3H8N
Crystal Structure Analysis of KIR2DS4
Summary for 3H8N
Entry DOI | 10.2210/pdb3h8n/pdb |
Related | 1efx 1im9 |
Descriptor | Killer cell immunoglobulin-like receptor 2DS4 (2 entities in total) |
Functional Keywords | ligand-binding domains, cell membrane, disulfide bond, glycoprotein, immunoglobulin domain, membrane, polymorphism, receptor, transmembrane, immune system |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein: P43632 |
Total number of polymer chains | 1 |
Total formula weight | 21534.24 |
Authors | Graef, T.,Bushnell, D.A.,Parham, P. (deposition date: 2009-04-29, release date: 2009-10-20, Last modification date: 2023-09-06) |
Primary citation | Graef, T.,Moesta, A.K.,Norman, P.J.,Abi-Rached, L.,Vago, L.,Older Aguilar, A.M.,Gleimer, M.,Hammond, J.A.,Guethlein, L.A.,Bushnell, D.A.,Robinson, P.J.,Parham, P. KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C. J.Exp.Med., 206:2557-2572, 2009 Cited by PubMed: 19858347DOI: 10.1084/jem.20091010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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