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1B6U
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CRYSTAL STRUCTURE OF THE HUMAN KILLER CELL INHIBITORY RECEPTOR (KIR2DL3) SPECIFIC FOR HLA-CW3 RELATED ALLELES
分子名称: P58 KILLER CELL INHIBITORY RECEPTOR
著者Maenaka, K, Juji, T, Stuart, D.I, Jones, E.Y.
登録日1999-01-18
公開日1999-01-27
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the human p58 killer cell inhibitory receptor (KIR2DL3) specific for HLA-Cw3-related MHC class I.
Structure Fold.Des., 7, 1999
2L7U
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Structure of CEL-PEP-RAGE V domain complex
分子名称: Advanced glycosylation end product-specific receptor, Serum albumin peptide
著者Xue, J, Rai, V, Schmidt, A, Frolov, S, Reverdatto, S, Singer, D, Chabierski, S, Xie, J, Burz, D, Shekhtman, A, Hoffman, R.
登録日2010-12-23
公開日2011-05-18
最終更新日2023-11-29
実験手法SOLUTION NMR
主引用文献Advanced glycation end product recognition by the receptor for AGEs.
Structure, 19, 2011
8TUI
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Crystal structure of Fab-Lirilumab bound to KIR2DL3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Killer cell immunoglobulin-like receptor 2DL3, Lirilumab Fab Heavy Chain, ...
著者Lorig-Roach, N, DuBois, R.M.
登録日2023-08-16
公開日2023-12-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for the activity and specificity of the immune checkpoint inhibitor lirilumab.
Sci Rep, 14, 2024
1UCT
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Crystal structure of the extracellular fragment of Fc alpha Receptor I (CD89)
分子名称: Immunoglobulin alpha Fc receptor
著者Ding, Y, Xu, G, Yang, M, Zhang, W, Rao, Z.
登録日2003-04-21
公開日2003-07-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Ectodomain of Human Fc{alpha}RI.
J.Biol.Chem., 278, 2003
1M4K
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Crystal structure of the human natural killer cell activator receptor KIR2DS2 (CD158j)
分子名称: 1,2-ETHANEDIOL, KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR 2DS2, SULFATE ION
著者Saulquin, X, Gastinel, L.N, Vivier, E.
登録日2002-07-03
公開日2003-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the human natural killer cell activating receptor KIR2DS2 (CD158j)
J.EXP.MED., 197, 2003
4ETY
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Crystal structure of a strand-swapped dimer of Mouse Leukocyte-associated immunoglobulin-like receptor 1 (NYSGRC-006047) Extra Cellular Domain
分子名称: 1,2-ETHANEDIOL, Leukocyte-associated immunoglobulin-like receptor 1
著者Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
登録日2012-04-24
公開日2012-06-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a strand-swapped dimer of Mouse Leukocyte-associated immunoglobulin-like receptor 1 Extra Cellular Domain
to be published
4ESK
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Crystal structure of a strand-swapped dimer of Mouse Leukocyte-associated immunoglobulin-like receptor 1 (NYSGRC-006047)IG-like domain
分子名称: GLYCEROL, Leukocyte-associated immunoglobulin-like receptor 1, POTASSIUM ION, ...
著者Sampathkumar, P, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
登録日2012-04-23
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.762 Å)
主引用文献Crystal structure of a strand-swapped dimer of Mouse Leukocyte-associated immunoglobulin-like receptor 1 IG-like domain
to be published
8F60
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anti-BTLA monoclonal antibody r23C8 in complex with BTLA
分子名称: ACETATE ION, B- and T-lymphocyte attenuator, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hendle, J, Atwell, S, Lieu, R, Hickey, M, Weichert, K.
登録日2022-11-15
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA.
Structure, 31, 2023
8F6O
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anti-BTLA monoclonal antibody h22B3 in complex with BTLA
分子名称: B- and T-lymphocyte attenuator, h22B3 Fab heavy chain, h22B3 Fab light chain
著者Hendle, J, Atwell, S, Lieu, R, Hickey, M, Weichert, K.
登録日2022-11-16
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA.
Structure, 31, 2023
8F6L
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anti-BTLA monoclonal antibody h25F7 in complex with BTLA
分子名称: B- and T-lymphocyte attenuator, h25F7 Fab heavy chain, h25F7 Fab light chain
著者Hendle, J, Atwell, S, Lieu, R, Hickey, M, Weichert, K.
登録日2022-11-16
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA.
Structure, 31, 2023
6IAP
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structure of human NKp46 in complex with antibody NKp46-1 and NKp46-4
分子名称: Fab NKp46-1 heavy chain, Fab NKp46-1 light chain, Fab NKp46-4 heavy chain, ...
著者Roussel, A, Amigues, B.
登録日2018-11-27
公開日2019-06-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Multifunctional Natural Killer Cell Engagers Targeting NKp46 Trigger Protective Tumor Immunity.
Cell, 177, 2019
3H8N
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Crystal Structure Analysis of KIR2DS4
分子名称: Killer cell immunoglobulin-like receptor 2DS4
著者Graef, T, Bushnell, D.A, Parham, P.
登録日2009-04-29
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.
J.Exp.Med., 206, 2009
6NYP
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Crystal structure of UL144/BTLA complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, B- and T-lymphocyte attenuator, GLYCEROL, ...
著者Aruna, B, Zajonc, D.M, Doukov, T.
登録日2019-02-11
公開日2019-05-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of human cytomegalovirus UL144, an HVEM orthologue, bound to the B and T cell lymphocyte attenuator.
J.Biol.Chem., 294, 2019
1NKR
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INHIBITORY RECEPTOR (P58-CL42) FOR HUMAN NATURAL KILLER CELLS
分子名称: P58-CL42 KIR
著者Fan, Q.R, Mosyak, L, Winter, C.C, Wagtmann, N, Long, E.O, Wiley, D.C.
登録日1998-06-24
公開日1998-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors.
Nature, 389, 1997
1OVZ
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Crystal structure of human FcaRI
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Herr, A.B, Ballister, E.R, Bjorkman, P.J.
登録日2003-03-27
公開日2003-05-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Insights into IgA-mediated immune responses from the crystal structures of human Fc-alpha-RI and its complex with IgA1-Fc
Nature, 423, 2003
1P6F
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Structure of the human natural cytotoxicity receptor NKp46
分子名称: natural cytotoxicity triggering receptor 1
著者Foster, C.E, Colonna, M, Sun, P.D.
登録日2003-04-29
公開日2003-12-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the human natural killer (NK) cell activating receptor NKp46 reveals structural relationship to other leukocyte receptor complex immunoreceptors.
J.Biol.Chem., 278, 2003
1OLL
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Extracellular region of the human receptor NKp46
分子名称: 1,2-ETHANEDIOL, NK RECEPTOR
著者Ponassi, M, Cantoni, C, Biassoni, R, Conte, R, Spallarossa, A, Pesce, A, Moretta, A, Moretta, L, Bolognesi, M, Bordo, D.
登録日2003-08-07
公開日2003-09-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of the Human Nk Cell Triggering Receptor Nkp46 Ectodomain
Biochem.Biophys.Res.Commun., 309, 2003
3S36
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Structural basis for the function of two anti-VEGF receptor antibodies
分子名称: 1121B heavy chain, 1121B light chain, Vascular endothelial growth factor receptor 2
著者Franklin, M.C.
登録日2011-05-17
公開日2011-08-24
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
3S35
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Structural basis for the function of two anti-VEGF receptor antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6.64 Fab heavy chain, ...
著者Franklin, M.C.
登録日2011-05-17
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
3S37
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Structural basis for the function of two anti-VEGF receptor antibodies
分子名称: 1121B Fab heavy chain, 1121B Fab light chain, Vascular endothelial growth factor receptor 2
著者Franklin, M.C.
登録日2011-05-17
公開日2011-08-24
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structural Basis for the Function of Two Anti-VEGF Receptor 2 Antibodies.
Structure, 19, 2011
8DGG
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Structure of glycosylated LAG-3 homodimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Silberstein, J.L, Mathews, I.I, Frank, J.A, Chan, K.-W, Fernandez, D, Du, J, Wang, J, Kong, X.-P, Cochran, J.R.
登録日2022-06-23
公開日2022-08-17
最終更新日2022-08-31
実験手法X-RAY DIFFRACTION (3.78 Å)
主引用文献Structural basis for LAG-3 dimeric association and inhibition of T cell function
To Be Published
2CKN
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NMR Structure of the First Ig Module of mouse FGFR1
分子名称: BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1
著者Kiselyov, V.V, Bock, E, Berezin, V, Poulsen, F.M.
登録日2006-04-20
公開日2006-05-31
最終更新日2020-01-15
実験手法SOLUTION NMR
主引用文献NMR Structure of the First Ig Module of Mouse Fgfr1.
Protein Sci., 15, 2006
2CR3
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Solution structure of the first Ig-like domain of human fibroblast growth factor receptor 1
分子名称: Basic fibroblast growth factor receptor 1
著者Hatta, R, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-20
公開日2005-11-20
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of the first Ig-like domain of human fibroblast growth factor receptor 1
To be Published
2DLI
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KILLER IMMUNOGLOBULIN RECEPTOR 2DL2,TRIGONAL FORM
分子名称: PROTEIN (MHC CLASS I NK CELL RECEPTOR PRECURSOR)
著者Sun, P.D, Snyder, G.A.
登録日1999-03-08
公開日2000-01-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2
Proc.Natl.Acad.Sci.USA, 96, 1999
2DL2
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KILLER IMMUNOGLOBULIN RECEPTOR 2DL2
分子名称: PROTEIN (MHC CLASS I NK CELL RECEPTOR PRECURSOR (P58 NATURAL KILLER CELL RECEPTOR CLONE CL-43))
著者Sun, P, Snyder, G.
登録日1999-03-08
公開日1999-03-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2
Proc.Natl.Acad.Sci.USA, 96, 1999

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