1Y19

Structural basis for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions

Summary for 1Y19

Entry DOI	10.2210/pdb1y19/pdb
Related	1MIX 1MIZ 1MK7 1MK9
Descriptor	Phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma, Talin 1 (3 entities in total)
Functional Keywords	focal adhesion; ferm domain; cytoskeleton; npxy motif; ptb domain, structural protein, signaling protein
Biological source	Mus musculus (house mouse) More
Cellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side: O70161 Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side : P26039
Total number of polymer chains	12
Total formula weight	149962.76
Authors	de Pereda, J.M.,Wegener, K.,Santelli, E.,Bate, N.,Ginsberg, M.H.,Critchley, D.R.,Campbell, I.D.,Liddington, R.C. (deposition date: 2004-11-17, release date: 2005-01-04, Last modification date: 2016-11-30)
Primary citation	de Pereda, J.M.,Wegener, K.,Santelli, E.,Bate, N.,Ginsberg, M.H.,Critchley, D.R.,Campbell, I.D.,Liddington, R.C. Structural bases for phosphatidylinositol phosphate kinase type I-gamma binding to talin at focal adhesions J.Biol.Chem., 280:8381-8386, 2005 Cited by PubMed: 15623515 DOI: 10.1074/jbc.M413180200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation