2BCJ

Crystal Structure of G Protein-Coupled Receptor Kinase 2 in Complex with Galpha-q and Gbetagamma Subunits

2BCJ の概要

• エントリーDOI: 10.2210/pdb2bcj/pdb
• 関連するPDBエントリー: 1OMW 1YM7
• 分子名称: G-protein-coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total)
• 機能のキーワード: peripheral membrane complex, protein kinase, rgs domain, wd40 protein, heterotrimeric g protein, transferase-hydrolase complex, transferase/hydrolase
• 由来する生物種: Bos taurus (Bovine); 詳細
• 細胞内の位置: Cytoplasm : P21146; Cell membrane ; Lipid-anchor ; Cytoplasmic side : P63212; Nucleus : P21279
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 166776.15

構造登録者

Tesmer, J.J.G. (登録日: 2005-10-19, 公開日: 2005-12-20, 最終更新日: 2023-08-23)

• 主引用文献: Tesmer, V.M.,Kawano, T.,Shankaranarayanan, A.,Kozasa, T.,Tesmer, J.J.G.; Snapshot of Activated G Proteins at the Membrane: The Gq-GRK2-G Complex; Science, 310:1686-1690, 2005; PubMed: 16339447; DOI: 10.1126/science.1118890

実験手法

X-RAY DIFFRACTION (3.061 Å)