5EXR
Crystal structure of human primosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E | DNA primase small subunit | polymer | 420 | 49981.0 | 2 | UniProt (P49642) Pfam (PF01896) In PDB | Homo sapiens (Human) | DNA primase 49 kDa subunit,p49 |
| 2 | B, F | DNA primase large subunit | polymer | 509 | 58890.9 | 2 | UniProt (P49643) Pfam (PF04104) In PDB | Homo sapiens (Human) | DNA primase 58 kDa subunit,p58 |
| 3 | C, G | DNA polymerase alpha catalytic subunit | polymer | 1128 | 129308.8 | 2 | UniProt (P09884) Pfam (PF03104) Pfam (PF00136) Pfam (PF08996) In PDB | Homo sapiens (Human) | DNA polymerase alpha catalytic subunit p180 |
| 4 | D, H | DNA polymerase alpha subunit B | polymer | 597 | 65884.3 | 2 | UniProt (Q14181) Pfam (PF08418) Pfam (PF04042) In PDB | Homo sapiens (Human) | DNA polymerase alpha 70 kDa subunit |
| 5 | A, C, E, G | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 6 | B, F | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 2 | Chemie (SF4) |
Sequence modifications
C, G: 335 - 1462 (UniProt: P09884)
| PDB | External Database | Details |
|---|---|---|
| Ala 516 | Val 516 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 608130.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1095.7 | |
| All* | Total formula weight | 609225.8 |
