PDB: 302 resultsInfo pagesStatus searchChemie searchBIRD

---

3KD1	Closed binary complex of an RB69 gp43 fingers domain mutant complexed with an acyclic GMP terminated primer template pair. Descriptor: DNA (5'-D(*CP*GP*TP*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(4DG))-3'), DNA polymerase, ... Authors: Zahn, K.E, Doublie, S. Deposit date: 2009-10-22 Release date: 2011-04-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.66 Å) Cite: Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase. J.Biol.Chem., 286, 2011
7S0T	Structure of DNA polymerase zeta with mismatched DNA Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... Authors: Malik, R, Ubarretxena, I.B, Aggarwal, A.K. Deposit date: 2021-08-31 Release date: 2022-03-09 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Cryo-EM structure of translesion DNA synthesis polymerase zeta with a base pair mismatch. Nat Commun, 13, 2022
6AS7	CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF HUMAN DNA POLYMERASE ALPHA IN TERNARY COMPLEX WITH AN DNA-PRIMED DNA TEMPLATE AND DCTP Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, COBALT (II) ION, DNA (5'-D(*AP*GP*GP*CP*GP*CP*TP*CP*CP*AP*GP*GP*C)-3'), ... Authors: Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. Deposit date: 2017-08-23 Release date: 2018-03-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Activity and fidelity of human DNA polymerase alpha depend on primer structure. J. Biol. Chem., 293, 2018
7Z13	S. cerevisiae CMGE dimer nucleating origin DNA melting Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, ... Authors: Lewis, J.S, Sousa, J.S, Costa, A. Deposit date: 2022-02-24 Release date: 2022-06-15 Last modified: 2022-07-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Mechanism of replication origin melting nucleated by CMG helicase assembly. Nature, 606, 2022
5OMV	Ternary complex of 9N DNA polymerase in the replicative state with two metal ions in the active site Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, DNA primer, ... Authors: Betz, K, Marx, A, Diederichs, K. Deposit date: 2017-08-01 Release date: 2017-12-20 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.003 Å) Cite: Crystal structures of ternary complexes of archaeal B-family DNA polymerases. PLoS ONE, 12, 2017
7F4Y	Crystal structure of replisomal dimer of DNA polymerase from bacteriophage RB69 with DNA duplexes Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*AP*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*C)-3'), ... Authors: Youn, H.-S, Park, J, An, J.Y, Lee, Y, Eom, S.H, Wang, J. Deposit date: 2021-06-21 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of New Binary and Ternary DNA Polymerase Complexes From Bacteriophage RB69. Front Mol Biosci, 8, 2021
7KC0	Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ... Authors: Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E. Deposit date: 2020-10-04 Release date: 2020-12-02 Last modified: 2020-12-16 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA. Proc.Natl.Acad.Sci.USA, 117, 2020
5EXR	Crystal structure of human primosome Descriptor: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... Authors: Tahirov, T.H, Baranovskiy, A.G, Babayeva, N.D. Deposit date: 2015-11-24 Release date: 2016-03-23 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome. J.Biol.Chem., 291, 2016
1IH7	High-Resolution Structure of Apo RB69 DNA Polymerase Descriptor: DNA POLYMERASE, GUANOSINE, POTASSIUM ION Authors: Franklin, M.C, Wang, J, Steitz, T.A. Deposit date: 2001-04-18 Release date: 2001-06-13 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Structure of the Replicating Complex of a Pol alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
5H12	Crystal structure of Deep Vent DNA Polymerase Descriptor: Deep Vent DNA Polymerase Authors: Hikida, Y, Kimoto, M, Hirao, I, Yokoyama, S. Deposit date: 2016-10-07 Release date: 2017-01-25 Last modified: 2017-08-30 Method: X-RAY DIFFRACTION (2.502 Å) Cite: Crystal structure of Deep Vent DNA polymerase. Biochem. Biophys. Res. Commun., 483, 2017
2VWJ	Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography. Descriptor: 5'-D(*AP*AP*UP*GP*GP*AP*GP*AP*CP*GP *GP*CP*TP*TP*TP*TP*GP*CP*CP*GP*TP*GP*TP*C)-3', DNA POLYMERASE, POTASSIUM ION Authors: Firbank, S.J, Wardle, J, Heslop, P, Lewis, R.J, Connolly, B.A. Deposit date: 2008-06-25 Release date: 2008-07-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Uracil Recognition in Archaeal DNA Polymerases Captured by X-Ray Crystallography. J.Mol.Biol., 381, 2008
2JGU	crystal structure of DNA-directed DNA polymerase Descriptor: DNA POLYMERASE, MANGANESE (II) ION Authors: Kim, D.U, Cho, H.S. Deposit date: 2007-02-15 Release date: 2008-04-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structure of Pfu, the High Fidelity DNA Polymerase from Pyrococcus Furiosus. Int.J.Biol.Macromol., 42, 2008
2VWK	Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography. V93Q polymerase variant Descriptor: DNA POLYMERASE, SODIUM ION, SULFATE ION Authors: Firbank, S.J, Wardle, J, Heslop, P, Lewis, R.J, Connolly, B.A. Deposit date: 2008-06-26 Release date: 2008-07-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Uracil Recognition in Archaeal DNA Polymerases Captured by X-Ray Crystallography. J.Mol.Biol., 381, 2008
1CLQ	CRYSTAL STRUCTURE OF A REPLICATION FORK DNA POLYMERASE EDITING COMPLEX AT 2.7 A RESOLUTION Descriptor: CALCIUM ION, DNA (5'-D(*AP*GP*TP*AP*GP*TP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*AP*CP*TP*AP*CP*T)-3'), ... Authors: Shamoo, Y, Steitz, T.A. Deposit date: 1999-04-30 Release date: 1999-10-28 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex. Cell(Cambridge,Mass.), 99, 1999
2XHB	Crystal structure of DNA polymerase from Thermococcus gorgonarius in complex with hypoxanthine-containing DNA Descriptor: 5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', DNA POLYMERASE, HYPOXANTHINE-CONTAINING DNA, ... Authors: Killelea, T, Ghosh, S, Tan, S.S, Heslop, P, Firbank, S.J, Kool, E.T, Connolly, B.A. Deposit date: 2010-06-14 Release date: 2010-07-21 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.72 Å) Cite: Probing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-Ray Crystallography and Non-Hydrogen Bonding Isosteric Base Analogues. Biochemistry, 49, 2010
1D5A	CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM Descriptor: MAGNESIUM ION, PROTEIN (DNA POLYMERASE), SULFATE ION Authors: Zhao, Y, Jeruzalmi, D, Leighton, L, Lasken, R, Kuriyan, J. Deposit date: 1999-10-06 Release date: 2000-03-24 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal structure of an archaebacterial DNA polymerase. Structure Fold.Des., 7, 1999
6G0A	The crystal structure of the Pol2 catalytic domain of DNA polymerase epsilon carrying a P301R substitution. Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*TP*AP*AP*CP*CP*GP*CP*GP*TP*TP*DC)-3'), ... Authors: Parkash, V, Johansson, E. Deposit date: 2018-03-16 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase epsilon. Nat Commun, 10, 2019
1S5J	Insight in DNA Replication: The crystal structure of DNA Polymerase B1 from the archaeon Sulfolobus solfataricus Descriptor: DNA polymerase I, MAGNESIUM ION, SULFATE ION Authors: Savino, C, Federici, L, Nastopoulos, V, Johnson, K.A, Pisani, F.M, Rossi, M, Tsernoglou, D. Deposit date: 2004-01-21 Release date: 2004-11-09 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Insights into DNA replication: the crystal structure of DNA polymerase B1 from the archaeon Sulfolobus solfataricus Structure, 12, 2004
6FWK	The crystal structure of Pol2CORE-M644G in complex with DNA and an incoming nucleotide Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*TP*AP*AP*CP*CP*GP*CP*GP*TP*TP*(DOC))-3'), ... Authors: Parkash, V, Johansson, E. Deposit date: 2018-03-06 Release date: 2019-01-30 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.503 Å) Cite: Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase epsilon. Nat Commun, 10, 2019
5IUD	Human DNA polymerase alpha in binary complex with a DNA:DNA template-primer Descriptor: DNA polymerase alpha catalytic subunit, DNA primer, DNA template Authors: Coloma, J, Aggarwal, A.K. Deposit date: 2016-03-17 Release date: 2016-04-13 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Human DNA polymerase alpha in binary complex with a DNA:DNA template-primer. Sci Rep, 6, 2016
3A2F	Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex Descriptor: DNA polymerase, DNA polymerase sliding clamp Authors: Nishida, H, Ishino, Y, Morikawa, K. Deposit date: 2009-05-15 Release date: 2009-11-03 Last modified: 2021-11-10 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Structural determinant for switching between the polymerase and exonuclease modes in the PCNA-replicative DNA polymerase complex To be Published
2GV9	Crystal structure of the Herpes Simplex virus type 1 DNA polymerase Descriptor: DNA polymerase, GUANIDINE, MERCURY (II) ION, ... Authors: Liu, S. Deposit date: 2006-05-02 Release date: 2006-05-16 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Crystal structure of the herpes simplex virus 1 DNA polymerase. J.Biol.Chem., 281, 2006
1IG9	Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase Descriptor: 5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*(DOC))-3', CALCIUM ION, ... Authors: Franklin, M.C, Wang, J, Steitz, T.A. Deposit date: 2001-04-17 Release date: 2001-06-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
1TGO	THERMOSTABLE B TYPE DNA POLYMERASE FROM THERMOCOCCUS GORGONARIUS Descriptor: PROTEIN (THERMOSTABLE B DNA POLYMERASE) Authors: Hopfner, K.-P, Eichinger, A, Engh, R.A, Laue, F, Ankenbauer, W, Huber, R, Angerer, B. Deposit date: 1999-02-23 Release date: 1999-03-22 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius. Proc.Natl.Acad.Sci.USA, 96, 1999
9ENP	HSV-1 DNA polymerase-processivity factor complex in exonuclease state with 1-bp DNA mismatch Descriptor: CALCIUM ION, DNA (46-MER), DNA (67-MER), ... Authors: Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. Deposit date: 2024-03-13 Release date: 2024-05-29 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.12 Å) Cite: Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 2024

 

12345678910111213>