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5B16
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BU of 5b16 by Molmil
X-ray structure of DROSHA in complex with the C-terminal tail of DGCR8.
Descriptor: Microprocessor complex subunit DGCR8, Ribonuclease 3,DROSHA,Ribonuclease 3,DROSHA,Ribonuclease 3, ZINC ION
Authors:Kwon, S.C, Nguyen, T.A, Choi, Y.G, Jo, M.H, Hohng, S, Kim, V.N, Woo, J.S.
Deposit date:2015-11-23
Release date:2016-02-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Human DROSHA
Cell, 164, 2016
7CNC
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BU of 7cnc by Molmil
cystal structure of human ERH in complex with DGCR8
Descriptor: Enhancer of rudimentary homolog, Microprocessor complex subunit DGCR8
Authors:Li, F, Shen, S.
Deposit date:2020-07-30
Release date:2020-10-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:ERH facilitates microRNA maturation through the interaction with the N-terminus of DGCR8.
Nucleic Acids Res., 48, 2020
2QI2
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BU of 2qi2 by Molmil
Crystal structure of the Thermoplasma acidophilum Pelota protein
Descriptor: Cell division protein pelota related protein
Authors:Lee, H.H, Kim, Y.S, Kim, K.H, Heo, I.H, Kim, S.K, Kim, O, Suh, S.W.
Deposit date:2007-07-03
Release date:2007-10-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional insights into dom34, a key component of no-go mRNA decay
Mol.Cell, 27, 2007
7XW2
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BU of 7xw2 by Molmil
Cryo-EM structure of human DICER-pre-miRNA in a dicing state
Descriptor: CALCIUM ION, Endoribonuclease Dicer, RNA (73-MER)
Authors:Lee, H, Roh, S.-H.
Deposit date:2022-05-26
Release date:2023-03-08
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structure of the human DICER-pre-miRNA complex in a dicing state.
Nature, 615, 2023
7XW3
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BU of 7xw3 by Molmil
Cryo-EM structure of an apo-form of human DICER
Descriptor: Endoribonuclease Dicer
Authors:Lee, H, Roh, S.-H.
Deposit date:2022-05-26
Release date:2023-03-08
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Structure of the human DICER-pre-miRNA complex in a dicing state.
Nature, 615, 2023
2YT4
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BU of 2yt4 by Molmil
Crystal structure of human DGCR8 core
Descriptor: Protein DGCR8
Authors:Cho, Y, Sohn, S.Y.
Deposit date:2007-04-05
Release date:2007-08-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human DGCR8 core
Nat.Struct.Mol.Biol., 14, 2007
4NGD
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BU of 4ngd by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having 5'-p and UU-3' ends (1.95 Angstrom resolution)
Descriptor: 5'-R(P*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', DI(HYDROXYETHYL)ETHER, Endoribonuclease Dicer, ...
Authors:Tian, Y, Simanshu, D.K, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.958 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NHA
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BU of 4nha by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 16-mer siRNA having 5'-p and UU-3' ends (3.4 Angstrom resolution)
Descriptor: 5'-R(P*GP*CP*GP*UP*UP*GP*GP*CP*CP*AP*AP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Ma, J.-B, Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.401 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NH5
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BU of 4nh5 by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 14-mer siRNA having 5'-pUU and UU-3' ends (2.55 Angstrom resolution)
Descriptor: 5'-R(P*UP*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
Authors:Tian, Y, Simanshu, D.K, Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGG
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BU of 4ngg by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 13-mer siRNA having 5'-A and UU-3' ends (2.6 Angstrom resolution)
Descriptor: 5'-R(*AP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer, PHOSPHATE ION
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGC
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BU of 4ngc by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having UA-3' ends (2.1 Angstrom resolution)
Descriptor: 5'-R(*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*A)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NH6
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BU of 4nh6 by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 15-mer siRNA having 5'-pUUU and UU-3' ends (2.55 Angstrom resolution)
Descriptor: 5'-R(P*UP*UP*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.551 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGF
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BU of 4ngf by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 17-mer siRNA having 5'-p and UU-3' ends (3.1 Angstrom resolution)
Descriptor: 5'-R(P*UP*CP*GP*AP*AP*GP*GP*UP*CP*CP*UP*UP*CP*GP*UP*UP*U)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NGB
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BU of 4ngb by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having UU-3' ends (2.25 Angstrom resolution)
Descriptor: 5'-R(*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-01
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014
4NH3
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BU of 4nh3 by Molmil
Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 13-mer siRNA having 5'-pU and UU-3' ends (2.6 Angstrom resolution)
Descriptor: 5'-R(P*UP*GP*CP*GP*AP*AP*UP*UP*CP*GP*CP*UP*U)-3', Endoribonuclease Dicer
Authors:Simanshu, D.K, Tian, Y, Patel, D.J.
Deposit date:2013-11-04
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.616 Å)
Cite:A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
Mol.Cell, 53, 2014

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