5FNA
Cryo-EM reconstruction of caspase-1 CARD
Summary for 5FNA
Entry DOI | 10.2210/pdb5fna/pdb |
EMDB information | 3241 |
Descriptor | Caspase-1 (1 entity in total) |
Functional Keywords | hydrolase, card, inflammasome, filament, signalosome, helical reconstruction, death domain |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 76721.37 |
Authors | Li, Y.,Lu, A.,Schmidt, F.I.,Yin, Q.,Chen, S.,Fu, T.M.,Tong, A.B.,Ploegh, H.L.,Mao, Y.,Wu, H. (deposition date: 2015-11-11, release date: 2016-03-30, Last modification date: 2019-09-11) |
Primary citation | Li, Y.,Lu, A.,Schmidt, F.I.,Yin, Q.,Chen, S.,Fu, T.M.,Tong, A.B.,Ploegh, H.L.,Mao, Y.,Wu, H. Molecular Basis of Caspase-1 Polymerization and its Inhibition by a Novel Capping Mechanism Nat.Struct.Mol.Biol., 23:416-, 2016 Cited by PubMed: 27043298DOI: 10.1038/NSMB.3199 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.8 Å) |
Structure validation
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