 431, 2019
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3WXG
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3WXE
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3WXF
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2HD5
| USP2 in complex with ubiquitin | 分子名称: | Polyubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ZINC ION | 著者 | Renatus, M, Kroemer, M. | 登録日 | 2006-06-20 | 公開日 | 2006-08-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Basis of Ubiquitin Recognition by the Deubiquitinating Protease USP2. Structure, 14, 2006
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2IBI
| Covalent Ubiquitin-USP2 Complex | 分子名称: | ETHANAMINE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ... | 著者 | Walker, J.R, Avvakumov, G.V, Bernstein, G, Xue, S, Finerty Jr, P.J, MacKenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-09-11 | 公開日 | 2006-10-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Covalent Ubiquitin-USP2 Complex To be Published
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8H6J
| Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, W, Zhan, X, Zhang, X, Lei, J, Yan, C, Shi, Y. | 登録日 | 2022-10-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 2024
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8H6E
| Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, W, Zhan, X, Zhang, X, Bai, R, Lei, J, Yan, C, Shi, Y. | 登録日 | 2022-10-17 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into human exon-defined spliceosome prior to activation. Cell Res., 2024
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