1ZFP
| |
1Z3K
| |
2AOA
| Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain | 分子名称: | 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Growth factor receptor-bound protein 2 | 著者 | Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. | 登録日 | 2005-08-12 | 公開日 | 2005-10-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
|
|
2AUG
| Crystal structure of the Grb14 SH2 domain | 分子名称: | Growth factor receptor-bound protein 14 | 著者 | Depetris, R.S, Hu, J, Gimpelevich, I, Holt, L.J, Daly, R.J, Hubbard, S.R. | 登録日 | 2005-08-27 | 公開日 | 2005-11-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for inhibition of the insulin receptor by the adaptor protein grb14. Mol.Cell, 20, 2005
|
|
2AOB
| Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain | 分子名称: | 2-(4-((9S,10S,14S,Z)-18-(2-AMINO-2-OXOETHYL)-9-(CARBOXYMETHYL)-14-(NAPHTHALEN-1-YLMETHYL)-8,17,20-TRIOXO-7,16,19-TRIAZASPIRO[5.14]ICOS-11-EN-10-YL)PHENYL)MALONIC ACID, Growth factor receptor-bound protein 2 | 著者 | Phan, J, Shi, Z.D, Burke, T.R, Waugh, D.S. | 登録日 | 2005-08-12 | 公開日 | 2005-10-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structures of a High-affinity Macrocyclic Peptide Mimetic in Complex with the Grb2 SH2 Domain. J.Mol.Biol., 353, 2005
|
|
2BBU
| |
8X2P
| The Crystal Structure of LCK from Biortus. | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, TETRAETHYLENE GLYCOL, ... | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Lu, Y. | 登録日 | 2023-11-10 | 公開日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The Crystal Structure of LCK from Biortus. To Be Published
|
|
2JYQ
| NMR structure of the apo v-Src SH2 domain | 分子名称: | Tyrosine-protein kinase transforming protein Src | 著者 | Taylor, J.D, Ababou, A, Williams, M.A, Ladbury, J.E. | 登録日 | 2007-12-17 | 公開日 | 2008-06-24 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, dynamics, and binding thermodynamics of the v-Src SH2 domain: Implications for drug design Proteins, 73, 2008
|
|
2KK6
| Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d | 分子名称: | Proto-oncogene tyrosine-protein kinase FER | 著者 | Tang, Y, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-15 | 公開日 | 2009-08-11 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d To be Published
|
|
2KNO
| |
2L3T
| |
2L4K
| Water refined solution structure of the human Grb7-SH2 domain in complex with the 10 amino acid peptide pY1139 | 分子名称: | Growth factor receptor-bound protein 7, Receptor tyrosine-protein kinase erbB-2 | 著者 | Pias, S.C, Ivancic, M, Brescia, P.J, Johnson, D.L, Smith, D.E, Daly, R.J, Lyons, B.A. | 登録日 | 2010-10-07 | 公開日 | 2010-11-17 | 最終更新日 | 2012-10-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Water-Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139. Protein Pept.Lett., 19, 2012
|
|
2L6K
| Solution Structure of a Nonphosphorylated Peptide Recognizing Domain | 分子名称: | Tensin-like C1 domain-containing phosphatase | 著者 | Dai, K, Liao, S, Zhang, J, Zhang, X, Tu, X. | 登録日 | 2010-11-22 | 公開日 | 2011-10-12 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Tensin2 SH2 domain and its phosphotyrosine-independent interaction with DLC-1 Plos One, 6, 2011
|
|
2LNW
| Identification and structural basis for a novel interaction between Vav2 and Arap3 | 分子名称: | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, Guanine nucleotide exchange factor VAV2 | 著者 | Wu, B, Zhang, J, Wu, J, Shi, Y. | 登録日 | 2012-01-05 | 公開日 | 2012-11-21 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Identification and structural basis for a novel interaction between Vav2 and Arap3. J.Struct.Biol., 180, 2012
|
|
2LNX
| |
2LCT
| |
2MC1
| Solution structure of the Vav1 SH2 domain complexed with a Syk-derived singly phosphorylated peptide | 分子名称: | Proto-oncogene vav, Tyrosine-protein kinase SYK | 著者 | Chen, C, Piraner, D, Gorenstein, N.M, Geahlen, R.L, Post, C.B. | 登録日 | 2013-08-13 | 公開日 | 2013-08-28 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain. Biopolymers, 99, 2013
|
|
2MK2
| Solution NMR structure of N-terminal domain (SH2 domain) of human Inositol polyphosphate phosphatase-like protein 1 (INPPL1) (fragment 20-117), Northeast Structural Genomics Consortium Target HR9134A | 分子名称: | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | 著者 | Yang, Y, Ramelot, T.A, Janjua, H, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2014-01-23 | 公開日 | 2014-03-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of N-terminal domain (SH2 domain) of human Inositol polyphosphate phosphatase-like protein 1 (INPPL1) (fragment 20-117), Northeast Structural Genomics Consortium Target HR9134A. To be Published
|
|
2MQI
| |
2MRJ
| |
2MRK
| Fyn SH2 domain in complex with the natural inhibitory phosphotyrosine peptide | 分子名称: | C-terminal Tyrosine-protein kinase Fyn, Tyrosine-protein kinase Fyn | 著者 | Huculeci, R, Buts, L, Lenaerts, A.J, van Nuland, N. | 登録日 | 2014-07-09 | 公開日 | 2015-07-15 | 最終更新日 | 2016-12-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Dynamically Coupled Residues within the SH2 Domain of FYN Are Key to Unlocking Its Activity. Structure, 24, 2016
|
|
2PNB
| STRUCTURE OF AN SH2 DOMAIN OF THE P85 ALPHA SUBUNIT OF PHOSPHATIDYLINOSITOL-3-OH KINASE | 分子名称: | PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT N-TERMINAL SH2 DOMAIN | 著者 | Booker, G.W, Breeze, A.L, Downing, A.K, Panayotou, G, Gout, I, Waterfield, M.D, Campbell, I.D. | 登録日 | 1992-06-30 | 公開日 | 1994-01-31 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase. Nature, 358, 1992
|
|
2PLE
| NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE | 分子名称: | PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF | 著者 | Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. | 登録日 | 1994-08-19 | 公開日 | 1995-01-26 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
|
|
2PLD
| NUCLEAR MAGNETIC RESONANCE STRUCTURE OF AN SH2 DOMAIN OF PHOSPHOLIPASE C-GAMMA1 COMPLEXED WITH A HIGH AFFINITY BINDING PEPTIDE | 分子名称: | PHOSPHOLIPASE C GAMMA-1, C-TERMINAL SH2 DOMAIN, PHOSPHOPEPTIDE FROM PDGF | 著者 | Pascal, S.M, Singer, A.U, Gish, G, Yamazaki, T, Shoelson, S.E, Pawson, T, Kay, L.E, Forman-Kay, J.D. | 登録日 | 1994-08-19 | 公開日 | 1995-01-26 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell(Cambridge,Mass.), 77, 1994
|
|
1F1W
| SRC SH2 THREF1TRP MUTANT COMPLEXED WITH THE PHOSPHOPEPTIDE S(PTR)VNVQN | 分子名称: | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, S(PTR)VNVQN PHOSPHOPEPTIDE | 著者 | Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F. | 登録日 | 2000-05-20 | 公開日 | 2000-07-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for specificity switching of the Src SH2 domain. Mol.Cell, 5, 2000
|
|