1C15
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SOLUTION STRUCTURE OF APAF-1 CARD
Descriptor:APAF-1 CARD
Authors:Zhou, P., Chou, J., Olea, R.S., Yuan, J., Wagner, G.
Deposit date:1999-07-20
Release date:1999-09-20
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: a structural basis for specific adaptor/caspase interaction.
Proc.Natl.Acad.Sci.USA, 96, 1999
1CWW
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SOLUTION STRUCTURE OF THE CASPASE RECRUITMENT DOMAIN (CARD) FROM APAF-1
Descriptor:APOPTOTIC PROTEASE ACTIVATING FACTOR 1
Authors:Day, C.L., Dupont, C., Lackmann, M., Vaux, D.L., Hinds, M.G.
Deposit date:1999-08-26
Release date:2000-01-21
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1.
Cell Death Differ., 6, 1999
1CY5
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CRYSTAL STRUCTURE OF THE APAF-1 CARD
Descriptor:PROTEIN (APOPTOTIC PROTEASE ACTIVATING FACTOR 1)
Authors:Vaughn, D.E., Joshua-Tor, L.
Deposit date:1999-08-31
Release date:1999-09-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling.
J.Mol.Biol., 293, 1999
1DGN
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SOLUTION STRUCTURE OF ICEBERG, AN INHIBITOR OF INTERLEUKIN-1BETA GENERATION
Descriptor:ICEBERG
Authors:Humke, E.W., Shriver, S.K., Starovasnik, M.A., Fairbrother, W.J., Dixit, V.M.
Deposit date:1999-11-24
Release date:2000-10-09
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:ICEBERG: a novel inhibitor of interleukin-1beta generation.
Cell(Cambridge,Mass.), 103, 2000
2B1W
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SOLUTION STRUCTURE OF THE NOD1 CASPASE ACTIVATING AND RECRUITMENT DOMAIN
Descriptor:Caspase recruitment domain protein 4
Authors:Manon, F., Favier, A., Simorre, J.P., Cusack, S.
Deposit date:2005-09-16
Release date:2006-09-26
Modification date:2011-10-05
Method:SOLUTION NMR
Cite:Solution structure of NOD1 CARD and mutational analysis of its interaction with the CARD of downstream kinase RICK.
J.Mol.Biol., 365, 2007
2DBD
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SOLUTION STRUCTURE OF THE CARD DOMAIN IN HUMAN CASPASE RECRUITMENT DOMAIN PROTEIN 4 (NOD1 PROTEIN)
Descriptor:Caspase recruitment domain protein 4
Authors:Saito, K., Inoue, M., Koshiba, S., Kigawa, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-15
Release date:2006-12-19
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the CARD domain in human caspase recruitment domain protein 4 (Nod1 protein)
To be Published
2L9M
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STRUCTURE OF CIAP1 CARD
Descriptor:Baculoviral IAP repeat-containing protein 2
Authors:Day, C.L., Rautureau, G.J.P., Hinds, M.G.
Deposit date:2011-02-21
Release date:2011-08-17
Method:SOLUTION NMR
Cite:CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration.
Mol.Cell, 42, 2011
2MB9
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HUMAN BCL10 CARD
Descriptor:B-cell lymphoma/leukemia 10
Authors:Zheng, C., Bracken, C., Wu, H.
Deposit date:2013-07-26
Release date:2013-10-16
Method:SOLUTION NMR
Cite:Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly.
Mol.Cell, 51, 2013
2N7Z
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SOLUTION STRUCTURE OF RIP2 CARD
Descriptor:Receptor-interacting serine/threonine-protein kinase 2 (E.C.2.7.11.1, 2.7.10.2)
Authors:Lin, Z., Ibanez, C.F.
Deposit date:2015-09-28
Release date:2015-12-23
Modification date:2016-01-13
Method:SOLUTION NMR
Cite:Structural basis of death domain signaling in the p75 neurotrophin receptor
Elife, 4, 2015
2NSN
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CRYSTAL STRUCTURE OF CASPACE ACTIVATION AND RECRUITMENT DOMAIN (CARD) OF NOD1
Descriptor:Caspase recruitment domain-containing protein 4
Authors:Ramaswamy, S., Coussens, N.P.
Deposit date:2006-11-05
Release date:2006-12-19
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the Nod1 caspase activation and recruitment domain.
Biochem.Biophys.Res.Commun., 353, 2007
2NZ7
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CRYSTAL STRUCTURE ANALYSIS OF CASPASE-RECRUITMENT DOMAIN (CARD) OF NOD1
Descriptor:Caspase recruitment domain-containing protein 4
Authors:Thiagarajan, S., Robbins, S.L., Dubas, R.L., Park, Y.C.
Deposit date:2006-11-22
Release date:2007-12-04
Modification date:2008-12-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Monomer/dimer transition of the caspase-recruitment domain of human Nod1
Biochemistry, 47, 2008
2P1H
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RAPID FOLDING AND UNFOLDING OF APAF-1 CARD
Descriptor:Apoptotic protease-activating factor 1
Authors:Milam, S.L., Nicely, N.I., Feeney, B., Mattos, C., Clark, A.C.
Deposit date:2007-03-05
Release date:2007-05-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Rapid Folding and Unfolding of Apaf-1 CARD.
J.Mol.Biol., 369, 2007
2YGS
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CARD DOMAIN FROM APAF-1
Descriptor:APOPTOTIC PROTEASE ACTIVATING FACTOR 1
Authors:Shi, Y.
Deposit date:1999-05-08
Release date:2000-04-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.
Nature, 399, 1999
3CRD
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NMR STRUCTURE OF THE RAIDD CARD DOMAIN, 15 STRUCTURES
Descriptor:RAIDD
Authors:Chou, J.J., Matsuo, H., Duan, H., Wagner, G.
Deposit date:1998-07-24
Release date:1999-02-02
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment.
Cell(Cambridge,Mass.), 94, 1998
3KAT
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CRYSTAL STRUCTURE OF THE CARD DOMAIN OF THE HUMAN NLRP1 PROTEIN, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR3486E
Descriptor:NACHT, LRR and PYD domains-containing protein 1
Authors:Forouhar,F., Abashidze, M., Seetharaman, J., Mao,M., Xiao,R., Ciccosanti,C., Shastry,R., Everett, J.K., Nair, R., Acton, T.B., Rost, B., Montelione, G.T., Tong,L., Hunt,J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-10-19
Release date:2009-10-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Northeast Structural Genomics Consortium Target HR3486E
To be Published
4E9M
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NOD1 CARD DOMAIN WITH THREE DISULFIDE-CLINCHED, DOMAIN-SWAPPED DIMERS IN THE ASYMMETRIC UNIT
Descriptor:Nucleotide-binding oligomerization domain-containing protein 1
Authors:Berry, E.A., Huang, L.S., Walker-Kopp, N.
Deposit date:2012-03-21
Release date:2012-04-04
Modification date:2013-02-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of nod1 card domain with three disulfide-clinched, domain-swapped dimers in the asymmetric unit
To be Published
4I16
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CRYSTAL STRUCTURE OF CARMA1 CARD
Descriptor:Caspase recruitment domain-containing protein 11
Authors:Li, S., Yang, X., Shen, Y.
Deposit date:2012-11-20
Release date:2012-12-26
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Structural insights into the assembly of CARMA1 and BCL10
Plos One, 7, 2012
4JUP
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DIMERIC STRUCTURE OF CARMA1 CARD
Descriptor:Caspase recruitment domain-containing protein 11
Authors:Park, H.H.
Deposit date:2013-03-25
Release date:2014-02-05
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Novel Disulfide Bond-Mediated Dimerization of the CARD Domain Was Revealed by the Crystal Structure of CARMA1 CARD
Plos One, 8, 2013
4LWD
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HUMAN CARMA1 CARD DOMAIN
Descriptor:Caspase recruitment domain-containing protein 11
Authors:Zheng, C., Wu, H.
Deposit date:2013-07-26
Release date:2013-10-16
Method:X-RAY DIFFRACTION (1.792 Å)
Cite:Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly.
Mol.Cell, 51, 2013
4UZ0
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CRYSTAL STRUCTURE OF APOPTOSIS REPRESSOR WITH CARD (ARC)
Descriptor:NUCLEOLAR PROTEIN 3
Authors:Kim, S.H., Jeong, J.H., Jang, T.H., Kim, Y.G., Park, H.H.
Deposit date:2014-09-04
Release date:2015-07-01
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Crystal Structure of Caspase Recruiting Domain (Card) of Apoptosis Repressor with Card (Arc) and its Implication in Inhibition of Apoptosis.
Sci.Rep., 5, 2015
5FNA
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CRYO-EM RECONSTRUCTION OF CASPASE-1 CARD
Descriptor:CASPASE-1 (E.C.3.4.22.36)
Authors:Li, Y., Lu, A., Schmidt, F.I., Yin, Q., Chen, S., Fu, T.M., Tong, A.B., Ploegh, H.L., Mao, Y., Wu, H.
Deposit date:2015-11-11
Release date:2016-03-30
Modification date:2016-05-18
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular Basis of Caspase-1 Polymerization and its Inhibition by a Novel Capping Mechanism
Nat.Struct.Mol.Biol., 23, 2016
5H8O
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CRYSTAL STRUCTURE OF AN ASC-BINDING NANOBODY IN COMPLEX WITH THE CARD DOMAIN OF ASC
Descriptor:VHH nanobody, Apoptosis-associated speck-like protein containing a CARD
Authors:Lu, A., Schmidt, F.I., Ruan, J., Tang, C., Wu, H., Ploegh, H.L.
Deposit date:2015-12-23
Release date:2016-04-06
Modification date:2016-05-18
Method:X-RAY DIFFRACTION (4.206 Å)
Cite:A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly.
J.Exp.Med., 213, 2016
3YGS
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APAF-1 CARD IN COMPLEX WITH PRODOMAIN OF PROCASPASE-9
Descriptor:APOPTOTIC PROTEASE ACTIVATING FACTOR 1
Authors:Qin, H., Srinivasula, S., Wu, G., Fernandes-Alnemri, T., Alnemri, E., Shi, Y.
Deposit date:1999-05-08
Release date:2000-04-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.
Nature, 399, 1999
4RHW
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CRYSTAL STRUCTURE OF APAF-1 CARD AND CASPASE-9 CARD COMPLEX
Descriptor:Apoptotic protease-activating factor 1, Caspase-9 (E.C.3.4.22.62)
Authors:Hu, Q., Wu, D., Yan, C., Shi, Y.
Deposit date:2014-10-03
Release date:2014-10-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome
Proc.Natl.Acad.Sci.USA, 2014
1Z6T
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STRUCTURE OF THE APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 BOUND TO ADP
Descriptor:Apoptotic protease activating factor 1
Authors:Riedl, S.J., Li, W., Chao, Y., Schwarzenbacher, R., Shi, Y.
Deposit date:2005-03-23
Release date:2005-04-19
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure of the apoptotic protease-activating factor 1 bound to ADP
Nature, 434, 2005
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