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3EG6

Structure of WDR5 bound to MLL1 peptide

Summary for 3EG6
Entry DOI10.2210/pdb3eg6/pdb
DescriptorWD repeat-containing protein 5, MLL-1 peptide, SULFATE ION, ... (4 entities in total)
Functional Keywordswdr5, mll1, win motif, mll core complex, histone h3, lysine methylation, nucleus, phosphoprotein, wd repeat, protein binding
Biological sourceHomo sapiens (human)
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Cellular locationNucleus : P61964
Nucleus . MLL cleavage product N320: Nucleus. MLL cleavage product C180: Nucleus: Q03164
Total number of polymer chains2
Total formula weight35932.64
Authors
Patel, A.,Dharmarajan, V.,Cosgrove, M.S. (deposition date: 2008-09-10, release date: 2008-09-30, Last modification date: 2023-08-30)
Primary citationPatel, A.,Dharmarajan, V.,Cosgrove, M.S.
Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide.
J.Biol.Chem., 283:32158-32161, 2008
Cited by
PubMed: 18829459
DOI: 10.1074/jbc.C800164200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.72 Å)
Structure validation

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