5B16

X-ray structure of DROSHA in complex with the C-terminal tail of DGCR8.

Summary for 5B16

• Entry DOI: 10.2210/pdb5b16/pdb
• Descriptor: Ribonuclease 3,DROSHA,Ribonuclease 3,DROSHA,Ribonuclease 3, Microprocessor complex subunit DGCR8, ZINC ION (3 entities in total)
• Functional Keywords: endonuclease, rnase iii, trimeric complex, zinc finger, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : Q9NRR4 Q8WYQ5
• Total number of polymer chains: 3
• Total formula weight: 118000.68

Authors

Kwon, S.C.,Nguyen, T.A.,Choi, Y.G.,Jo, M.H.,Hohng, S.,Kim, V.N.,Woo, J.S. (deposition date: 2015-11-23, release date: 2016-02-03)

• Primary citation: Kwon, S.C.,Nguyen, T.A.,Choi, Y.G.,Jo, M.H.,Hohng, S.,Kim, V.N.,Woo, J.S.; Structure of Human DROSHA; Cell, 164:81-90, 2016; PubMed: 26748718; DOI: 10.1016/j.cell.2015.12.019

Experimental method

X-RAY DIFFRACTION (3.2 Å)