5TDE
 
 | | TEV Cleaved Human ATP Citrate Lyase Bound to Citrate | | Descriptor: | ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ... | | Authors: | Hu, J, Fraser, M.E. | | Deposit date: | 2016-09-19 | | Release date: | 2017-08-09 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
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8RJL
 | | Structure of a first order Sierpinski triangle formed by the H369R mutant of the citrate synthase from Synechococcus elongatus | | Descriptor: | Citrate synthase | | Authors: | Lo, Y.K, Bohn, S, Sendker, F.L, Schuller, J.M, Hochberg, G. | | Deposit date: | 2023-12-21 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.34 Å) | | Cite: | Emergence of fractal geometries in the evolution of a metabolic enzyme.
Nature, 628, 2024
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8RJK
 | | Pseudoatomic model of a second-order Sierpinski triangle formed by the citrate synthase from Synechococcus elongatus | | Descriptor: | Citrate synthase | | Authors: | Lo, Y.K, Bohn, S, Sendker, F.L, Schuller, J.M, Hochberg, G. | | Deposit date: | 2023-12-21 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (5.91 Å) | | Cite: | Emergence of fractal geometries in the evolution of a metabolic enzyme.
Nature, 628, 2024
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8GMF
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1AMZ
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1AL6
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8BP7
 | | Citrate-bound hexamer of Synechococcus elongatus citrate synthase | | Descriptor: | CITRIC ACID, Citrate synthase, MAGNESIUM ION, ... | | Authors: | Mais, C.-N, Sendker, F, Bange, G. | | Deposit date: | 2022-11-16 | | Release date: | 2024-04-24 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Emergence of fractal geometries in the evolution of a metabolic enzyme.
Nature, 628, 2024
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8S97
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8GM9
 | | Structure of Citrate Synthase(CitA) in Mycobacterium Tuberculosis | | Descriptor: | 1,2-ETHANEDIOL, ACRYLIC ACID, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Pathirage, R, Ronning, D, Favrot, L. | | Deposit date: | 2023-03-24 | | Release date: | 2023-06-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
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8GLL
 | | R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | | Authors: | Pathirage, R, Ronning, D, Petit, C. | | Deposit date: | 2023-03-22 | | Release date: | 2023-06-07 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
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8GLB
 | | Selenomethionine Derivatized Citrate Synthase (CitA) in Mycobacterium tuberculosis with Pyruvate | | Descriptor: | 1,2-ETHANEDIOL, PYRUVIC ACID, citrate synthase | | Authors: | Pathirage, R, Ronning, D, Favrot, L. | | Deposit date: | 2023-03-21 | | Release date: | 2023-06-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
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8GMK
 | | Pyruvate bound structure of Citrate Synthase (CitA) in Mycobacterium Tuberculosis | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PYRUVIC ACID, ... | | Authors: | Pathirage, R, Ronning, D, Yamsek, M. | | Deposit date: | 2023-03-26 | | Release date: | 2023-06-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
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8GQZ
 | | Crystal structure of mitochondrial citrate synthase (Cit1) from Saccharomyces cerevisiae | | Descriptor: | ACETATE ION, CHLORIDE ION, Citrate synthase, ... | | Authors: | Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. | | Deposit date: | 2022-08-31 | | Release date: | 2023-04-26 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
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8GR8
 | | Crystal structure of peroxisomal citrate synthase (Cit2) from Saccharomycescerevisiae | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Citrate synthase, ... | | Authors: | Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. | | Deposit date: | 2022-09-01 | | Release date: | 2023-04-26 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
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8GR9
 | | Crystal structure of peroxisomal citrate synthase (Cit2) from Saccharomyces cerevisiae in complex with oxaloacetate and coenzyme-A | | Descriptor: | CHLORIDE ION, COENZYME A, Citrate synthase, ... | | Authors: | Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. | | Deposit date: | 2022-09-01 | | Release date: | 2023-04-26 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress.
Sci Adv, 9, 2023
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4TVO
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2IBP
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5LQM
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6HXP
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6XOW
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3O8J
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6POE
 | | Structure of ACLY in complex with CoA | | Descriptor: | ATP-citrate synthase, COENZYME A | | Authors: | Wei, X, Marmorstein, R. | | Deposit date: | 2019-07-03 | | Release date: | 2019-12-25 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
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5F35
 | | Structure of quinolinate synthase in complex with citrate | | Descriptor: | CITRATE ANION, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | Authors: | Volbeda, A, Fontecilla-Camps, J.C. | | Deposit date: | 2015-12-02 | | Release date: | 2016-08-31 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal Structures of Quinolinate Synthase in Complex with a Substrate Analogue, the Condensation Intermediate, and Substrate-Derived Product.
J.Am.Chem.Soc., 138, 2016
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6UV5
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5TDZ
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