PDB: 164 件ウェブページステータス検索Chemie searchBIRD

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2LPC	NMR STRUCTURE of Bcl-XL 分子名称: Bcl-2-like protein 1 著者 Wysoczanski, P, Mart, R.J, Loveridge, J.E, Williams, C, Whittaker, S.B.-M, Crump, M.P, Allemann, R.K. 登録日 2012-02-09 公開日 2012-03-21 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR Solution Structure of a Photoswitchable Apoptosis Activating Bak Peptide Bound to Bcl-x(L). J.Am.Chem.Soc., 134, 2012
2ME9	Solution structure of BCL-xL containing the alpha1-alpha2 disordered loop determined with selective isotope labelling of I,L,V sidechains 分子名称: Bcl-2-like protein 1 著者 Viacava Follis, A, Grace, C.R, Kriwacki, R.W. 登録日 2013-09-25 公開日 2014-04-30 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nat.Struct.Mol.Biol., 21, 2014
2ME8	Solution Structure of BCL-xL in its p53-bound conformation determined with selective isotope labelling of I,L,V sidechains 分子名称: Bcl-2-like protein 1 著者 Viacava Follis, A, Grace, C.R, Kriwacki, R.W. 登録日 2013-09-25 公開日 2014-04-30 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nat.Struct.Mol.Biol., 21, 2014
2M04	Solution structure of BCL-xL in complex with PUMA BH3 peptide 分子名称: Bcl-2-binding component 3, Bcl-2-like protein 1 著者 Viacava Follis, A, Royappa, G, Kriwacki, R.W. 登録日 2012-10-19 公開日 2013-01-30 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis. Nat.Chem.Biol., 9, 2013
2M03	Solution structure of BCL-xL determined with selective isotope labelling of I,L,V sidechains 分子名称: Bcl-2-like protein 1 著者 Viacava Follis, A, Royappa, G, Kriwacki, R.W. 登録日 2012-10-19 公開日 2013-01-30 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis. Nat.Chem.Biol., 9, 2013
2O2F	Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand 分子名称: 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE, Apoptosis regulator Bcl-2 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-29 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2O21	Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand 分子名称: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-2 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-29 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2O2N	Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand 分子名称: 4-[4-(BIPHENYL-2-YLMETHYL)PIPERAZIN-1-YL]-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE, Apoptosis regulator Bcl-X 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-30 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2O22	Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand 分子名称: Apoptosis regulator Bcl-2, N-[(4-{[1,1-dimethyl-2-(phenylthio)ethyl]amino}-3-nitrophenyl)sulfonyl]-4-(4,4-dimethylpiperidin-1-yl)benzamide 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-29 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2P1L	Structure of the Bcl-XL:Beclin 1 complex 分子名称: Apoptosis regulator Bcl-X, Beclin 1 著者 Jeffrey, P.D, Shi, Y, Oberstein, A.L. 登録日 2007-03-05 公開日 2007-03-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein J.Biol.Chem., 282, 2007
2O1Y	Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand 分子名称: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-X 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-29 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2O2M	Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand 分子名称: 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE, Apoptosis regulator Bcl-X 著者 Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W. 登録日 2006-11-30 公開日 2007-02-27 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL. J.Med.Chem., 50, 2007
2PON	Solution structure of the Bcl-xL/Beclin-1 complex 分子名称: Apoptosis regulator Bcl-X, Beclin-1 著者 Feng, W, Huang, S, Wu, H, Zhang, M. 登録日 2007-04-27 公開日 2007-09-04 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Molecular Basis of Bcl-xL's Target Recognition Versatility Revealed by the Structure of Bcl-xL in Complex with the BH3 Domain of Beclin-1. J.Mol.Biol., 372, 2007
2MEJ	Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints 分子名称: Bcl-2-like protein 1, Cellular tumor antigen p53, ZINC ION 著者 Viacava Follis, A, Grace, C.R, Kriwacki, R.W. 登録日 2013-09-25 公開日 2014-04-30 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The DNA-binding domain mediates both nuclear and cytosolic functions of p53. Nat.Struct.Mol.Biol., 21, 2014

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