2VFX
 
 | | Structure of the Symmetric Mad2 Dimer | | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ... | | Authors: | Yang, M, Li, B, Liu, C.-J, Tomchick, D.R, Machius, M, Rizo, J, Yu, H, Luo, X. | | Deposit date: | 2007-11-05 | | Release date: | 2008-03-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer.
Plos Biol., 6, 2008
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2GJ5
 | | Crystal structure of a secondary vitamin D3 binding site of milk beta-lactoglobulin | | Descriptor: | (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLI DENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL, Beta-lactoglobulin | | Authors: | Yang, M.C, Guan, H.H, Liu, M.Y, Yang, J.M, Chen, W.L, Chen, C.J, Mao, S.J. | | Deposit date: | 2006-03-30 | | Release date: | 2007-10-02 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of a secondary vitamin D3 binding site of milk beta-lactoglobulin.
Proteins, 71, 2008
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6PIK
 | | Tetrameric cryo-EM ArnA | | Descriptor: | Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase | | Authors: | Yang, M, Gehring, K. | | Deposit date: | 2019-06-26 | | Release date: | 2019-07-31 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
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6PIH
 | | Hexameric ArnA cryo-EM structure | | Descriptor: | Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase | | Authors: | Yang, M, Gehring, K. | | Deposit date: | 2019-06-26 | | Release date: | 2019-07-31 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
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2LQJ
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2UXN
 | | Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation | | Descriptor: | CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | Authors: | Yang, M, Culhane, J.C, Szewczuk, L.M, Gocke, C.B, Brautigam, C.A, Tomchick, D.R, Machius, M, Cole, P.A, Yu, H. | | Deposit date: | 2007-03-28 | | Release date: | 2007-05-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.72 Å) | | Cite: | Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation.
Nat.Struct.Mol.Biol., 14, 2007
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2UXX
 | | Human LSD1 Histone Demethylase-CoREST in complex with an FAD- tranylcypromine adduct | | Descriptor: | CHLORIDE ION, FAD-trans-2-Phenylcyclopropylamine Adduct, GLYCEROL, ... | | Authors: | Yang, M, Culhane, J.C, Machius, M, Cole, P.A, Yu, H. | | Deposit date: | 2007-03-30 | | Release date: | 2007-08-21 | | Last modified: | 2019-02-06 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | Structural Basis for the Inhibition of the Lsd1 Histone Demethylase by the Antidepressant Trans-2-Phenylcyclopropylamine.
Biochemistry, 46, 2007
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4IKG
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2IW5
 | | Structural Basis for CoREST-Dependent Demethylation of Nucleosomes by the Human LSD1 Histone Demethylase | | Descriptor: | AMMONIUM ION, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Yang, M, Gocke, C.B, Luo, X, Borek, D, Tomchick, D.R, Machius, M, Otwinowski, Z, Yu, H. | | Deposit date: | 2006-06-26 | | Release date: | 2006-08-09 | | Last modified: | 2019-02-06 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | Structural Basis for Corest-Dependent Demethylation of Nucleosomes by the Human Lsd1 Histone Demethylase
Mol.Cell, 23, 2006
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4PSX
 | | Crystal structure of histone acetyltransferase complex | | Descriptor: | COENZYME A, Histone H3, Histone H4, ... | | Authors: | Yang, M, Li, Y. | | Deposit date: | 2014-03-08 | | Release date: | 2014-07-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.509 Å) | | Cite: | Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
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4F24
 | | Crystal structures reveal the multi-ligand binding mechanism of the Staphylococcus aureus ClfB | | Descriptor: | Clumping factor B, MAGNESIUM ION | | Authors: | Yang, M.J, Xiang, H, Wang, J.W, Liu, B, Chen, Y.G, Liu, L, Deng, X.M, Feng, Y. | | Deposit date: | 2012-05-07 | | Release date: | 2012-08-08 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.509 Å) | | Cite: | Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
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4F1Z
 | | Crystal structures reveal the multi-ligand binding mechanism of the Staphylococcus aureus ClfB | | Descriptor: | Clumping factor B, MAGNESIUM ION, peptide from Keratin, ... | | Authors: | Yang, M.J, Xiang, H, Wang, J.W, Liu, B, Chen, Y.G, Liu, L, Deng, X.M, Feng, Y. | | Deposit date: | 2012-05-07 | | Release date: | 2012-08-08 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
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4F27
 | | Crystal structures reveal the multi-ligand binding mechanism of the Staphylococcus aureus ClfB | | Descriptor: | Clumping factor B, MAGNESIUM ION, peptide from Fibrinogen alpha chain | | Authors: | Yang, M.J, Xiang, H, Wang, J.W, Liu, B, Chen, Y.G, Liu, L, Deng, X.M, Feng, Y. | | Deposit date: | 2012-05-07 | | Release date: | 2012-08-08 | | Last modified: | 2015-02-04 | | Method: | X-RAY DIFFRACTION (1.917 Å) | | Cite: | Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
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4F20
 | | Crystal structures reveal the multi-ligand binding mechanism of the Staphylococcus aureus ClfB | | Descriptor: | Clumping factor B, MAGNESIUM ION, peptide from Dermokine | | Authors: | Yang, M.J, Xiang, H, Wang, J.W, Liu, B, Chen, Y.G, Liu, L, Deng, X.M, Feng, Y. | | Deposit date: | 2012-05-07 | | Release date: | 2012-08-08 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Crystal Structures Reveal the Multi-Ligand Binding Mechanism of Staphylococcus aureus ClfB
Plos Pathog., 8, 2012
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5WY5
 | | Crystal structure of MAGEG1 and NSE1 complex | | Descriptor: | MAGNESIUM ION, Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ... | | Authors: | Yang, M, Gao, J. | | Deposit date: | 2017-01-11 | | Release date: | 2017-05-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010
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4PSW
 | | Crystal structure of histone acetyltransferase complex | | Descriptor: | COENZYME A, Histone H4 type VIII, Histone acetyltransferase type B catalytic subunit, ... | | Authors: | Yang, M, Li, Y. | | Deposit date: | 2014-03-08 | | Release date: | 2014-07-09 | | Method: | X-RAY DIFFRACTION (2.101 Å) | | Cite: | Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
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4NQJ
 | | Structure of coiled-coil domain | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, E3 ubiquitin-protein ligase TRIM69 | | Authors: | Yang, M, Li, Y. | | Deposit date: | 2013-11-25 | | Release date: | 2014-05-21 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.152 Å) | | Cite: | Structural insights into the TRIM family of ubiquitin E3 ligases.
Cell Res., 24, 2014
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2H2N
 | | Crystal structure of human soluble calcium-activated nucleotidase (SCAN) with calcium ion | | Descriptor: | ACETATE ION, CALCIUM ION, Soluble calcium-activated nucleotidase 1 | | Authors: | Yang, M, Horii, K, Herr, A.B, Kirley, T.L. | | Deposit date: | 2006-05-19 | | Release date: | 2006-07-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
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2H2U
 | | Crystal structure of the E130Y mutant of human soluble calcium-activated nucleotidase (SCAN) with calcium ion | | Descriptor: | CALCIUM ION, Soluble calcium-activated nucleotidase 1 | | Authors: | Yang, M, Horii, K, Herr, A.B, Kirley, T.L. | | Deposit date: | 2006-05-19 | | Release date: | 2006-07-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
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3T9N
 | | Crystal structure of a membrane protein | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Small-conductance mechanosensitive channel | | Authors: | Yang, M, Zhang, X, Ge, J, Wang, J. | | Deposit date: | 2011-08-03 | | Release date: | 2012-10-31 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.456 Å) | | Cite: | Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance
Proc.Natl.Acad.Sci.USA, 109, 2012
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4HY6
 | | Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1 | | Descriptor: | 6,6-dimethyl-3-(trifluoromethyl)-1,5,6,7-tetrahydro-4H-indazol-4-one, Heat shock protein HSP 90-alpha | | Authors: | Yang, M, Li, J, He, J.H. | | Deposit date: | 2012-11-13 | | Release date: | 2013-05-15 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.649 Å) | | Cite: | Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1
to be published
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7CK6
 | | Protein translocase of mitochondria | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, ... | | Authors: | Yang, M, Wang, W, Zhang, L, Chen, X. | | Deposit date: | 2020-07-15 | | Release date: | 2020-11-04 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Atomic structure of human TOM core complex.
Cell Discov, 6, 2020
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5YE2
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5YE1
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5YE5
 | | structure of endo-lysosomal TRPML1 channel inserting into nanodisc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, mammalian endo-lysosomal TRPML1 channel | | Authors: | Yang, M, Gao, N. | | Deposit date: | 2017-09-15 | | Release date: | 2017-11-15 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (5.8 Å) | | Cite: | Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
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