5DZD

Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide

Replaces:  4ROI

Summary for 5DZD

• Entry DOI: 10.2210/pdb5dzd/pdb
• Descriptor: E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, ligase-protein binding complex, ligase/protein binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side : Q96J02; Cytoplasm : Q9H3M7
• Total number of polymer chains: 4
• Total formula weight: 13725.48

Authors

Liu, Y.,Tempel, W.,Dong, A.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2015-09-25, release date: 2015-10-14, Last modification date: 2023-09-27)

• Primary citation: Liu, Y.,Tempel, W.,Dong, A.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.; Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide; To be Published,

Experimental method

X-RAY DIFFRACTION (1.57 Å)