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1TK7
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BU of 1tk7 by Molmil
NMR structure of WW domains (WW3-4) from Suppressor of Deltex
分子名称: CG4244-PB
著者Fedoroff, O.Y, Avis, J.M, Golovanov, A.P, Baron, M, Townson, S.A.
登録日2004-06-08
公開日2004-07-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure and dynamics of tandem WW domains in a negative regulator of notch signaling, Suppressor of deltex
J.Biol.Chem., 279, 2004
2RM0
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BU of 2rm0 by Molmil
FBP28WW2 domain in complex with a PPPLIPPPP peptide
分子名称: Formin-1, Transcription elongation regulator 1
著者Ramirez-Espain, X, Ruiz, L, Martin-Malpartida, P, Oschkinat, H, Macias, M.J.
登録日2007-09-06
公開日2007-11-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Characterization of a New Binding Motif and a Novel Binding Mode in Group 2 WW Domains
J.Mol.Biol., 373, 2007
4N7F
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BU of 4n7f by Molmil
Crystal structure of 3rd WW domain of human Nedd4-1
分子名称: E3 ubiquitin-protein ligase NEDD4
著者Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J.
登録日2013-10-15
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.102 Å)
主引用文献Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3).
J.Biol.Chem., 289, 2014
2RLY
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BU of 2rly by Molmil
FBP28WW2 domain in complex with PTPPPLPP peptide
分子名称: Formin-1, Transcription elongation regulator 1
著者Ramirez-Espain, X, Ruiz, L, Martin-Malpartida, P, Oschkinat, H, Macias, M.J.
登録日2007-09-03
公開日2007-11-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Characterization of a New Binding Motif and a Novel Binding Mode in Group 2 WW Domains
J.Mol.Biol., 373, 2007
6RSS
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BU of 6rss by Molmil
Solution structure of the fourth WW domain of WWP2 with GB1-tag
分子名称: NEDD4-like E3 ubiquitin-protein ligase WWP2
著者Wahl, L.C, Watt, J.E, Tolchard, J, Blumenschein, T.M.A, Chantry, A.
登録日2019-05-22
公開日2019-10-09
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Smad7 Binds Differently to Individual and Tandem WW3 and WW4 Domains of WWP2 Ubiquitin Ligase Isoforms.
Int J Mol Sci, 20, 2019
4N7H
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BU of 4n7h by Molmil
Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3
分子名称: Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE
著者Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J.
登録日2013-10-15
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3).
J.Biol.Chem., 289, 2014
4GWT
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BU of 4gwt by Molmil
Structure of racemic Pin1 WW domain cocrystallized with DL-malic acid
分子名称: (2S)-2-hydroxybutanedioic acid, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T.
登録日2012-09-03
公開日2013-10-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.
Acta Crystallogr.,Sect.D, 69, 2013
4GWV
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BU of 4gwv by Molmil
Structure of racemic Pin1 WW domain cocrystallized with tri-ammonium citrate
分子名称: CITRATE ANION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Mortenson, D.E, Yun, H.G, Gellman, S.H, Forest, K.T.
登録日2012-09-03
公開日2013-10-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Evidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domain.
Acta Crystallogr.,Sect.D, 69, 2013
5DWS
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BU of 5dws by Molmil
Crystal Structure of ITCH WW3 domain in complex with TXNIP peptide
分子名称: E3 ubiquitin-protein ligase Itchy homolog, UNKNOWN ATOM OR ION, txnip
著者Liu, Y, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-22
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of ITCH WW3 domain in complex with TXNIP peptide
to be published
5DZD
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BU of 5dzd by Molmil
Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide
分子名称: E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-09-25
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide
To be Published
5CQ2
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BU of 5cq2 by Molmil
Crystal Structure of tandem WW domains of ITCH in complex with TXNIP peptide
分子名称: E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-07-21
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP.
Biochem.J., 473, 2016
1O6W
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BU of 1o6w by Molmil
Solution Structure of the Prp40 WW Domain Pair of the Yeast Splicing Factor Prp40
分子名称: PRE-MRNA PROCESSING PROTEIN PRP40
著者Wiesner, S, Stier, G, Sattler, M, Macias, M.J.
登録日2002-10-16
公開日2002-12-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure and Ligand Recognition of the Ww Domain Pair of the Yeast Splicing Factor Prp40
J.Mol.Biol., 324, 2002
6SVH
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BU of 6svh by Molmil
Protein allostery of the WW domain at atomic resolution: FFpSPR bound structure
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Strotz, D, Orts, J, Friedmann, M, Guntert, P, Vogeli, B, Riek, R.
登録日2019-09-18
公開日2020-09-30
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Protein Allostery at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 59, 2020
1E0L
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BU of 1e0l by Molmil
FBP28WW domain from Mus musculus
分子名称: FORMIN BINDING PROTEIN
著者Macias, M.J, Gervais, V, Civera, C, Oschkinat, H.
登録日2000-03-30
公開日2000-04-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Analysis of Ww Domains and Design of a Ww Prototype
Nat.Struct.Biol., 7, 2000
6SVE
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BU of 6sve by Molmil
Protein allostery of the WW domain at atomic resolution: pCdc25C bound structure
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Strotz, D, Orts, J, Friedmann, M, Guntert, P, Vogeli, B, Riek, R.
登録日2019-09-18
公開日2020-10-07
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Protein Allostery at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 59, 2020
6SVC
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BU of 6svc by Molmil
Protein allostery of the WW domain at atomic resolution: apo structure
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Strotz, D, Orts, J, Friedmann, M, Guntert, P, Vogeli, B, Riek, R.
登録日2019-09-18
公開日2020-09-30
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Protein Allostery at Atomic Resolution.
Angew.Chem.Int.Ed.Engl., 59, 2020
5AHT
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BU of 5aht by Molmil
Third WW domain from the E3 ubiquitin-protein ligase NEDD4
分子名称: E3 UBIQUITIN-PROTEIN LIGASE NEDD4
著者Panwalkar, V, Lecher, J, Dingley, A.
登録日2015-02-09
公開日2016-01-27
最終更新日2024-01-31
実験手法SOLUTION NMR
主引用文献The Nedd4-1 Ww Domain Recognizes the Py Motif Peptide Through Coupled Folding and Binding Equilibria.
Biochemistry, 55, 2016
8PXX
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BU of 8pxx by Molmil
Structure of the WW domain tandem of PRPF40A in complex with SF1
分子名称: Pre-mRNA-processing factor 40 homolog A, Splicing factor 1
著者Martinez-Lumbreras, S, Sattler, M.
登録日2023-07-24
公開日2024-04-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Nat Commun, 15, 2024
8PXW
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BU of 8pxw by Molmil
Structure of the WW domain tandem of PRPF40A
分子名称: Pre-mRNA-processing factor 40 homolog A
著者Martinez-Lumbreras, S, Sattler, M.
登録日2023-07-24
公開日2024-04-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Intramolecular autoinhibition regulates the selectivity of PRPF40A tandem WW domains for proline-rich motifs.
Nat Commun, 15, 2024
5YDX
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BU of 5ydx by Molmil
NMR structure of YAP1-2 WW1 domain with LATS1 PPxY motif complex
分子名称: WW domain with PPxY motif
著者Fan, J.S, Sivaraman, J.
登録日2017-09-15
公開日2018-05-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.
Oncotarget, 9, 2018
5YDY
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BU of 5ydy by Molmil
NMR structure of YAP1-2 WW2 domain with LATS1 PPxY motif complex
分子名称: WW2 domain and PPxY motif complex
著者Fan, J.S, Sivaraman, J.
登録日2017-09-15
公開日2018-05-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.
Oncotarget, 9, 2018
7BQF
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BU of 7bqf by Molmil
Dimerization of SAV1 WW tandem
分子名称: 1,4-DIETHYLENE DIOXIDE, Protein salvador homolog 1
著者Lin, Z, Zhang, M.
登録日2020-03-24
公開日2020-09-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.70037615 Å)
主引用文献A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling.
Cell Rep, 32, 2020
7BQG
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BU of 7bqg by Molmil
Complex structure of SAV1 and Dendrin
分子名称: POTASSIUM ION, Protein salvador homolog 1,Dendrin
著者Lin, Z, Zhang, M.
登録日2020-03-24
公開日2020-09-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.55010867 Å)
主引用文献A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling.
Cell Rep, 32, 2020
2DK1
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BU of 2dk1 by Molmil
Solution structure of WW domain in WW domain binding protein 4 (WBP-4)
分子名称: WW domain-binding protein 4
著者He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-04-06
公開日2006-10-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of WW domain in WW domain binding protein 4 (WBP-4)
To be Published
2DJY
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BU of 2djy by Molmil
Solution structure of Smurf2 WW3 domain-Smad7 PY peptide complex
分子名称: Mothers against decapentaplegic homolog 7, Smad ubiquitination regulatory factor 2
著者Chong, P.A, Lin, H, Wrana, J.L, Forman-Kay, J.D.
登録日2006-04-06
公開日2006-05-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An Expanded WW Domain Recognition Motif Revealed by the Interaction between Smad7 and the E3 Ubiquitin Ligase Smurf2.
J.Biol.Chem., 281, 2006

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