PDB: 258 件ウェブページステータス検索Chemie searchBIRD

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3HK0	Crystal Structure of the RA and PH Domains of Grb10 分子名称: Growth factor receptor-bound protein 10, THIOCYANATE ION 著者 Hubbard, S.R, Depetris, R.S, Wu, J. 登録日 2009-05-22 公開日 2009-08-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14. Nat.Struct.Mol.Biol., 16, 2009
3HW2	Crystal structure of the SifA-SKIP(PH) complex 分子名称: Pleckstrin homology domain-containing family M member 2, Protein sifA 著者 Diacovich, L, Dumont, A, Lafitte, D, Soprano, E, Guilhon, A.-A, Bignon, C, Gorvel, J.-P, Bourne, Y, Meresse, S. 登録日 2009-06-17 公開日 2009-11-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Interaction between the SifA virulence factor and its host target skip is essential for salmonella pathogenesis J.Biol.Chem., 284, 2009
6TT2	The PH domain of Bruton's tyrosine kinase mutant R28C 分子名称: MAGNESIUM ION, Tyrosine-protein kinase BTK, ZINC ION 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2019-12-23 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
6TSE	Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C 分子名称: 1-methylindole-2,3-dione, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2019-12-20 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
6TUH	The PH domain of Bruton's tyrosine kinase mutant R28C 分子名称: 4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
6U3E	Best fitting antiparallel model for Volume 1 of truncated dimeric Cytohesin-3 (Grp1; amino acids 14-399) 分子名称: Cytohesin-3, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE 著者 Das, S, Lambright, D.G. 登録日 2019-08-21 公開日 2019-09-25 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (53 Å) 主引用文献 Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes. Structure, 27, 2019
6TVN	Crystal Structure of 5-bromoindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase 分子名称: 5-bromanyl-1,3-dihydroindol-2-one, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2020-01-10 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
6U3G	Best fitting antiparallel model for Volume 2 of truncated dimeric Cytohesin-3 (Grp1; amino acids 14-399) 分子名称: Cytohesin-3, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE 著者 Das, S, Lambright, D.G. 登録日 2019-08-21 公開日 2019-09-25 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (53 Å) 主引用文献 Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes. Structure, 27, 2019
4CKH	Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy 分子名称: ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 著者 Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F. 登録日 2014-01-06 公開日 2014-10-15 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (17 Å) 主引用文献 A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature. Dev.Cell, 31, 2014
4CKG	Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy 分子名称: ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 著者 Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F. 登録日 2014-01-06 公開日 2014-10-15 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature. Dev.Cell, 31, 2014
8S93	Crystal structure of the PH-TH/kinase complex of Bruton's tyrosine kinase 分子名称: 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, GLYCEROL, Tyrosine-protein kinase BTK, ... 著者 Lin, D.Y, Andreotti, A.H. 登録日 2023-03-27 公開日 2023-08-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Elife, 12, 2024
8SZ8	Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state (full helix) 分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-05-27 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
8T0K	Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state 分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-06-01 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
8SXZ	Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state 分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-05-24 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
8SZ7	Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state showing the second PH domain 分子名称: Dynamin-1 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-05-27 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.84 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
8SZ4	Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state showing the PH domain 分子名称: Dynamin-1 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-05-26 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
8T0R	Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state (full helix) 分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-06-01 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.97 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
3KSY	Crystal structure of the Histone domain, DH-PH unit, and catalytic unit of the Ras activator Son of Sevenless (SOS) 分子名称: Son of sevenless homolog 1 著者 Gureasko, J, Kuchment, O, Kuriyan, J. 登録日 2009-11-24 公開日 2010-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.178 Å) 主引用文献 Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless. Proc.Natl.Acad.Sci.USA, 107, 2010
3LJU	Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3 分子名称: (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, Arf-GAP with dual PH domain-containing protein 1, ZINC ION 著者 Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2010-01-26 公開日 2010-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.702 Å) 主引用文献 Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1. Proc.Natl.Acad.Sci.USA, 107, 2010
3MDB	Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4 分子名称: (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, Arf-GAP with dual PH domain-containing protein 1, Kinesin-like protein KIF13B, ... 著者 Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2010-03-30 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.952 Å) 主引用文献 Crystal structure of the ternary complex of full length centaurin alpha-1, KIF13B FHA domain, and IP4 to be published
4F7H	The crystal structure of kindlin-2 pleckstrin homology domain in free form 分子名称: Fermitin family homolog 2, S,R MESO-TARTARIC ACID 著者 Liu, Y, Zhu, Y, Qin, J, Ye, S, Zhang, R. 登録日 2012-05-16 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation. Protein Cell, 3, 2012
3MPX	Crystal structure of the DH and PH-1 domains of human FGD5 分子名称: FYVE, RhoGEF and PH domain-containing protein 5, UNKNOWN ATOM OR ION 著者 Shen, Y, Nedyalkova, L, Tong, Y, Tempel, W, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2010-04-27 公開日 2010-06-23 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the DH and PH-1 domains of human FGD5 TO BE PUBLISHED
4GMV	Crystal Structure of the coiled-coil, RA and PH domains of Lamellipodin 分子名称: Ras-associated and pleckstrin homology domains-containing protein 1 著者 Chang, Y.C.E, Wu, J. 登録日 2012-08-16 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling. Protein Cell, 4, 2013
4GN1	Crystal Structure of the RA and PH domains of Lamellipodin 分子名称: MALONATE ION, Ras-associated and pleckstrin homology domains-containing protein 1 著者 Chang, Y.C.E, Wu, J. 登録日 2012-08-16 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling. Protein Cell, 4, 2013
4GZU	Crystal structure of the DH-PH-PH domain of FARP2 分子名称: FERM, RhoGEF and pleckstrin domain-containing protein 2 著者 He, X, Zhang, X. 登録日 2012-09-06 公開日 2013-03-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Basis for Autoinhibition of the Guanine Nucleotide Exchange Factor FARP2. Structure, 21, 2013

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