8IBV
| Cryo-EM structure of the motilin-bound motilin receptor-Gq protein complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | 著者 | Jiang, Y, Xu, H.E, You, C, Xu, Y. | 登録日 | 2023-02-10 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structural basis for motilin and erythromycin recognition by motilin receptor. Sci Adv, 9, 2023
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7W2Z
| Cryo-EM structure of the ghrelin-bound human ghrelin receptor-Go complex | 分子名称: | Appetite-regulating hormone, CHOLESTEROL, Growth hormone secretagogue receptor type 1, ... | 著者 | Qin, J, Ming, Q, Ji, S, Mao, C, Shen, D, Zhang, Y. | 登録日 | 2021-11-24 | 公開日 | 2022-01-19 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Molecular mechanism of agonism and inverse agonism in ghrelin receptor. Nat Commun, 13, 2022
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7NA7
| Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist | 分子名称: | Antibody fragment, CHOLESTEROL, Ghrelin-27, ... | 著者 | Liu, H, Sun, D, Sun, J, Zhang, C. | 登録日 | 2021-06-20 | 公開日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren Nat Commun, 12, 2021
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7F9Y
| ghrelin-bound ghrelin receptor in complex with Gq | 分子名称: | CHOLESTEROL, Engineered G-alpha-q subunit, Ghrelin-28, ... | 著者 | Wang, Y, Zhuang, Y, Xu, P, Xu, H.E, Jiang, Y. | 登録日 | 2021-07-05 | 公開日 | 2021-08-18 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor. Nat Commun, 12, 2021
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6H3E
| Receptor-bound Ghrelin conformation | 分子名称: | Appetite-regulating hormone, octan-1-amine | 著者 | Ferre, G, Damian, M, M'Kadmi, C, Saurel, O, Czaplicki, G, Demange, P, Marie, J, Fehrentz, J.A, Baneres, J.L, Milon, A. | 登録日 | 2018-07-18 | 公開日 | 2019-07-24 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and dynamics of G protein-coupled receptor-bound ghrelin reveal the critical role of the octanoyl chain. Proc.Natl.Acad.Sci.USA, 116, 2019
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1LBJ
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