4PQO

Structure of the human SNX14 PX domain in space group I41

Summary for 4PQO

• Entry DOI: 10.2210/pdb4pqo/pdb
• Related: 4PQP
• Descriptor: Sorting nexin-14 (2 entities in total)
• Functional Keywords: sorting nexin, phox homology domain, phosphoinositide binding, protein transport
• Biological source: Homo sapiens (human)
• Cellular location: Membrane ; Multi-pass membrane protein : Q9Y5W7
• Total number of polymer chains: 1
• Total formula weight: 15227.16

Authors

Mas, C.,Norwood, S.,Bugarcic, A.,Kinna, G.,Leneva, N.,Kovtun, O.,Teasdale, R.,Collins, B. (deposition date: 2014-03-03, release date: 2014-09-03, Last modification date: 2024-02-28)

• Primary citation: Mas, C.,Norwood, S.J.,Bugarcic, A.,Kinna, G.,Leneva, N.,Kovtun, O.,Ghai, R.,Ona Yanez, L.E.,Davis, J.L.,Teasdale, R.D.,Collins, B.M.; Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.; J.Biol.Chem., 289:28554-28568, 2014; PubMed: 25148684; DOI: 10.1074/jbc.M114.595959

Experimental method

X-RAY DIFFRACTION (2.55 Å)