1EFX

STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3

Summary for 1EFX

• Entry DOI: 10.2210/pdb1efx/pdb
• Related: 2dl2
• Descriptor: HLA-CW3 (HEAVY CHAIN), BETA-2-MICROGLOBULIN, PEPTIDE FROM IMPORTIN ALPHA-2, ... (5 entities in total)
• Functional Keywords: mhc, hla, class i, kir, nk cell receptor, immunoglobulin fold, receptor-mhc complex, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P61769; Cytoplasm: P52292; Cell membrane; Single-pass type I membrane protein: P43627
• Total number of polymer chains: 5
• Total formula weight: 89034.14

Authors

Boyington, J.C.,Motyka, S.A.,Schuck, P.,Brooks, A.G.,Sun, P.D. (deposition date: 2000-02-10, release date: 2000-06-14, Last modification date: 2023-08-09)

• Primary citation: Boyington, J.C.,Motyka, S.A.,Schuck, P.,Brooks, A.G.,Sun, P.D.; Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand.; Nature, 405:537-543, 2000; PubMed: 10850706; DOI: 10.1038/35014520

Experimental method

X-RAY DIFFRACTION (3 Å)