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4F7H

The crystal structure of kindlin-2 pleckstrin homology domain in free form

Summary for 4F7H
Entry DOI10.2210/pdb4f7h/pdb
Related2LKO
DescriptorFermitin family homolog 2, S,R MESO-TARTARIC ACID (3 entities in total)
Functional Keywordsbeta-barrel, membrane binding, integrin activation, cytoplasmic membrane, cell adhesion
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cell cortex: Q96AC1
Total number of polymer chains1
Total formula weight19733.31
Authors
Liu, Y.,Zhu, Y.,Qin, J.,Ye, S.,Zhang, R. (deposition date: 2012-05-16, release date: 2012-06-13, Last modification date: 2023-09-13)
Primary citationLiu, Y.,Zhu, Y.,Ye, S.,Zhang, R.
Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation.
Protein Cell, 3:434-440, 2012
Cited by
PubMed: 22653426
DOI: 10.1007/s13238-012-2046-1
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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