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4Z9E
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BU of 4z9e by Molmil
Alba from Thermoplasma volcanium
Descriptor: DNA/RNA-binding protein Alba
Authors:Ma, C, Lee, S.J, Pathak, C, Lee, B.J.
Deposit date:2015-04-10
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Alba from Thermoplasma volcanium belongs to alpha-NAT's: An insight into the structural aspects of Tv Alba and its acetylation by Tv Ard1.
Arch.Biochem.Biophys., 590, 2016
5H4P
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BU of 5h4p by Molmil
Structural snapshot of cytoplasmic pre-60S ribosomal particles bound with Nmd3, Lsg1, Tif6 and Reh1
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Ma, C, Wu, S, Li, N, Chen, Y, Yan, K, Li, Z, Zheng, L, Lei, J, Woolford, J.L, Gao, N.
Deposit date:2016-11-01
Release date:2017-01-25
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structural snapshot of cytoplasmic pre-60S ribosomal particles bound by Nmd3, Lsg1, Tif6 and Reh1
Nat. Struct. Mol. Biol., 24, 2017
5H5U
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BU of 5h5u by Molmil
Mechanistic insights into the alternative translation termination by ArfA and RF2
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Ma, C, Kurita, D, Li, N, Chen, Y, Himeno, H, Gao, N.
Deposit date:2016-11-09
Release date:2017-01-25
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanistic insights into the alternative translation termination by ArfA and RF2
Nature, 541, 2017
4PV6
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BU of 4pv6 by Molmil
Crystal Structure Analysis of Ard1 from Thermoplasma volcanium
Descriptor: ACETYL COENZYME *A, COENZYME A, N-terminal acetyltransferase complex subunit [ARD1]
Authors:Ma, C, Lee, S.J, Lee, B.J.
Deposit date:2014-03-15
Release date:2015-01-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structure of Thermoplasma volcanium Ard1 belongs to N-acetyltransferase family member suggesting multiple ligand binding modes with acetyl coenzyme A and coenzyme A.
Biochim.Biophys.Acta, 1844, 2014
6K6U
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BU of 6k6u by Molmil
Crystal structure of the human YTHDC2 YTH domain
Descriptor: 3'-5' RNA helicase YTHDC2
Authors:Ma, C, Liao, S, Xu, C.
Deposit date:2019-06-04
Release date:2019-12-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of human YTHDC2 YTH domain.
Biochem.Biophys.Res.Commun., 518, 2019
2L2I
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BU of 2l2i by Molmil
NMR Structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of EKLF
Descriptor: Krueppel-like factor 1, RNA polymerase II transcription factor B subunit 1
Authors:Mas, C, Di Lello, P, Lafrance-Vanasse, J, Omichinski, J.G.
Deposit date:2010-08-18
Release date:2011-07-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR Structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of EKLF
To be Published
4PQP
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BU of 4pqp by Molmil
Crystal structure of human SNX14 PX domain in space group P43212
Descriptor: GLYCEROL, Sorting nexin-14
Authors:Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B.
Deposit date:2014-03-03
Release date:2014-09-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
4PQO
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BU of 4pqo by Molmil
Structure of the human SNX14 PX domain in space group I41
Descriptor: Sorting nexin-14
Authors:Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B.
Deposit date:2014-03-03
Release date:2014-09-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
6WTT
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BU of 6wtt by Molmil
Crystals Structure of the SARS-CoV-2 (COVID-19) main protease with inhibitor GC-376
Descriptor: (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ...
Authors:Sacco, M, Ma, C, Chen, Y, Wang, J.
Deposit date:2020-05-03
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease.
Cell Res., 30, 2020
2KI2
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BU of 2ki2 by Molmil
Solution Structure of ss-DNA Binding Protein 12RNP2 Precursor, HP0827(O25501_HELPY) form Helicobacter pylori
Descriptor: Ss-DNA binding protein 12RNP2
Authors:Ma, C, Lee, J, Kim, J, Park, S, Kwon, A, Lee, B.
Deposit date:2009-04-20
Release date:2009-10-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR solution structure of HP0827 (O25501_HELPY) from Helicobacter pylori: model of the possible RNA-binding site
J.Biochem., 146, 2009
7JRN
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BU of 7jrn by Molmil
Crystal structure of the wild type SARS-CoV-2 papain-like protease (PLPro) with inhibitor GRL0617
Descriptor: 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, SULFATE ION, ...
Authors:Sacco, M, Ma, C, Wang, J, Chen, Y.
Deposit date:2020-08-12
Release date:2020-08-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay.
Acs Cent.Sci., 7, 2021
5WOE
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BU of 5woe by Molmil
Solution structure of the sorting nexin 25 phox-homology domain
Descriptor: Sorting nexin-25
Authors:Chin, Y.K.Y, Mas, C, Mobli, M, Collins, B.M.
Deposit date:2017-08-01
Release date:2018-08-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
6XBI
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BU of 6xbi by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW248
Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Sacco, M, Ma, C, Wang, J, Chen, Y.
Deposit date:2020-06-06
Release date:2020-06-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L.
Sci Adv, 6, 2020
6XFN
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BU of 6xfn by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with UAW243
Descriptor: 3C-like proteinase, GLYCEROL, UAW243
Authors:Sacco, M, Ma, C, Wang, J, Chen, Y.
Deposit date:2020-06-15
Release date:2020-06-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L.
Sci Adv, 6, 2020
6XBH
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BU of 6xbh by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW247
Descriptor: 3C-like proteinase, GLYCEROL, SODIUM ION, ...
Authors:Sacco, M, Ma, C, Wang, J, Chen, Y.
Deposit date:2020-06-06
Release date:2020-06-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L.
Sci Adv, 6, 2020
6XBG
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BU of 6xbg by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAW246
Descriptor: 3C-like proteinase, GLYCEROL, SODIUM ION, ...
Authors:Sacco, M, Ma, C, Wang, J, Chen, Y.
Deposit date:2020-06-05
Release date:2020-06-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L.
Sci Adv, 6, 2020
6XA4
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BU of 6xa4 by Molmil
Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with UAW241
Descriptor: 3C-like proteinase, GLYCEROL, inhibitor UAW241
Authors:Sacco, M, Ma, C, Wang, J, Chen, Y.
Deposit date:2020-06-03
Release date:2020-06-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L.
Sci Adv, 6, 2020
4NPN
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BU of 4npn by Molmil
Crystal structure of human tetra-SUMO-2
Descriptor: Small ubiquitin-related modifier 2
Authors:Kung, C.C.-H, Naik, M.T, Chen, C.L, Ma, C, Huang, T.H.
Deposit date:2013-11-22
Release date:2014-10-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.633 Å)
Cite:Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain.
Biochem.J., 462, 2014
4Y21
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BU of 4y21 by Molmil
Crystal Structure of Munc13-1 MUN domain
Descriptor: Protein unc-13 homolog A
Authors:Yang, X.Y, Wang, S, Sheng, Y, Zhang, M, Zou, W.J, Wu, L.J, Kang, L.J, Rizo, J, Zhang, R.G, Xu, T, Ma, C.
Deposit date:2015-02-09
Release date:2015-06-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming.
Nat.Struct.Mol.Biol., 22, 2015
6LU8
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BU of 6lu8 by Molmil
Cryo-EM structure of a human pre-60S ribosomal subunit - state A
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
Deposit date:2020-01-26
Release date:2020-08-26
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
6LPC
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BU of 6lpc by Molmil
Crystal Structure of rat Munc18-1 with K332E/K333E mutation
Descriptor: Syntaxin-binding protein 1
Authors:Wang, X.P, Gong, J.H, Wang, S, Zhu, L, Yang, X.Y, Xu, Y.Y, Yang, X.F, Ma, C.
Deposit date:2020-01-09
Release date:2020-07-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.402 Å)
Cite:Munc13 activates the Munc18-1/syntaxin-1 complex and enables Munc18-1 to prime SNARE assembly.
Embo J., 39, 2020
7PEG
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BU of 7peg by Molmil
Structure of the sporulation/germination protein YhcN from Bacillus subtilis
Descriptor: Probable spore germination lipoprotein YhcN
Authors:Liu, B, Chan, H, Bauda, E, Contreras-Martel, C, Bellard, L, Villard, A.M, Mas, C, Neumann, E, Fenel, D, Favier, A, Serrano, M, Henriques, A.O.H, Rodrigues, C.D.A, Morlot, C.
Deposit date:2021-08-10
Release date:2022-08-24
Last modified:2022-09-07
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural insights into ring-building motif domains involved in bacterial sporulation.
J.Struct.Biol., 214, 2022
2XA8
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BU of 2xa8 by Molmil
Crystal structure of the Fab domain of omalizumab at 2.41A
Descriptor: OMALIZUMAB HEAVY CHAIN, OMALIZUMAB LIGHT CHAIN
Authors:Huang, C.H, Hung, F.H.A, Lim, C, Chang, T.W, Ma, C.
Deposit date:2010-03-30
Release date:2011-05-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural and Physical Basis for Anti-IgE Therapy.
Sci Rep, 5, 2015
6GZ8
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BU of 6gz8 by Molmil
First GerMN domain of the sporulation protein GerM from Bacillus subtilis
Descriptor: 1,2-ETHANEDIOL, SODIUM ION, Spore germination protein GerM
Authors:Trouve, J, Mohamed, A, Leisico, F, Contreras-Martel, C, Liu, B, Mas, C, Rudner, D.Z, Rodrigues, C.D.A, Morlot, C.
Deposit date:2018-07-03
Release date:2018-10-10
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural characterization of the sporulation protein GerM from Bacillus subtilis.
J. Struct. Biol., 204, 2018
6GZB
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BU of 6gzb by Molmil
Tandem GerMN domains of the sporulation protein GerM from Bacillus subtilis
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Spore germination protein GerM
Authors:Trouve, J, Mohamed, A, Leisico, F, Contreras-Martel, C, Liu, B, Mas, C, Rudner, D.Z, Rodrigues, C.D.A, Morlot, C.
Deposit date:2018-07-03
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural characterization of the sporulation protein GerM from Bacillus subtilis.
J. Struct. Biol., 204, 2018

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