5WVC

Structure of the CARD-CARD disk

Summary for 5WVC

• Entry DOI: 10.2210/pdb5wvc/pdb
• Descriptor: Apoptotic protease-activating factor 1, Caspase, IODIDE ION (3 entities in total)
• Functional Keywords: protein-protein interaction, signaling protein complex, apoptosis
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm : O14727
• Total number of polymer chains: 6
• Total formula weight: 86402.56

Authors

Lin, S.C.,Lo, Y.C.,Su, T.W. (deposition date: 2016-12-24, release date: 2017-04-19)

• Primary citation: Su, T.W.,Yang, C.Y.,Kao, W.P.,Kuo, B.J.,Lin, S.M.,Lin, J.Y.,Lo, Y.C.,Lin, S.C.; Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome.; Structure, 25:407-420, 2017; PubMed: 28111022; DOI: 10.1016/j.str.2016.12.019

Experimental method

X-RAY DIFFRACTION (2.993 Å)