3EMH
Structural basis of WDR5-MLL interaction
Summary for 3EMH
Entry DOI | 10.2210/pdb3emh/pdb |
Descriptor | WD repeat-containing protein 5, Mixed-lineage leukemia protein 1, SULFATE ION, ... (4 entities in total) |
Functional Keywords | chromatin, histone, wd40 repeat, nucleus, phosphoprotein, wd repeat, zinc-finger, gene regulation |
Biological source | Homo sapiens More |
Cellular location | Nucleus: P61964 |
Total number of polymer chains | 2 |
Total formula weight | 36612.42 |
Authors | Song, J.J.,Kingston, R.E. (deposition date: 2008-09-24, release date: 2008-10-07, Last modification date: 2023-09-06) |
Primary citation | Song, J.J.,Kingston, R.E. WDR5 Interacts with Mixed Lineage Leukemia (MLL) Protein via the Histone H3-binding Pocket. J.Biol.Chem., 283:35258-35264, 2008 Cited by PubMed: 18840606DOI: 10.1074/jbc.M806900200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.37 Å) |
Structure validation
Download full validation report