5AVO
 
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3MTJ
 | | The Crystal Structure of a Homoserine Dehydrogenase from Thiobacillus denitrificans to 2.15A | | 分子名称: | Homoserine dehydrogenase, SULFATE ION | | 著者 | Stein, A.J, Cui, H, Chin, S, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-04-30 | | 公開日 | 2010-05-12 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The Crystal Structure of a Homoserine Dehydrogenase from Thiobacillus denitrificans to 2.15A
To be Published
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6DZS
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1TVE
 | | Homoserine Dehydrogenase in complex with 4-(4-hydroxy-3-isopropylphenylthio)-2-isopropylphenol | | 分子名称: | 4-(4-HYDROXY-3-ISOPROPYLPHENYLTHIO)-2-ISOPROPYLPHENOL, Homoserine dehydrogenase | | 著者 | Ejim, L, Mirza, I.A, Capone, C, Nazi, I, Jenkins, S, Chee, G.L, Berghuis, A.M, Wright, G.D. | | 登録日 | 2004-06-29 | | 公開日 | 2004-07-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | New phenolic inhibitors of yeast homoserine dehydrogenase
Bioorg.Med.Chem., 12, 2004
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1Q7G
 | | Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline | | 分子名称: | Homoserine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE-5-HYDROXY-4-OXONORVALINE, SODIUM ION | | 著者 | Jacques, S.L, Mirza, I.A, Ejim, L, Koteva, K, Hughes, D.W, Green, K, Kinach, R, Honek, J.F, Lai, H.K, Berghuis, A.M, Wright, G.D. | | 登録日 | 2003-08-18 | | 公開日 | 2003-10-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Enzyme assisted suicide: Molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase
Chem.Biol., 10, 2003
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5X9D
 | | Crystal structure of homoserine dehydrogenase in complex with L-cysteine and NAD | | 分子名称: | (2R)-3-[[(4S)-3-aminocarbonyl-1-[(2R,3R,4S,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-3,4-bis(oxidanyl)oxolan-2-yl]-4H-pyridin-4-yl]sulfanyl]-2-azanyl-propanoic acid, Homoserine dehydrogenase, L(+)-TARTARIC ACID | | 著者 | Goto, M, Ogata, K, Kaneko, R, Yoshimune, K. | | 登録日 | 2017-03-06 | | 公開日 | 2018-05-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Inhibition of homoserine dehydrogenase by formation of a cysteine-NAD covalent complex
Sci Rep, 8, 2018
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2EJW
 | | Homoserine Dehydrogenase from Thermus thermophilus HB8 | | 分子名称: | GLYCEROL, Homoserine dehydrogenase, MAGNESIUM ION, ... | | 著者 | Omi, R, Goto, M, Miyahara, I, Hirotsu, K. | | 登録日 | 2007-03-21 | | 公開日 | 2008-02-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of Homoserine Dehydrogenase from Thermus thermophilus HB8
To be Published
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1EBU
 | | HOMOSERINE DEHYDROGENASE COMPLEX WITH NAD ANALOGUE AND L-HOMOSERINE | | 分子名称: | 3-AMINOMETHYL-PYRIDINIUM-ADENINE-DINUCLEOTIDE, HOMOSERINE DEHYDROGENASE, L-HOMOSERINE, ... | | 著者 | DeLaBarre, B, Thompson, P.R, Wright, G.D, Berghuis, A.M. | | 登録日 | 2000-01-24 | | 公開日 | 2000-03-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.
Nat.Struct.Biol., 7, 2000
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3C8M
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1EBF
 | | HOMOSERINE DEHYDROGENASE FROM S. CEREVISIAE COMPLEX WITH NAD+ | | 分子名称: | HOMOSERINE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION | | 著者 | DeLaBarre, B, Thompson, P.R, Wright, G.D, Berghuis, A.M. | | 登録日 | 2000-01-24 | | 公開日 | 2000-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.
Nat.Struct.Biol., 7, 2000
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3ING
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3DO5
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3JSA
 | | Homoserine dehydrogenase from Thermoplasma volcanium complexed with NAD | | 分子名称: | Homoserine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | | 著者 | Osipiuk, J, Nocek, B, Hendricks, R, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2009-09-09 | | 公開日 | 2009-09-22 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | X-ray crystal structure of Homoserine dehydrogenase from Thermoplasma volcanium
To be Published
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4XB2
 | | Hyperthermophilic archaeal homoserine dehydrogenase mutant in complex with NADPH | | 分子名称: | 319aa long hypothetical homoserine dehydrogenase, L-HOMOSERINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Sakuraba, H, Inoue, S, Yoneda, K, Ohshima, T. | | 登録日 | 2014-12-16 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases.
Sci Rep, 5, 2015
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4XB1
 | | Hyperthermophilic archaeal homoserine dehydrogenase in complex with NADPH | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 319aa long hypothetical homoserine dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Sakuraba, H, Inoue, S, Yoneda, K, Ohshima, T. | | 登録日 | 2014-12-16 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of a Hyperthermophilic Archaeal Homoserine Dehydrogenase Suggest a Novel Cofactor Binding Mode for Oxidoreductases.
Sci Rep, 5, 2015
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7F4B
 | | The crystal structure of the immature apo-enzyme of homoserine dehydrogenase from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | | 分子名称: | MAGNESIUM ION, homoserine dehydrogenase | | 著者 | Kurihara, E, Kubota, T, Watanabe, K, Ogata, K, Kaneko, R, Oshima, T, Yoshimune, K, Goto, M. | | 登録日 | 2021-06-18 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase.
Commun Biol, 5, 2022
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7F4C
 | | The crystal structure of the immature holo-enzyme of homoserine dehydrogenase complexed with NADP and 1,4-butandiol from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | | 分子名称: | 1,4-BUTANEDIOL, Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Ogata, K, Kaneko, R, Kubota, T, Watanabe, K, Kurihara, E, Oshima, T, Yoshimune, K, Goto, M. | | 登録日 | 2021-06-18 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase.
Commun Biol, 5, 2022
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4YDR
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7M92
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5XDF
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6A0R
 | | Homoserine dehydrogenase from Thermus thermophilus HB8 unliganded form | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FORMIC ACID, GLYCEROL, ... | | 著者 | Akai, S, Ikushiro, H, Sawai, T, Yano, T, Kamiya, N, Miyahara, I. | | 登録日 | 2018-06-06 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | The crystal structure of homoserine dehydrogenase complexed with l-homoserine and NADPH in a closed form
J. Biochem., 165, 2019
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6A0S
 | | Homoserine dehydrogenase from Thermus thermophilus HB8 complexed with HSE and NADPH | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FORMIC ACID, GLYCEROL, ... | | 著者 | Akai, S, Ikushiro, H, Sawai, T, Yano, T, Kamiya, N, Miyahara, I. | | 登録日 | 2018-06-06 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The crystal structure of homoserine dehydrogenase complexed with l-homoserine and NADPH in a closed form
J. Biochem., 165, 2019
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6A0U
 | | Homoserine dehydrogenase K195A mutant from Thermus thermophilus HB8 complexed with HSE and NADP+ | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FORMIC ACID, GLYCEROL, ... | | 著者 | Akai, S, Ikushiro, H, Sawai, T, Yano, T, Kamiya, N, Miyahara, I. | | 登録日 | 2018-06-06 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | The crystal structure of homoserine dehydrogenase complexed with l-homoserine and NADPH in a closed form
J. Biochem., 165, 2019
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6A0T
 | | Homoserine dehydrogenase K99A mutant from Thermus thermophilus HB8 complexed with HSE and NADP+ | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, FORMIC ACID, GLYCEROL, ... | | 著者 | Akai, S, Ikushiro, H, Sawai, T, Yano, T, Kamiya, N, Miyahara, I. | | 登録日 | 2018-06-06 | | 公開日 | 2018-11-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | The crystal structure of homoserine dehydrogenase complexed with l-homoserine and NADPH in a closed form
J. Biochem., 165, 2019
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4PG4
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