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3TFM	Myosin X PH1N-PH2-PH1C tandem Descriptor: Myosin X, PHOSPHATE ION Authors: Yu, J, Lu, Q, Yan, J, Wei, Z, Zhang, M. Deposit date: 2011-08-16 Release date: 2011-12-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor MOLECULAR BIOLOGY OF THE CELL, 22, 2011
2F6H	Myosin V cargo binding domain Descriptor: Myosin-2 Authors: Pashkova, N, Jin, Y, Ramaswamy, S, Weisman, L.S. Deposit date: 2005-11-29 Release date: 2006-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural basis for myosin V discrimination between distinct cargoes Embo J., 25, 2006
3GN4	Myosin lever arm Descriptor: CALCIUM ION, Calmodulin, MAGNESIUM ION, ... Authors: Mukherjea, M, Llinas, P, Kim, H, Travaglia, M, Safer, D, Zong, A.B, Menetrey, J, Franzini-Armstrong, C, Selvin, P.R, Houdusse, A, Sweeney, H.L. Deposit date: 2009-03-16 Release date: 2009-09-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach Mol.Cell, 35, 2009
2XMF	Myosin 1e SH3 Descriptor: MYOSIN 1E SH3, OCTANE 1,8-DIAMINE Authors: Edwards, T, Allsop, G, Peckham, M. Deposit date: 2010-07-27 Release date: 2011-08-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Myosin 1E SH3 To be Published
2KIA	Solution structure of Myosin VI C-terminal cargo-binding domain Descriptor: Myosin-VI Authors: Feng, W, Yu, C, Wei, Z, Miyanoiri, Y, Zhang, M. Deposit date: 2009-04-29 Release date: 2009-09-29 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Myosin VI undergoes cargo-mediated dimerization Cell(Cambridge,Mass.), 138, 2009
2TMA	TROPOMYOSIN CRYSTAL STRUCTURE AND MUSCLE REGULATION. APPENDIX. CONSTRUCTION OF AN ATOMIC MODEL FOR TROPOMYOSIN AND IMPLICATIONS FOR INTERACTIONS WITH ACTIN Descriptor: TROPOMYOSIN Authors: Phillips Jr, G.N, Cohen, C. Deposit date: 1987-09-16 Release date: 1987-10-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (15 Å) Cite: Construction of an atomic model for tropomyosin and implications for interactions with actin. J.Mol.Biol., 192, 1986
4ANJ	MYOSIN VI (MDinsert2-GFP fusion) PRE-POWERSTROKE STATE (MG.ADP.AlF4) Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, CALMODULIN, ... Authors: Menetrey, J, Isabet, T, Ropars, V, Mukherjea, M, Pylypenko, O, Liu, X, Perez, J, Vachette, P, Sweeney, H.L, Houdusse, A.M. Deposit date: 2012-03-19 Release date: 2012-10-17 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin Vi. Mol.Cell, 48, 2012
5EJS	Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain, mutant 1 Descriptor: Myosin-I heavy chain Authors: Planelles-Herrero, V.J, Sirkia, H, Sourigues, Y, Titus, M.A, Houdusse, A. Deposit date: 2015-11-02 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Myosin MyTH4-FERM structures highlight important principles of convergent evolution. Proc.Natl.Acad.Sci.USA, 113, 2016
5HMP	Myosin Vc pre-powerstroke state Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ... Authors: Ropars, V, Pylypenko, O, Sweeney, H.L, Houdusse, A. Deposit date: 2016-01-16 Release date: 2016-09-07 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.397 Å) Cite: The myosin X motor is optimized for movement on actin bundles. Nat Commun, 7, 2016
4E7S	Myosin VI D23R I24R R569E (MD) pre-powerstroke state Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... Authors: Isabet, T, Sweeney, H.L, Houdusse, A. Deposit date: 2012-03-19 Release date: 2012-09-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI. Mol.Cell, 48, 2012
5HMO	myosin X motor activity Descriptor: Unconventional myosin-X Authors: Ropars, V, Blanc, F, Samazan, F, Houdusse, A. Deposit date: 2016-01-16 Release date: 2016-09-07 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.493 Å) Cite: The myosin X motor is optimized for movement on actin bundles. Nat Commun, 7, 2016
5O2L	Myosin VI motor domain in the Pre-Transition State Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, GLYCEROL, ... Authors: Isabet, T, Benisty, H, Houdusse, A. Deposit date: 2017-05-22 Release date: 2018-05-23 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.2 Å) Cite: An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4E7Z	Myosin VI (MD) pre-powerstroke state, P21 crystal form Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... Authors: Isabet, T, Sweeney, H.L, Houdusse, A. Deposit date: 2012-03-19 Release date: 2012-09-19 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI. Mol.Cell, 48, 2012
8ARD	Myosin VI proximal tail domain, dimeric Descriptor: Unconventional myosin-VI Authors: Kikuti, C.M, Sirkia, H, Houdusse, A. Deposit date: 2022-08-16 Release date: 2023-08-30 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (2.219 Å) Cite: How myosin VI traps its off-state, is activated and dimerizes. Nat Commun, 14, 2023
2AVG	NMR structure of cC1 domain from Human Cardiac Myosin Binding Protein C Descriptor: Myosin-binding protein C, cardiac-type Authors: Ababou, A, Gautel, M, Pfuhl, M. Deposit date: 2005-08-30 Release date: 2006-09-05 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Myosin binding protein C positioned to play a key role in regulation of muscle contraction: structure and interactions of domain C1. J.Mol.Biol., 384, 2008
2VAS	Myosin VI (MD-insert2-CaM, Delta-Insert1) Post-rigor state Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ... Authors: Menetrey, J, Llinas, P, Cicolari, J, Squires, G, Liu, X, Li, A, Sweeney, H.L, Houdusse, A. Deposit date: 2007-09-04 Release date: 2007-12-11 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The Post-Rigor Structure of Myosin Vi and Implications for the Recovery Stroke. Embo J., 27, 2008
2VB6	Myosin VI (MD-insert2-CaM, Delta Insert1) Post-rigor state (crystal form 2) Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ... Authors: Menetrey, J, Llinas, P, Cicolari, J, Squires, G, Liu, X, Li, A, Sweeney, H.L, Houdusse, A. Deposit date: 2007-09-06 Release date: 2007-12-11 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The Post-Rigor Structure of Myosin Vi and Implications for the Recovery Stroke. Embo J., 27, 2008
6KLQ	Tropomyosin of cardiac thin filament in high-calcium state Descriptor: Tropomyosin Authors: Oda, T, Yanagisawa, H, Wakabayashi, T. Deposit date: 2019-07-30 Release date: 2020-01-15 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (7.7 Å) Cite: Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin. J.Struct.Biol., 209, 2020
6KLP	Tropomyosin of cardiac thin filament in low-calcium state Descriptor: Tropomyosin Authors: Oda, T, Yanagisawa, H, Wakabayashi, T. Deposit date: 2019-07-30 Release date: 2020-01-15 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (6.6 Å) Cite: Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin. J.Struct.Biol., 209, 2020
1C1G	CRYSTAL STRUCTURE OF TROPOMYOSIN AT 7 ANGSTROMS RESOLUTION IN THE SPERMINE-INDUCED CRYSTAL FORM Descriptor: TROPOMYOSIN Authors: Whitby, F.G, Phillips Jr, G.N. Deposit date: 1999-07-22 Release date: 2000-02-11 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (7 Å) Cite: Crystal structure of tropomyosin at 7 Angstroms resolution. Proteins, 38, 2000
6Z7U	Myosin-II motor domain complexed with blebbistatin in a new ADP-release conformation Descriptor: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... Authors: Ewert, W, Preller, M. Deposit date: 2020-06-01 Release date: 2020-10-21 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Structural and Computational Insights into a Blebbistatin-Bound Myosin•ADP Complex with Characteristics of an ADP-Release Conformation along the Two-Step Myosin Power Stoke. Int J Mol Sci, 21, 2020
4ZG4	Myosin Vc Pre-powerstroke Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Ropars, V, Pylypenko, O, Sweeney, L, Houdusse, A. Deposit date: 2015-04-22 Release date: 2016-03-23 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Force-producing ADP state of myosin bound to actin. Proc.Natl.Acad.Sci.USA, 113, 2016
7B1A	Myosin-II-AA mutant motor domain Descriptor: 1,2-ETHANEDIOL, ADP METAVANADATE, MAGNESIUM ION, ... Authors: Ewert, W, Preller, M. Deposit date: 2020-11-24 Release date: 2021-01-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Unraveling a Force-Generating Allosteric Pathway of Actomyosin Communication Associated with ADP and P i Release. Int J Mol Sci, 22, 2020
4PJJ	MYOSIN VI (MD-INSERT2-CAM, DELTA-INSERT1) post-rigor state - long soaking with PO4 Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calmodulin, ... Authors: Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. Deposit date: 2014-05-12 Release date: 2015-04-29 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015
4PJL	Myosin VI motor domain A458E mutant in the Pi release state, space group P212121 - Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... Authors: Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. Deposit date: 2014-05-12 Release date: 2015-04-29 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015

 

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