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2AEH
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2aeh
FOCAL ADHESION KINASE 1
Descriptor:Focal adhesion kinase 1 (E.C.2.7.1.112)
Authors:Ceccarelli, D.F., Song, H.K., Poy, F., Schaller, M.D., Eck, M.J.
Deposit date:2005-07-22
Release date:2005-10-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
2AL6
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2al6
FERM DOMAIN OF FOCAL ADHESION KINASE
Descriptor:Focal adhesion kinase 1 (E.C.2.7.1.112)
Authors:Ceccarelli, D.F., Song, H.K., Poy, F., Schaller, M.D., Eck, M.J.
Deposit date:2005-08-04
Release date:2005-10-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
2MSU
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2msu
NMR STRUCTURE OF KINDLIN-2 F2 339-358
Descriptor:Fermitin family homolog 2
Authors:Fukuda, K., Bledzka, K., Yang, J., Perera, H.D.
Deposit date:2014-08-05
Release date:2014-08-27
Modification date:2014-10-29
Method:SOLUTION NMR
Cite:Molecular Basis of Kindlin-2 Binding to Integrin-linked Kinase Pseudokinase for Regulating Cell Adhesion.
J.Biol.Chem., 289, 2014
2RQ1
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2rq1
SOLUTION STRUCTURE OF THE 4.1R FERM ALPHA LOBE DOMAIN
Descriptor:Protein 4.1
Authors:Kusunoki, H., Kohno, T.
Deposit date:2009-01-09
Release date:2009-04-14
Modification date:2009-05-19
Method:SOLUTION NMR
Cite:Solution structure and glycophorin C binding studies of the protein 4.1R FERM alpha-lobe domain
Proteins, 76, 2009
3U7D
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3u7d
CRYSTAL STRUCTURE OF THE KRIT1/CCM1 FERM DOMAIN IN COMPLEX WITH THE HEART OF GLASS (HEG1) CYTOPLASMIC TAIL
Descriptor:Krev interaction trapped protein 1, Protein HEG homolog 1
Authors:Gingras, A.R., Liu, J.J., Ginsberg, M.H., Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions (CELLMAT)
Deposit date:2011-10-13
Release date:2012-09-12
Modification date:2013-02-27
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.
J.Cell Biol., 199, 2012
3ZDT
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3zdt
CRYSTAL STRUCTURE OF BASIC PATCH MUTANT FAK FERM DOMAIN FAK31- 405 K216A, K218A, R221A, K222A
Descriptor:FOCAL ADHESION KINASE 1 (E.C.2.7.10.2)
Authors:Goni, G.M., Epifano, C., Boskovic, J., Camacho-Artacho, M., Zhou, J., Martin, M.T., Eck, M.J., Kremer, L., Graeter, F., Gervasio, F.L., Perez-Moreno, M., Lietha, D.
Deposit date:2012-11-30
Release date:2012-12-12
Modification date:2014-08-20
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Proc.Natl.Acad.Sci.USA, 111, 2014
4CYE
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4cye
CRYSTAL STRUCTURE OF AVIAN FAK FERM DOMAIN FAK31-405 AT 3.2A
Descriptor:FOCAL ADHESION KINASE 1 (E.C.2.7.10.2)
Authors:Goni, G.M., Epifano, C., Boskovic, J., Camacho-Artacho, M., Zhou, J., Martin, M.T., Eck, M.J., Kremer, L., Graeter, F., Gervasio, F.L., Perez-Moreno, M., Lietha, D.
Deposit date:2014-04-10
Release date:2014-04-23
Modification date:2014-08-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Proc.Natl.Acad.Sci.USA, 111, 2014
4EKU
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4eku
CRYSTAL STRUCTURE OF FERM DOMAIN OF PROLINE-RICH TYROSINE KINASE 2
Descriptor:Protein-tyrosine kinase 2-beta (E.C.2.7.10.2)
Authors:Savarimuthu, B., Li, R., Wang, Y.
Deposit date:2012-04-09
Release date:2012-04-25
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal Structure of the Ferm Domain of Proline-rich Tyrosine Kinase 2
To be Published
4NY0
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4ny0
CRYSTAL STRUCTURE OF FERM DOMAIN OF HUMAN FOCAL ADHESION KINASE
Descriptor:Focal adhesion kinase 1 (E.C.2.7.10.2)
Authors:Walkiewicz, K., Arold, S.T.
Deposit date:2013-12-10
Release date:2014-03-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:FAK dimerization controls its kinase-dependent functions at focal adhesions.
Embo J., 33, 2014
1E5W
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1e5w
STRUCTURE OF ISOLATED FERM DOMAIN AND FIRST LONG HELIX OF MOESIN
Descriptor:MOESIN
Authors:Edwards, S.D., Keep, N.H.
Deposit date:2000-08-03
Release date:2001-06-27
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The 2.7 Crystal Structure of the Activated Ferm Domain of Moesin: An Analysis of Structural Changes on Activation
Biochemistry, 40, 2001
1EF1
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1ef1
CRYSTAL STRUCTURE OF THE MOESIN FERM DOMAIN/TAIL DOMAIN COMPLEX
Descriptor:CRYSTAL STRUCTURE OF THE MOESIN FERM DOMAIN/TAIL DOMAIN COMPLEX
Authors:Pearson, M.A., Reczek, D., Bretscher, A., Karplus, P.A.
Deposit date:2000-02-04
Release date:2000-05-10
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain.
Cell(Cambridge,Mass.), 101, 2000
1GC6
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1gc6
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE
Descriptor:THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE
Authors:Hamada, K., Shimizu, T., Matsui, T., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GC7
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1gc7
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN
Descriptor:THE RADIXIN FERM DOMAIN
Authors:Hamada, K., Shimizu, T., Matsui, T., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GG3
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1gg3
CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN
Descriptor:ERYTHROID MEMBRANE PROTEIN 4.1
Authors:Han, B.G.
Deposit date:2000-07-11
Release date:2001-01-10
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Nat.Struct.Biol., 7, 2000
1H4R
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1h4r
CRYSTAL STRUCTURE OF THE FERM DOMAIN OF MERLIN, THE NEUROFIBROMATOSIS 2 TUMOR SUPPRESSOR PROTEIN.
Descriptor:MERLIN
Authors:Cooper, D.R., Kang, B.S., Sheffield, P., Devedjiev, Y., Derewenda, Z.S.
Deposit date:2001-05-14
Release date:2002-01-16
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product.
Acta Crystallogr.,Sect.D, 58, 2002
1ISN
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1isn
CRYSTAL STRUCTURE OF MERLIN FERM DOMAIN
Descriptor:merlin
Authors:Shimizu, T., Seto, A., Maita, N., Hamada, K., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2001-12-13
Release date:2002-04-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
J.Biol.Chem., 277, 2002
1J19
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1j19
CRYSTAL STRUCTURE OF THE RADXIN FERM DOMAIN COMPLEXED WITH THE ICAM-2 CYTOPLASMIC PEPTIDE
Descriptor:radixin/16-mer peptide from Intercellular adhesion molecule-2
Authors:Hamada, K., Shimizu, T., Yonemura, S., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2002-12-02
Release date:2003-03-11
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex
EMBO J., 22, 2003
1MIX
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1mix
CRYSTAL STRUCTURE OF A FERM DOMAIN OF TALIN
Descriptor:Talin
Authors:Garcia-Alvarez, B., de Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1NI2
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1ni2
STRUCTURE OF THE ACTIVE FERM DOMAIN OF EZRIN
Descriptor:Ezrin
Authors:Smith, W.J., Nassar, N., Bretscher, A.P., Cerione, R.A., Karplus, P.A.
Deposit date:2002-12-20
Release date:2003-02-25
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Active N-terminal Domain of Ezrin. CONFORMATIONAL AND MOBILITY CHANGES IDENTIFY KEYSTONE INTERACTIONS.
J.Biol.Chem., 278, 2003
1SGH
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1sgh
MOESIN FERM DOMAIN BOUND TO EBP50 C-TERMINAL PEPTIDE
Descriptor:Moesin, Ezrin-radixin-moesin binding phosphoprotein 50
Authors:Finnerty, C.M., Chambers, D., Ingraffea, J., Faber, H.R., Karplus, P.A., Bretscher, A.
Deposit date:2004-02-23
Release date:2004-06-29
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain
J.Cell.Sci., 117, 2004
1Y19
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1y19
STRUCTURAL BASIS FOR PHOSPHATIDYLINOSITOL PHOSPHATE KINASE TYPE I-GAMMA BINDING TO TALIN AT FOCAL ADHESIONS
Descriptor:Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1
Authors:de Pereda, J.M., Wegener, K., Santelli, E., Bate, N., Ginsberg, M.H., Critchley, D.R., Campbell, I.D., Liddington, R.C.
Deposit date:2004-11-17
Release date:2005-01-04
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions
J.Biol.Chem., 280, 2005
2D10
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2d10
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH THE NHERF-1 C-TERMINAL TAIL PEPTIDE
Descriptor:Radixin, Ezrin-radixin-moesin binding phosphoprotein 50
Authors:Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D11
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2d11
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH THE NHERF-2 C-TERMINAL TAIL PEPTIDE
Descriptor:Radixin, Na(+)/H(+) exchange regulatory cofactor NHE-RF2
Authors:Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D2Q
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2d2q
CRYSTAL STRUCTURE OF THE DIMERIZED RADIXIN FERM DOMAIN
Descriptor:Radixin
Authors:Kitano, K., Yusa, F., Hakoshima, T.
Deposit date:2005-09-15
Release date:2006-04-18
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2EMS
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2ems
CRYSTAL STRUCTURE ANALYSIS OF THE RADIXIN FERM DOMAIN COMPLEXED WITH ADHESION MOLECULE CD43
Descriptor:Radixin, Leukosialin
Authors:Takai, Y., Kitano, K., Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2007-03-28
Release date:2008-04-01
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins
J.Mol.Biol., 381, 2008
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entries available on 2014-12-17
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