PDB: 2435 件ウェブページステータス検索Chemie searchBIRD

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6E23	Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-[(3,4-dichlorophenyl)methyl]-3-(6-fluoro-2-methylpyridin-3-yl)-5-{[(2E)-2-imino-3-methyl-2,3-dihydro-1H-imidazol-1-yl]methyl}benzamide, WD repeat-containing protein 5 著者 Phan, J, Fesik, S.W. 登録日 2018-07-10 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Rep, 26, 2019
6E22	Displacement of WDR5 from chromatin by a pharmacological WIN site inhibitor with picomolar affinity 分子名称: 3-{[(4,5-dihydro-1H-imidazol-2-yl)amino]methyl}-N-[(3,5-dimethoxyphenyl)methyl]-4-fluorobenzamide, SULFATE ION, WD repeat-containing protein 5 著者 Phan, J, Fesik, S.W. 登録日 2018-07-10 公開日 2019-03-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Rep, 26, 2019
6E29	Crystal structure of Myceliophteria_thermophila Cps50 (Swd1) beta-propeller domain 分子名称: SWD1-like protein 著者 Joshi, M, Yang, Y, Brunzelle, J.S, Couture, J.F. 登録日 2018-07-10 公開日 2018-07-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.818 Å) 主引用文献 Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex. Cell, 174, 2018
2O9K	WDR5 in Complex with Dimethylated H3K4 Peptide 分子名称: H3 HISTONE, WD repeat protein 5 著者 Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) 登録日 2006-12-13 公開日 2006-12-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for Molecular Recognition and Presentation of Histone H3 by Wdr5. Embo J., 25, 2006
2PM9	Crystal structure of yeast Sec13/31 vertex element of the COPII vesicular coat 分子名称: Protein transport protein SEC13, Protein transport protein SEC31 著者 Goldberg, J, Fath, S, Mancias, J.D, Bi, X. 登録日 2007-04-20 公開日 2007-07-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure and Organization of Coat Proteins in the COPII Cage. Cell(Cambridge,Mass.), 129, 2007
3EMH	Structural basis of WDR5-MLL interaction 分子名称: Mixed-lineage leukemia protein 1, SULFATE ION, WD repeat-containing protein 5 著者 Song, J.J, Kingston, R.E. 登録日 2008-09-24 公開日 2008-10-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 WDR5 Interacts with Mixed Lineage Leukemia (MLL) Protein via the Histone H3-binding Pocket. J.Biol.Chem., 283, 2008
3EG6	Structure of WDR5 bound to MLL1 peptide 分子名称: MLL-1 peptide, SULFATE ION, WD repeat-containing protein 5 著者 Patel, A, Dharmarajan, V, Cosgrove, M.S. 登録日 2008-09-10 公開日 2008-09-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide. J.Biol.Chem., 283, 2008
3FM0	Crystal structure of WD40 protein Ciao1 分子名称: Protein CIAO1, SULFATE ION 著者 Dong, A, Ravichandran, M, Crombet, L, Cossar, D, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) 登録日 2008-12-19 公開日 2009-02-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure and function of WD40 domain proteins. Protein Cell, 2, 2011
3FRX	Crystal Structure of the Yeast Orthologue of RACK1, Asc1. 分子名称: Guanine nucleotide-binding protein subunit beta-like protein, MANGANESE (II) ION 著者 Coyle, S.M, Gilbert, W.V, Doudna, J.A. 登録日 2009-01-08 公開日 2009-02-17 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Direct link between RACK1 function and localization at the ribosome in vivo Mol.Cell.Biol., 29, 2009
4Y7R	Crystal structure of WDR5 in complex with MYC MbIIIb peptide 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MYC MbIIIb peptide, ... 著者 Sun, Q, Phan, J, Olejniczak, E.T, Thomas, L.R, Fesik, S.W, Tansey, W.P. 登録日 2015-02-16 公開日 2015-04-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC. Mol.Cell, 58, 2015
4CY3	Crystal structure of the NSL1-WDS complex. 分子名称: CG4699, ISOFORM D, GLYCEROL, ... 著者 Dias, J, Brettschneider, J, Cusack, S, Kadlec, J. 登録日 2014-04-10 公開日 2014-05-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex. Genes Dev., 28, 2014
4CY5	Crystal structure of the NSL1-WDS-NSL2 complex. 分子名称: CG4699, ISOFORM D, DIM GAMMA-TUBULIN 1, ... 著者 Dias, J, Brettschneider, J, Cusack, S, Kadlec, J. 登録日 2014-04-10 公開日 2014-05-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex. Genes Dev., 28, 2014
4YVD	Crytsal structure of human Pleiotropic Regulator 1 (PRL1) 分子名称: CHLORIDE ION, Pleiotropic regulator 1, SODIUM ION, ... 著者 Dong, A, Zeng, H, Xu, C, Tempel, W, Li, Y, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Wu, H, Structural Genomics Consortium (SGC) 登録日 2015-03-19 公開日 2015-04-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crytsal structure of human Pleiotropic Regulator 1 (PRL1). to be published
4CY1	Crystal structure of the KANSL1-WDR5 complex. 分子名称: GLYCEROL, KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, WD REPEAT-CONTAINING PROTEIN 5 著者 Dias, J, Brettschneider, J, Cusack, S, Kadlec, J. 登録日 2014-04-09 公開日 2014-05-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex. Genes Dev., 28, 2014
4D6V	Crystal structure of signal transducing protein 分子名称: G PROTEIN BETA SUBUNIT GIB2 著者 Ero, R, Dimitrova, V.T, Chen, Y, Bu, W, Feng, S, Liu, T, Wang, P, Xue, C, Tan, S.M, Gao, Y.G. 登録日 2014-11-17 公開日 2015-03-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Gib2, a Signal-Transducing Protein Scaffold Associated with Ribosomes in Cryptococcus Neoformans. Sci.Rep., 5, 2015
4CY2	Crystal structure of the KANSL1-WDR5-KANSL2 complex. 分子名称: KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, KAT8 REGULATORY NSL COMPLEX SUBUNIT 2, WD REPEAT-CONTAINING PROTEIN 5 著者 Dias, J, Brettschneider, J, Cusack, S, Kadlec, J. 登録日 2014-04-09 公開日 2014-05-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex. Genes Dev., 28, 2014
4ZOV	Crystal structure of the Saccharomyces cerevisiae Sqt1 分子名称: Ribosome assembly protein SQT1 著者 Pausch, P, Altegoer, F, Bange, G. 登録日 2015-05-07 公開日 2015-07-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones. Nat Commun, 6, 2015
4ZN4	Crystal structure of Sqt1 from Chaetomium thermophilum solved by MR 分子名称: GLYCEROL, SULFATE ION, sqt1 著者 Ahmed, Y.L, Sinning, I. 登録日 2015-05-04 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones. Nat Commun, 6, 2015
4ZOZ	Crystal structure of the Chaetomium thermophilum Sqt1 bound to the N-terminus of the ribosomal protein L10 分子名称: 60S ribosomal protein L10-like protein, Sqt1 著者 Pausch, P, Altegoer, F, Bange, G. 登録日 2015-05-07 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones. Nat Commun, 6, 2015
4ZOX	Crystal structure of the Saccharomyces cerevisiae Sqt1 bound to the N-terminus of the ribosomal protein L10 分子名称: 60S ribosomal protein L10, Ribosome assembly protein SQT1 著者 Pausch, P, Altegoer, F, Bange, G. 登録日 2015-05-07 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones. Nat Commun, 6, 2015
4BH6	Insights into degron recognition by APC coactivators from the structure of an Acm1-Cdh1 complex 分子名称: APC/C ACTIVATOR PROTEIN CDH1, APC/C-CDH1 MODULATOR 1 著者 He, J, Chao, W.C.H, Zhang, Z, Yang, J, Cronin, N, Barford, D. 登録日 2013-03-29 公開日 2013-06-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Insights Into Degron Recognition by Apc/C Coactivators from the Structure of an Acm1-Cdh1 Complex. Mol.Cell, 50, 2013
4ZOY	Crystal structure of the Chaetomium thermophilum Sqt1 分子名称: Sqt1 著者 Pausch, P, Altegoer, F, Bange, G. 登録日 2015-05-07 公開日 2015-07-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Co-translational capturing of nascent ribosomal proteins by their dedicated chaperones. Nat Commun, 6, 2015
4ES0	X-ray structure of WDR5-SETd1b Win motif peptide binary complex 分子名称: Histone-lysine N-methyltransferase SETD1B, WD repeat-containing protein 5 著者 Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. 登録日 2012-04-21 公開日 2012-05-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.817 Å) 主引用文献 Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012
4ERZ	X-ray structure of WDR5-MLL4 Win motif peptide binary complex 分子名称: Histone-lysine N-methyltransferase MLL4, WD repeat-containing protein 5 著者 Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. 登録日 2012-04-21 公開日 2012-05-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012
4EWR	X-ray structure of WDR5-SETd1a Win motif peptide binary complex 分子名称: Histone-lysine N-methyltransferase SETD1A, WD repeat-containing protein 5 著者 Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. 登録日 2012-04-27 公開日 2012-05-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.503 Å) 主引用文献 Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J.Biol.Chem., 287, 2012

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