1LS3
 
 | | Crystal Structure of the Complex between Rabbit Cytosolic Serine Hydroxymethyltransferase and TriGlu-5-formyl-tetrahydrofolate | | Descriptor: | 2-[4-(4-{4-[(2-AMINO-5-FORMYL-4-OXO-3,4,5,6,7,8-HEXAHYDRO-PTERIDIN-6-YLMETHYL)-AMINO]-BENZOYLAMINO}-4-CARBOXY-BUTYRYLAM INO)-4-CARBOXY-BUTYRYLAMINO]-PENTANEDIOIC ACID, GLYCEROL, GLYCINE, ... | | Authors: | Fu, T.F, Scarsdale, J.N, Kazanina, G, Schirch, V, Wright, H.T. | | Deposit date: | 2002-05-16 | | Release date: | 2003-02-04 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Location of the Pteroylpolyglutamate Binding Site on Rabbit Cytosolic Serine Hydroxymethyltransferase
J.Biol.Chem., 278, 2003
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5L08
 | | Cryo-EM structure of Casp-8 tDED filament | | Descriptor: | Caspase-8 | | Authors: | Fu, T.M, Li, Y, Lu, A, Wu, H. | | Deposit date: | 2016-07-26 | | Release date: | 2016-11-02 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol.Cell, 64, 2016
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5JQE
 | | Crystal structure of caspase8 tDED | | Descriptor: | Sugar ABC transporter substrate-binding protein,Caspase-8 chimera | | Authors: | Fu, T, Li, Y, Lu, A, Wu, H. | | Deposit date: | 2016-05-04 | | Release date: | 2016-10-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (3.157 Å) | | Cite: | Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol. Cell, 64, 2016
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3T0C
 | | Crystal structure of Streptococcus mutans MetE complexed with Zinc | | Descriptor: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, SULFATE ION, ZINC ION | | Authors: | Fu, T.M, Liang, Y.H, Su, X.D. | | Deposit date: | 2011-07-19 | | Release date: | 2011-08-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.187 Å) | | Cite: | Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model
J.Mol.Biol., 412, 2011
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3LE3
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3L7R
 | | crystal structure of MetE from streptococcus mutans | | Descriptor: | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, SULFATE ION, ZINC ION | | Authors: | Fu, T.M, Liang, Y.H, Su, X.D. | | Deposit date: | 2009-12-29 | | Release date: | 2011-01-12 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.397 Å) | | Cite: | Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model
J.Mol.Biol., 412, 2011
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3LFH
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3LFG
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3LFJ
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3LE5
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3LE1
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5ZAT
 | | Crystal structure of 5-carboxylcytosine containing decamer dsDNA | | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*(CAC)P*GP*CP*TP*GP*G)-3') | | Authors: | Fu, T.R, Zhang, L. | | Deposit date: | 2018-02-08 | | Release date: | 2019-02-13 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.06 Å) | | Cite: | Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
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5ZAS
 | | Crystal structure of 5-formylcytosine containing decamer dsDNA | | Descriptor: | BICARBONATE ION, DNA (5'-D(*CP*CP*AP*GP*(5FC)P*GP*CP*TP*GP*G)-3') | | Authors: | Fu, T.R, Zhang, L. | | Deposit date: | 2018-02-08 | | Release date: | 2019-02-13 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.
Chem Sci, 10, 2019
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7EA7
 | | crystal structure of NAP1 LIR in complex with GABARAP | | Descriptor: | Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif | | Authors: | Fu, T, Pan, L. | | Deposit date: | 2021-03-06 | | Release date: | 2021-12-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
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7EA2
 | | crystal structure of NAP1 FIR in complex with RB1CC1 Claw domain | | Descriptor: | 5-azacytidine-induced protein 2,RB1-inducible coiled-coil protein 1, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Fu, T, Pan, L. | | Deposit date: | 2021-03-06 | | Release date: | 2021-12-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
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7EAA
 | | crystal structure of NDP52 SKICH domain in complex with RB1CC1 coiled-coil domain | | Descriptor: | Calcium-binding and coiled-coil domain-containing protein 2, RB1-inducible coiled-coil protein 1 | | Authors: | Fu, T, Pan, L. | | Deposit date: | 2021-03-06 | | Release date: | 2021-12-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
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5Z7L
 | | Crystal structure of NDP52 SKICH region in complex with NAP1 | | Descriptor: | 5-azacytidine-induced protein 2, Calcium-binding and coiled-coil domain-containing protein 2, GLYCEROL | | Authors: | Fu, T, Pan, L.F. | | Deposit date: | 2018-01-29 | | Release date: | 2019-01-02 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8TJY
 | | Structure of Gabija AB complex | | Descriptor: | Endonuclease GajA, Gabija protein GajB | | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | | Deposit date: | 2023-07-24 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | Molecular basis of Gabija anti-phage supramolecular assemblies
Nat.Struct.Mol.Biol., 2024
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8TK0
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8TK1
 | | Structure of Gabija AB complex 1 | | Descriptor: | Endonuclease GajA, Gabija protein GajB | | Authors: | Shen, Z.F, Yang, X.Y, Fu, T.M. | | Deposit date: | 2023-07-25 | | Release date: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Molecular basis of Gabija anti-phage supramolecular assemblies
Nat.Struct.Mol.Biol., 2024
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6XKK
 | | Cryo-EM structure of the NLRP1-CARD filament | | Descriptor: | NACHT, LRR and PYD domains-containing protein 1 | | Authors: | Hollingsworth, L.R, David, L, Li, Y, Sharif, H, Fontana, P, Fu, T, Wu, H. | | Deposit date: | 2020-06-26 | | Release date: | 2020-11-25 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.72 Å) | | Cite: | Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes.
Nat Commun, 12, 2021
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8SU9
 | | E. coli SIR2-HerA complex (hexamer HerA bound with dodecamer Sir2) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside triphosphate hydrolase, ... | | Authors: | Shen, Z.F, Lin, Q.P, Fu, T.M. | | Deposit date: | 2023-05-11 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
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8SUW
 | | E. coli SIR2-HerA complex (dodecamer SIR2 bound 4 protomers of HerA) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside triphosphate hydrolase, ... | | Authors: | Shen, Z.F, Lin, Q.P, Fu, T.M. | | Deposit date: | 2023-05-13 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
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8UAE
 | | E. coli Sir2_HerA complex (12:6) with ATPgamaS | | Descriptor: | MAGNESIUM ION, Nucleoside triphosphate hydrolase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | Authors: | Shen, Z.F, Lin, Q.P, Fu, T.M. | | Deposit date: | 2023-09-20 | | Release date: | 2023-12-27 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
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8UAF
 | | E. coli Sir2_HerA complex (12:6) bound with NAD+ | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Shen, Z.F, Lin, Q.P, Fu, T.M. | | Deposit date: | 2023-09-20 | | Release date: | 2023-12-27 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense.
Mol.Cell, 83, 2023
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