1DGN

SOLUTION STRUCTURE OF ICEBERG, AN INHIBITOR OF INTERLEUKIN-1BETA GENERATION

Summary for 1DGN

Entry DOI	10.2210/pdb1dgn/pdb
Descriptor	ICEBERG (PROTEASE INHIBITOR) (1 entity in total)
Functional Keywords	antiparallel six-helix bundle, greek-key, hydrolase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	10023.68
Authors	Humke, E.W.,Shriver, S.K.,Starovasnik, M.A.,Fairbrother, W.J.,Dixit, V.M. (deposition date: 1999-11-24, release date: 2000-10-09, Last modification date: 2022-02-16)
Primary citation	Humke, E.W.,Shriver, S.K.,Starovasnik, M.A.,Fairbrother, W.J.,Dixit, V.M. ICEBERG: a novel inhibitor of interleukin-1beta generation. Cell(Cambridge,Mass.), 103:99-111, 2000 Cited by PubMed: 11051551 DOI: 10.1016/S0092-8674(00)00108-2 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation