5FGM
| Streptomyces coelicolor SigR region 4 | Descriptor: | ECF RNA polymerase sigma factor SigR | Authors: | Park, S.Y. | Deposit date: | 2015-12-21 | Release date: | 2016-03-02 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | In Streptomyces coelicolor SigR, methionine at the -35 element interacting region 4 confers the -31'-adenine base selectivity Biochem.Biophys.Res.Commun., 470, 2016
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5X14
| Crystal structure of Bacillus subtilis PadR in complex with ferulic acid | Descriptor: | 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, GLYCEROL, Transcriptional regulator | Authors: | Park, S.C, Kwak, Y.M, Song, W.S, Hong, M, Yoon, S.I. | Deposit date: | 2017-01-24 | Release date: | 2017-11-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural basis of effector and operator recognition by the phenolic acid-responsive transcriptional regulator PadR Nucleic Acids Res., 45, 2017
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5X13
| Crystal structure of Bacillus subtilis PadR in complex with p-coumaric acid | Descriptor: | 4'-HYDROXYCINNAMIC ACID, GLYCEROL, Transcriptional regulator | Authors: | Park, S.C, Kwak, Y.M, Song, W.S, Hong, M, Yoon, S.I. | Deposit date: | 2017-01-24 | Release date: | 2017-11-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of effector and operator recognition by the phenolic acid-responsive transcriptional regulator PadR Nucleic Acids Res., 45, 2017
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2KSJ
| Structure and Dynamics of the Membrane-bound form of Pf1 Coat Protein: Implications for Structural Rearrangement During Virus Assembly | Descriptor: | Capsid protein G8P | Authors: | Park, S, Marassi, F, Black, D, Opella, S.J. | Deposit date: | 2010-01-05 | Release date: | 2010-11-10 | Last modified: | 2024-05-01 | Method: | SOLID-STATE NMR, SOLUTION NMR | Cite: | Structure and dynamics of the membrane-bound form of Pf1 coat protein: implications of structural rearrangement for virus assembly. Biophys.J., 99, 2010
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8KCA
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8EY0
| Structure of an orthogonal PYR1*:HAB1* chemical-induced dimerization module in complex with mandipropamid | Descriptor: | (2S)-2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)ethanamide, Abscisic acid receptor PYR1, GLYCEROL, ... | Authors: | Park, S.-Y, Volkman, B.F, Cutler, S.R, Peterson, F.C. | Deposit date: | 2022-10-26 | Release date: | 2023-11-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | An orthogonalized PYR1-based CID module with reprogrammable ligand-binding specificity. Nat.Chem.Biol., 20, 2024
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6PWW
| Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome | Descriptor: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | Deposit date: | 2019-07-23 | Release date: | 2019-12-18 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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6PWV
| Cryo-EM structure of MLL1 core complex bound to the nucleosome | Descriptor: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | Deposit date: | 2019-07-23 | Release date: | 2019-12-18 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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6PWX
| Cryo-EM structure of RbBP5 bound to the nucleosome | Descriptor: | DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Park, S.H, Ayoub, A, Lee, Y.T, Xu, J, Zhang, W, Zhang, B, Zhang, Y, Cianfrocco, M.A, Su, M, Dou, Y, Cho, U. | Deposit date: | 2019-07-23 | Release date: | 2019-12-18 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-EM structure of the human MLL1 core complex bound to the nucleosome. Nat Commun, 10, 2019
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2KNH
| The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide | Descriptor: | Protein CBFA2T1, Transcription factor 12 | Authors: | Park, S, Cierpicki, T, Tonelli, M, Bushweller, J.H. | Deposit date: | 2009-08-25 | Release date: | 2009-10-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity. Blood, 113, 2009
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6W5N
| Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05) | Descriptor: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. | Deposit date: | 2020-03-13 | Release date: | 2021-03-31 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
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6W5I
| Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class01) | Descriptor: | DNA (147-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. | Deposit date: | 2020-03-13 | Release date: | 2021-03-31 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
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6W5M
| Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02) | Descriptor: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Park, S.H, Lee, Y.T, Ayoub, A, Dou, Y, Cho, U. | Deposit date: | 2020-03-13 | Release date: | 2021-03-31 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin. Nat Commun, 12, 2021
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2KYU
| The solution structure of the PHD3 finger of MLL | Descriptor: | Histone-lysine N-methyltransferase MLL, ZINC ION | Authors: | Park, S, Bushweller, J.H. | Deposit date: | 2010-06-08 | Release date: | 2010-08-25 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression. Biochemistry, 49, 2010
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5JE8
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2KYX
| Solution structure of the RRM domain of CYP33 | Descriptor: | Peptidyl-prolyl cis-trans isomerase E | Authors: | Park, S, Bushweller, J.H. | Deposit date: | 2010-06-09 | Release date: | 2010-08-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression . Biochemistry, 49, 2010
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5GV5
| Crystal structure of Candida antarctica Lipase B with active Ser105 modified with a phosphonate inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lipase B, ... | Authors: | Park, S.Y, Lee, H. | Deposit date: | 2016-09-02 | Release date: | 2017-09-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Structural and Experimental Evidence for the Enantiomeric Recognition toward a Bulky sec-Alcohol by Candida antarctica Lipase B Acs Catalysis, 6, 2016
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5CSS
| Crystal structure of triosephosphate isomerase from Thermoplasma acidophilum with glycerol 3-phosphate | Descriptor: | CHLORIDE ION, SN-GLYCEROL-3-PHOSPHATE, Triosephosphate isomerase | Authors: | Park, S.H, Kim, H.S, Song, M.K, Kim, K.R, Park, J.S, Han, B.W. | Deposit date: | 2015-07-23 | Release date: | 2016-06-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structure and Stability of the Dimeric Triosephosphate Isomerase from the Thermophilic Archaeon Thermoplasma acidophilum. Plos One, 10, 2015
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5CSR
| Crystal structure of triosephosphate isomerase from Thermoplasma acidophilium | Descriptor: | CHLORIDE ION, GLYCEROL, Triosephosphate isomerase | Authors: | Park, S.H, Kim, H.S, Song, M.K, Park, H.S, Han, B.W. | Deposit date: | 2015-07-23 | Release date: | 2016-06-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structure and Stability of the Dimeric Triosephosphate Isomerase from the Thermophilic Archaeon Thermoplasma acidophilum. Plos One, 10, 2015
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8SQG
| OXA-48 bound to inhibitor CDD-2801 | Descriptor: | (1M)-3'-(benzyloxy)-5-[2-(methylamino)-2-oxoethoxy][1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | Authors: | Park, S, Judge, A, Fan, J, Sankaran, B, Palzkill, T. | Deposit date: | 2023-05-04 | Release date: | 2024-01-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library. J.Med.Chem., 67, 2024
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4RDH
| Crystal structure of E. coli tRNA N6-threonylcarbamoyladenosine dehydratase, TcdA | Descriptor: | ADENOSINE MONOPHOSPHATE, GLYCEROL, SULFATE ION, ... | Authors: | Park, S.Y, Kim, S, Lee, H. | Deposit date: | 2014-09-19 | Release date: | 2015-08-05 | Last modified: | 2015-10-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Structure of Escherichia coli TcdA (Also Known As CsdL) Reveals a Novel Topology and Provides Insight into the tRNA Binding Surface Required for N(6)-Threonylcarbamoyladenosine Dehydratase Activity. J.Mol.Biol., 427, 2015
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8SQF
| OXA-48 bound to inhibitor CDD-2725 | Descriptor: | (1M)-3'-(benzyloxy)-5-hydroxy[1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | Authors: | Park, S, Judge, A, Fan, J, Sankaran, B, Prasad, B.V.V, Palzkill, T. | Deposit date: | 2023-05-04 | Release date: | 2024-01-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library. J.Med.Chem., 67, 2024
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4RDI
| Crystal structure of E. coli tRNA N6-threonylcarbamoyladenosine dehydratase, TcdA | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, tRNA threonylcarbamoyladenosine dehydratase | Authors: | Park, S.Y, Kim, S, Lee, H. | Deposit date: | 2014-09-19 | Release date: | 2015-08-05 | Last modified: | 2015-10-07 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Structure of Escherichia coli TcdA (Also Known As CsdL) Reveals a Novel Topology and Provides Insight into the tRNA Binding Surface Required for N(6)-Threonylcarbamoyladenosine Dehydratase Activity. J.Mol.Biol., 427, 2015
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4N7V
| Crystal structure of human Plk4 cryptic polo box (CPB) in complex with a Cep152 N-terminal fragment | Descriptor: | Centrosomal protein of 152 kDa, Serine/threonine-protein kinase PLK4 | Authors: | Park, S.-Y, Park, J.-E, Tian, L, Kim, T.-S, Yang, W, Lee, K.S. | Deposit date: | 2013-10-16 | Release date: | 2014-07-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.758 Å) | Cite: | Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis. Nat.Struct.Mol.Biol., 21, 2014
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4N7Z
| Crystal structure of human Plk4 cryptic polo box (CPB) in complex with a Cep192 N-terminal fragment | Descriptor: | Centrosomal protein of 192 kDa, Serine/threonine-protein kinase PLK4 | Authors: | Park, S.-Y, Park, J.-E, Tian, L, Kim, T.-S, Yang, W, Lee, K.S. | Deposit date: | 2013-10-16 | Release date: | 2014-07-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis. Nat.Struct.Mol.Biol., 21, 2014
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