5EXR

Crystal structure of human primosome

Summary for 5EXR

• Entry DOI: 10.2210/pdb5exr/pdb
• Descriptor: DNA primase small subunit, DNA primase large subunit, DNA polymerase alpha catalytic subunit, ... (6 entities in total)
• Functional Keywords: human primosome, complex, primase, dna polymerase alpha, primer, dna replication, dna, rna, replicase, replication
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 609225.83

Authors

Tahirov, T.H.,Baranovskiy, A.G.,Babayeva, N.D. (deposition date: 2015-11-24, release date: 2016-03-23, Last modification date: 2023-09-27)

• Primary citation: Baranovskiy, A.G.,Babayeva, N.D.,Zhang, Y.,Gu, J.,Suwa, Y.,Pavlov, Y.I.,Tahirov, T.H.; Mechanism of Concerted RNA-DNA Primer Synthesis by the Human Primosome.; J.Biol.Chem., 291:10006-10020, 2016; PubMed: 26975377; DOI: 10.1074/jbc.M116.717405

Experimental method

X-RAY DIFFRACTION (3.6 Å)