3G9W

Crystal Structure of Talin2 F2-F3 in Complex with the Integrin Beta1D Cytoplasmic Tail

Summary for 3G9W

• Entry DOI: 10.2210/pdb3g9w/pdb
• Descriptor: Talin-2, Integrin beta-1D, GLYCEROL, ... (5 entities in total)
• Functional Keywords: protein-protein complex, ph domain superfold, ptb domain, helical bundle, intrinsically unstructured, cell adhesion
• Biological source: Mus musculus (mouse); More
• Cellular location: Cell junction, focal adhesion (By similarity): Q71LX4; Cell membrane; Single-pass type I membrane protein. Isoform 5: Cell membrane, sarcolemma (By similarity): P05556
• Total number of polymer chains: 4
• Total formula weight: 64670.16

Authors

Anthis, N.J.,Wegener, K.L.,Ye, F.,Kim, C.,Lowe, E.D.,Vakonakis, I.,Bate, N.,Critchley, D.R.,Ginsberg, M.H.,Campbell, I.D. (deposition date: 2009-02-15, release date: 2009-10-20, Last modification date: 2023-11-01)

• Primary citation: Anthis, N.J.,Wegener, K.L.,Ye, F.,Kim, C.,Goult, B.T.,Lowe, E.D.,Vakonakis, I.,Bate, N.,Critchley, D.R.,Ginsberg, M.H.,Campbell, I.D.; The structure of an integrin/talin complex reveals the basis of inside-out signal transduction; Embo J., 28:3623-3632, 2009; PubMed: 19798053; DOI: 10.1038/emboj.2009.287

Experimental method

X-RAY DIFFRACTION (2.165 Å)