1F1W

SRC SH2 THREF1TRP MUTANT COMPLEXED WITH THE PHOSPHOPEPTIDE S(PTR)VNVQN

Summary for 1F1W

• Entry DOI: 10.2210/pdb1f1w/pdb
• Related: 1F2F
• Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, S(PTR)VNVQN PHOSPHOPEPTIDE (3 entities in total)
• Functional Keywords: src, sh2 domain, phosphopeptide, specificity switch, transferase
• Biological source: Gallus gallus (chicken); More
• Cellular location: Cell membrane (By similarity): P00523
• Total number of polymer chains: 2
• Total formula weight: 12961.50

Authors

Kimber, M.S.,Nachman, J.,Cunningham, A.M.,Gish, G.D.,Pawson, T.,Pai, E.F. (deposition date: 2000-05-20, release date: 2000-07-06, Last modification date: 2023-11-15)

• Primary citation: Kimber, M.S.,Nachman, J.,Cunningham, A.M.,Gish, G.D.,Pawson, T.,Pai, E.F.; Structural basis for specificity switching of the Src SH2 domain.; Mol.Cell, 5:1043-1049, 2000; PubMed: 10911998; DOI: 10.1016/S1097-2765(00)80269-5

Experimental method

X-RAY DIFFRACTION (2.1 Å)